FR2523131B1 - N- (8A-ERGOLINYL) -N ', N'-DIETHYLUREES SUBSTITUTED IN 1 AND PROCESS FOR OBTAINING THESE COMPOUNDS - Google Patents

N- (8A-ERGOLINYL) -N ', N'-DIETHYLUREES SUBSTITUTED IN 1 AND PROCESS FOR OBTAINING THESE COMPOUNDS

Info

Publication number
FR2523131B1
FR2523131B1 FR8304005A FR8304005A FR2523131B1 FR 2523131 B1 FR2523131 B1 FR 2523131B1 FR 8304005 A FR8304005 A FR 8304005A FR 8304005 A FR8304005 A FR 8304005A FR 2523131 B1 FR2523131 B1 FR 2523131B1
Authority
FR
France
Prior art keywords
diethylurees
ergolinyl
substituted
compounds
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8304005A
Other languages
French (fr)
Other versions
FR2523131A1 (en
Inventor
Antonin Cerny
Jiri Krepelka
Karel Rezabek
Miroslav Seda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Vereinigte Pharma Werke
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of FR2523131A1 publication Critical patent/FR2523131A1/en
Application granted granted Critical
Publication of FR2523131B1 publication Critical patent/FR2523131B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8304005A 1982-03-12 1983-03-11 N- (8A-ERGOLINYL) -N ', N'-DIETHYLUREES SUBSTITUTED IN 1 AND PROCESS FOR OBTAINING THESE COMPOUNDS Expired FR2523131B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea

Publications (2)

Publication Number Publication Date
FR2523131A1 FR2523131A1 (en) 1983-09-16
FR2523131B1 true FR2523131B1 (en) 1987-08-28

Family

ID=5352449

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8304005A Expired FR2523131B1 (en) 1982-03-12 1983-03-11 N- (8A-ERGOLINYL) -N ', N'-DIETHYLUREES SUBSTITUTED IN 1 AND PROCESS FOR OBTAINING THESE COMPOUNDS

Country Status (15)

Country Link
JP (1) JPS58180484A (en)
AT (1) AT383349B (en)
AU (1) AU555961B2 (en)
BE (1) BE896122A (en)
CA (1) CA1203531A (en)
CH (1) CH652125A5 (en)
CS (1) CS231214B1 (en)
DE (1) DE3308719A1 (en)
DK (1) DK84683A (en)
FI (1) FI830754L (en)
FR (1) FR2523131B1 (en)
GB (1) GB2116548B (en)
IT (1) IT1161209B (en)
NL (1) NL8300829A (en)
SE (1) SE452321B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (en) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen NEW ERGOLIN DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE AS A MEDICINAL PRODUCT
EP0208417A3 (en) * 1985-06-12 1989-09-06 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis
DE3522894A1 (en) * 1985-06-24 1987-01-02 Schering Ag USE OF TERGURID AS GERIATRIC
FR2584720B1 (en) * 1985-07-11 1987-10-02 Rhone Poulenc Sante PROCESS FOR THE PREPARATION OF N-METHYL DERIVATIVES OF ERGOLINE
DE3620293A1 (en) * 1986-06-16 1987-12-17 Schering Ag 1 AND / OR 2 SUBSTITUTED ERGOL DERIVATIVES
DE3623503A1 (en) * 1986-07-09 1988-01-21 Schering Ag 1-ARYL-ERGOLINYL-UREA DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE USE OF THESE COMPOUNDS AS A MEDICINAL PRODUCT
DE10212564B4 (en) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl ergot alkaloid derivatives and their use for the prophylaxis and treatment of migraine
JP2014501710A (en) * 2010-11-11 2014-01-23 ジノクサ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング Use of lisuride, terguride, and their derivatives for the prevention and / or treatment of fibrous degeneration
US9676776B2 (en) 2015-01-20 2017-06-13 Xoc Pharmaceuticals, Inc. Isoergoline compounds and uses thereof
EP3253753A4 (en) 2015-01-20 2018-06-27 Xoc Pharmaceuticals, Inc Ergoline compounds and uses thereof
AU2018275873A1 (en) 2017-06-01 2019-12-19 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH344731A (en) * 1956-05-18 1960-02-29 Sandoz Ag Process for the production of new derivatives of the lysergic acid series alkylated on the indole nitrogen
AT231082B (en) * 1960-10-12 1964-01-10 Sandoz Ag Process for the production of new urea derivatives
EP0021206B1 (en) * 1979-06-13 1983-06-22 Schering Aktiengesellschaft (ergolin-yl)-n', n'-diethyl urea derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
SE8301257D0 (en) 1983-03-08
JPS58180484A (en) 1983-10-21
CA1203531A (en) 1986-04-22
GB8305735D0 (en) 1983-04-07
IT1161209B (en) 1987-03-18
DE3308719A1 (en) 1983-09-22
CH652125A5 (en) 1985-10-31
IT8319935A0 (en) 1983-03-07
AU1216783A (en) 1983-09-15
FI830754L (en) 1983-09-13
NL8300829A (en) 1983-10-03
GB2116548A (en) 1983-09-28
AU555961B2 (en) 1986-10-16
FR2523131A1 (en) 1983-09-16
SE452321B (en) 1987-11-23
AT383349B (en) 1987-06-25
DK84683D0 (en) 1983-02-24
CS231214B1 (en) 1984-10-15
SE8301257L (en) 1983-09-13
GB2116548B (en) 1985-03-20
FI830754A0 (en) 1983-03-07
DK84683A (en) 1983-09-13
BE896122A (en) 1983-07-01
ATA72783A (en) 1986-11-15

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Legal Events

Date Code Title Description
ST Notification of lapse