FR2445966A1 - Procede de normalisation d'un constituant marque - Google Patents
Procede de normalisation d'un constituant marqueInfo
- Publication number
- FR2445966A1 FR2445966A1 FR7901965A FR7901965A FR2445966A1 FR 2445966 A1 FR2445966 A1 FR 2445966A1 FR 7901965 A FR7901965 A FR 7901965A FR 7901965 A FR7901965 A FR 7901965A FR 2445966 A1 FR2445966 A1 FR 2445966A1
- Authority
- FR
- France
- Prior art keywords
- ige
- ligand
- labeled
- relates
- standardizing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000470 constituent Substances 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 4
- 239000013566 allergen Substances 0.000 abstract 1
- 230000002009 allergenic effect Effects 0.000 abstract 1
- 238000000159 protein binding assay Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000013558 reference substance Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/804—Radioisotope, e.g. radioimmunoassay
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
L'invention a trait au domaine paramédical. Elle concerne la standardisation d'un constituant marqué tel qu'un anti-IgE destiné à être utilisé dans une épreuve par fixation spécifique. Le procédé implique la normalisation d'un ligand marqué (par exemple IgE marquée par la radioactivité) vis-à-vis d'une substance contenant un ligand de référence (par exemple l'IgE normale << WHO >>), pour déterminer le poids de protéine d'Ige représentée par le ligand marqué, par rapport à la substance de référence. L'invention concerne également une méthode de détermination du pouvoir d'un extrait allergène. Ce pouvoir est exprimé par le poids de ligand inhibé par l'addition d'un allergène soluble.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/872,668 US4211762A (en) | 1978-01-26 | 1978-01-26 | Specific binding assay techniques |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2445966A1 true FR2445966A1 (fr) | 1980-08-01 |
Family
ID=25360070
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7901965A Pending FR2445966A1 (fr) | 1978-01-26 | 1979-01-25 | Procede de normalisation d'un constituant marque |
Country Status (10)
Country | Link |
---|---|
US (1) | US4211762A (fr) |
AU (1) | AU513556B2 (fr) |
CA (1) | CA1114290A (fr) |
DE (1) | DE2900546C3 (fr) |
DK (1) | DK32579A (fr) |
FI (1) | FI790228A (fr) |
FR (1) | FR2445966A1 (fr) |
GB (1) | GB2013337B (fr) |
NO (1) | NO790252L (fr) |
SE (1) | SE7900343L (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0063064A1 (fr) * | 1981-03-24 | 1982-10-20 | Laboratoire Des Stallergenes | Réactif pour le dosage radio-ou enzymo immunologique des IgE |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2953610C1 (de) * | 1979-03-19 | 1985-04-11 | International Diagnostic Technology, Inc., Santa Clara, Calif. | Verfahren zum Bestimmen eines immunologisch aktiven Stoffs |
DE3168691D1 (en) * | 1980-11-07 | 1985-03-14 | Technicon Instr | Immunoassay of proteins |
US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
FR2503578B1 (fr) * | 1981-04-13 | 1987-07-17 | Guinard Separation | Installation de filtration a coursiers passant entre des plateaux de serrage |
AU580248B2 (en) * | 1982-10-13 | 1989-01-12 | Biowhittaker Technologies, Inc. | Fluorometric assay of allergic reactions and reagents therefor |
US4845027B1 (en) * | 1982-10-13 | 1994-05-10 | Biowhittaker Inc | Fluorometric assay of allergic reactions |
US4528267A (en) * | 1982-11-26 | 1985-07-09 | Axionics, Inc. | Fluorometirc enzyme inhibition immunoassay for measuring potency of allergen extracts |
US4849337A (en) * | 1983-01-31 | 1989-07-18 | Minnesota Mining And Manufacturing Company | Assaying allergen specific IgE levels with fluorogenic enzyme labeled antibody |
US4558013A (en) * | 1983-04-08 | 1985-12-10 | Mast Immunosystems, Ltd. | Calibrated reaction measurement system |
JPS59208462A (ja) * | 1983-04-29 | 1984-11-26 | バイオウィッテッカー・インコーポレーテッド | キモパパインの分析法 |
US4649039A (en) * | 1984-07-03 | 1987-03-10 | E. I. Du Pont De Nemours And Company | Radiolabeling of methionine-containing proteins and peptides |
DE3800048A1 (de) * | 1987-05-14 | 1988-11-24 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung eines antikoerpers in menschlichen koerperfluessigkeiten |
US5231344A (en) * | 1990-01-17 | 1993-07-27 | Hitachi Ltd. | Control apparatus for electric generator |
ATE555387T1 (de) | 2005-10-12 | 2012-05-15 | Allergan Inc | Tests der molekularen oder subzellulären nähe unter verwendung von depolarisierung nach resonanzenergietransfer (daret) |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3720760A (en) * | 1968-09-06 | 1973-03-13 | Pharmacia Ab | Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples |
US3941876A (en) * | 1973-04-25 | 1976-03-02 | Gte New Ventures Corporation | In vitro method for determining allergic hypersensitivity |
-
1978
- 1978-01-26 US US05/872,668 patent/US4211762A/en not_active Expired - Lifetime
- 1978-12-14 CA CA317,964A patent/CA1114290A/fr not_active Expired
-
1979
- 1979-01-08 DE DE2900546A patent/DE2900546C3/de not_active Expired
- 1979-01-15 SE SE7900343A patent/SE7900343L/xx not_active Application Discontinuation
- 1979-01-15 GB GB7901472A patent/GB2013337B/en not_active Expired
- 1979-01-24 FI FI790228A patent/FI790228A/fi not_active IP Right Cessation
- 1979-01-25 NO NO790252A patent/NO790252L/no unknown
- 1979-01-25 AU AU43668/79A patent/AU513556B2/en not_active Ceased
- 1979-01-25 DK DK32579A patent/DK32579A/da unknown
- 1979-01-25 FR FR7901965A patent/FR2445966A1/fr active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3720760A (en) * | 1968-09-06 | 1973-03-13 | Pharmacia Ab | Method for determining the presence of reagin-immunoglobulins(reagin-ig)directed against certain allergens,in aqueous samples |
US3720760B1 (fr) * | 1968-09-06 | 1984-02-07 | Pharmacia Ab | |
US3941876A (en) * | 1973-04-25 | 1976-03-02 | Gte New Ventures Corporation | In vitro method for determining allergic hypersensitivity |
Non-Patent Citations (3)
Title |
---|
EXBK/72 * |
EXBK/73 * |
EXBK/78 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0063064A1 (fr) * | 1981-03-24 | 1982-10-20 | Laboratoire Des Stallergenes | Réactif pour le dosage radio-ou enzymo immunologique des IgE |
Also Published As
Publication number | Publication date |
---|---|
DE2900546B2 (de) | 1980-09-11 |
CA1114290A (fr) | 1981-12-15 |
NO790252L (no) | 1979-07-27 |
AU4366879A (en) | 1979-08-02 |
GB2013337B (en) | 1982-11-17 |
SE7900343L (sv) | 1979-07-27 |
US4211762A (en) | 1980-07-08 |
GB2013337A (en) | 1979-08-08 |
DK32579A (da) | 1979-07-27 |
DE2900546C3 (de) | 1981-05-21 |
AU513556B2 (en) | 1980-12-11 |
FI790228A (fi) | 1979-07-27 |
DE2900546A1 (de) | 1979-08-30 |
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