FR2445338A1 - Preparation de glycoproteine isolee d'enveloppes d'onco-rna virus et vaccins qui la contiennent - Google Patents

Preparation de glycoproteine isolee d'enveloppes d'onco-rna virus et vaccins qui la contiennent

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Publication number
FR2445338A1
FR2445338A1 FR7927645A FR7927645A FR2445338A1 FR 2445338 A1 FR2445338 A1 FR 2445338A1 FR 7927645 A FR7927645 A FR 7927645A FR 7927645 A FR7927645 A FR 7927645A FR 2445338 A1 FR2445338 A1 FR 2445338A1
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FR
France
Prior art keywords
onco
preparation
rna virus
same
vaccines containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7927645A
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English (en)
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FR2445338B1 (fr
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Research Corp
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Research Corp
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Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of FR2445338A1 publication Critical patent/FR2445338A1/fr
Application granted granted Critical
Publication of FR2445338B1 publication Critical patent/FR2445338B1/fr
Granted legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13061Methods of inactivation or attenuation
    • C12N2740/13063Methods of inactivation or attenuation by chemical treatment
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/819Viral vaccine for feline species, e.g. cats

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Glycoprotéine non dénaturée appelée (gp90), isolée d'enveloppes d onco-RNA virus. Elle a une masse moléculaire de 90 000 daltons, elle est formée d'unités de la glycoprotéine gp70 et de la protéine p15 (E), elle est susceptible d'immunoprécipitation avec des sérums anti-gp70 et anti-pl5 (E), elle donne la gp70 et la p15 (E) par réduction avec le mercapto-éthanol, et, en solution aqueuse et en présence de détergents non ioniques, elle se trouve sous la forme d'un complexe ayant une masse moléculaire de 360 000 à 450 000. Elle peut être obtenue à partir du virus de la leucémie féline ou de la leucémie murine. Utilisation dans des vaccins pour la protection du chat contre le virus de la leucémie féline.
FR7927645A 1978-12-28 1979-11-09 Preparation de glycoproteine isolee d'enveloppes d'onco-rna virus et vaccins qui la contiennent Granted FR2445338A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/973,958 US4406885A (en) 1978-12-28 1978-12-28 Preparation of native oncornavirus envelope subunits and vaccines therefrom

Publications (2)

Publication Number Publication Date
FR2445338A1 true FR2445338A1 (fr) 1980-07-25
FR2445338B1 FR2445338B1 (fr) 1983-06-17

Family

ID=25521412

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7927645A Granted FR2445338A1 (fr) 1978-12-28 1979-11-09 Preparation de glycoproteine isolee d'enveloppes d'onco-rna virus et vaccins qui la contiennent

Country Status (5)

Country Link
US (1) US4406885A (fr)
CA (1) CA1156647A (fr)
DE (1) DE2951509A1 (fr)
FR (1) FR2445338A1 (fr)
GB (1) GB2038338B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030728A2 (fr) * 1979-12-18 1981-06-24 The Ohio State University Research Foundation Vaccin contre la leucémie féline
WO1985002625A1 (fr) * 1983-12-09 1985-06-20 Cetus Corporation Vaccin du virus de la leucemie chez les felins
EP0247904A1 (fr) * 1986-05-30 1987-12-02 Cambridge Biotech Corporation Méthode de préparation et utilisation d'antigènes du virus de la leucémie des chats
US5352449A (en) * 1986-05-30 1994-10-04 Cambridge Biotech Corporation Vaccine comprising recombinant feline leukemia antigen and saponin adjuvant

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434157A (en) 1979-12-18 1984-02-28 The Ohio State University Research Foundation Method of recovering cell antigen and preparation of feline leukemia vaccine therefrom
ZA84617B (en) * 1983-02-14 1984-09-26 Arup Sen Synthetic polypeptides from viryl oncogenes
US4743678A (en) * 1983-04-27 1988-05-10 President And Fellows Of Harvard College Method and products for detection of human T cell leukemia virus
US4933179A (en) * 1983-08-22 1990-06-12 Syntex (U.S.A.) Inc. Feline leukemia virus antigen vaccines
US5152982A (en) * 1984-03-26 1992-10-06 Chiron Corporation Compositions and methods for FeLV vaccination
US4663436A (en) * 1984-04-24 1987-05-05 Scripps Clinic And Research Foundation Leukemia-associated virus immunogen, vaccine and assay
US4789702A (en) * 1984-05-18 1988-12-06 Cetus Corporation Feline leukemia virus vaccine
US5510238A (en) * 1984-10-26 1996-04-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Production of human T-cell leukemia (lymphotropic) retrovirus (HTLV-I) envelope protein fragments in bacteria and use in seroepidemiological studies
DK155886D0 (da) * 1986-04-04 1986-04-04 Bo Arne Hofmann Vaccine og fremgangsmaade til fremstilling af denne
DE68924478T2 (de) * 1988-12-13 1996-03-07 Univ Colorado Res Prototypische FeLV-Isolate für die Verwendung als Krankheitsmuster oder Impfstoffe.
EP0621893A4 (fr) * 1992-01-06 1995-07-12 Smithkline Beecham Corp Vaccins contre le virus de la leucemie des felins.
US5633234A (en) * 1993-01-22 1997-05-27 The Johns Hopkins University Lysosomal targeting of immunogens
JP4236279B2 (ja) * 1993-05-24 2009-03-11 ズィメレックス・インコーポレーテッド 異種移植に対する寛容性の発現のための代理寛容形成
EP1638587A4 (fr) 2003-02-14 2007-04-18 Univ Missouri Methodes et compositions contraceptives associees aux interferences des proteasomes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/78 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030728A2 (fr) * 1979-12-18 1981-06-24 The Ohio State University Research Foundation Vaccin contre la leucémie féline
EP0030728A3 (en) * 1979-12-18 1981-12-23 The Ohio State University Research Foundation Feline leukemia vaccine
WO1985002625A1 (fr) * 1983-12-09 1985-06-20 Cetus Corporation Vaccin du virus de la leucemie chez les felins
EP0247904A1 (fr) * 1986-05-30 1987-12-02 Cambridge Biotech Corporation Méthode de préparation et utilisation d'antigènes du virus de la leucémie des chats
US5352449A (en) * 1986-05-30 1994-10-04 Cambridge Biotech Corporation Vaccine comprising recombinant feline leukemia antigen and saponin adjuvant

Also Published As

Publication number Publication date
CA1156647A (fr) 1983-11-08
FR2445338B1 (fr) 1983-06-17
US4406885A (en) 1983-09-27
DE2951509A1 (de) 1980-07-17
GB2038338A (en) 1980-07-23
GB2038338B (en) 1982-11-24

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