FR2445328A1 - Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament - Google Patents

Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament

Info

Publication number
FR2445328A1
FR2445328A1 FR7918056A FR7918056A FR2445328A1 FR 2445328 A1 FR2445328 A1 FR 2445328A1 FR 7918056 A FR7918056 A FR 7918056A FR 7918056 A FR7918056 A FR 7918056A FR 2445328 A1 FR2445328 A1 FR 2445328A1
Authority
FR
France
Prior art keywords
oxo
derivatives
eburnane
homo
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7918056A
Other languages
English (en)
Other versions
FR2445328B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HURI000678 external-priority patent/HU178702B/hu
Priority claimed from HURI000677 external-priority patent/HU177729B/hu
Priority claimed from HURI000676 external-priority patent/HU177728B/hu
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2445328A1 publication Critical patent/FR2445328A1/fr
Application granted granted Critical
Publication of FR2445328B1 publication Critical patent/FR2445328B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Abstract

L'invention est relative à des dérivés du 14-oxo-E-éburnane. Ces composés répondent à la formule :
FR7918056A 1978-07-12 1979-07-11 Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament Granted FR2445328A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
HURI000678 HU178702B (en) 1978-07-12 1978-07-12 Process for preparing 11-bromo-vincaminic acid ester derivatives
HURI000677 HU177729B (en) 1978-07-12 1978-07-12 Process for preparing 9- and 11-bromo-e-homo-eburnan derrivatives
HURI000676 HU177728B (en) 1978-07-12 1978-07-12 Process for preparing 9- and 11-bromo-e-homo-eburnan derrivatives

Publications (2)

Publication Number Publication Date
FR2445328A1 true FR2445328A1 (fr) 1980-07-25
FR2445328B1 FR2445328B1 (fr) 1982-12-10

Family

ID=27270219

Family Applications (3)

Application Number Title Priority Date Filing Date
FR7918056A Granted FR2445328A1 (fr) 1978-07-12 1979-07-11 Derives du 14-oxo-e-homo-eburnane, leur procede de preparation et leur utilisation comme medicament
FR8004491A Granted FR2445330A1 (fr) 1978-07-12 1980-02-28 Derives du 11-bromo-14,15-dioxo-e-homo-eburnane leur preparation et leur utilisation comme medicament
FR8004490A Granted FR2445329A1 (fr) 1978-07-12 1980-02-28 Derives du 11-bromo-14-oxo-15-hydroxy-imino-e-homo-eburnane, leur preparation et leur utilisation comme medicament

Family Applications After (2)

Application Number Title Priority Date Filing Date
FR8004491A Granted FR2445330A1 (fr) 1978-07-12 1980-02-28 Derives du 11-bromo-14,15-dioxo-e-homo-eburnane leur preparation et leur utilisation comme medicament
FR8004490A Granted FR2445329A1 (fr) 1978-07-12 1980-02-28 Derives du 11-bromo-14-oxo-15-hydroxy-imino-e-homo-eburnane, leur preparation et leur utilisation comme medicament

Country Status (5)

Country Link
US (1) US4283401A (fr)
CH (1) CH649295A5 (fr)
DE (1) DE2928187A1 (fr)
FR (3) FR2445328A1 (fr)
GB (1) GB2036721B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2431496A1 (fr) * 1978-07-12 1980-02-15 Richter Gedeon Vegyeszet Procede pour la preparation d'esters d'acide 10-bromo-vincaminique et de composes analogues
FR2487836A1 (fr) * 1980-07-31 1982-02-05 Richter Gedeon Vegyeszet Nouveaux derives halogenes du 15-hydroxy-e-homoeburnane et leur procede de preparation

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428877A (en) 1978-07-12 1984-01-31 Richter Gedeon Vegyeszeti Gyar Rt. Cis-10-bromo-E-homoeburnanes
HU180928B (en) * 1979-08-06 1983-05-30 Richter Gedeon Vegyeszet Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives
HU180929B (en) * 1979-08-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing new bromo-vincamone derivatives
HU181484B (en) * 1979-10-30 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 11-bromo-15-hydroxyimino-e-homo-eburnane derivatives
HU181941B (en) * 1979-11-23 1983-11-28 Richter Gedeon Vegyeszet Process for producing apovincaminic acid ester derivatives
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
US4481204A (en) * 1983-06-29 1984-11-06 Richter Gedeon Vegyeszeti Gyar R.T. E-Homo-eburnane derivatives, process for their preparation, and pharmaceutical compositions containing these compounds
FR2713644B1 (fr) * 1993-12-14 1996-02-09 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
DE19725047A1 (de) * 1996-07-03 1998-01-08 Alsthom Cge Alcatel Erregersystem für eine Antenne mit einem parabelförmig gebogenen Reflektor und einem dielektrischen Strahler
US20050045160A1 (en) * 2003-09-03 2005-03-03 Alicia Peterson Evaporative emissions canister with incorporated liquid fuel trap

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081593A1 (en) * 1970-03-31 1971-12-10 Roussel Uclaf Vincamine process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3770724A (en) * 1970-03-31 1973-11-06 Roussel Uclaf Process for preparing pentacyclic alkaloids
FR2206090A1 (en) * 1972-11-16 1974-06-07 Omnium Chimique Sa Homovincamone-contg. medicaments - with vasodilating, spasmolytic anti-arrhythmic and anti-ischaemic properties
US4146643A (en) * 1973-12-18 1979-03-27 Sandoz Ltd. Increasing vigilance or treating cerebral insufficiency with substituted vincamines
DE2458164A1 (de) * 1973-12-18 1975-06-26 Sandoz Ag Verfahren zur herstellung von neuen heterocyclischen verbindungen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081593A1 (en) * 1970-03-31 1971-12-10 Roussel Uclaf Vincamine process

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2431496A1 (fr) * 1978-07-12 1980-02-15 Richter Gedeon Vegyeszet Procede pour la preparation d'esters d'acide 10-bromo-vincaminique et de composes analogues
FR2487836A1 (fr) * 1980-07-31 1982-02-05 Richter Gedeon Vegyeszet Nouveaux derives halogenes du 15-hydroxy-e-homoeburnane et leur procede de preparation

Also Published As

Publication number Publication date
FR2445328B1 (fr) 1982-12-10
FR2445329A1 (fr) 1980-07-25
FR2445329B1 (fr) 1983-02-25
FR2445330B1 (fr) 1983-02-25
DE2928187A1 (de) 1980-01-24
GB2036721A (en) 1980-07-02
US4283401A (en) 1981-08-11
FR2445330A1 (fr) 1980-07-25
GB2036721B (en) 1982-12-22
CH649295A5 (de) 1985-05-15

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Legal Events

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ST Notification of lapse