FR2445144B1 - - Google Patents

Info

Publication number: FR2445144B1
Authority: FR; France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR8004355A

Other versions

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Original Assignee

Farmitalia Carlo Erba SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-03-23

Filing date

1980-02-27

Publication date

1983-03-25

1980-02-27 Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL

1980-07-25 Publication of FR2445144A1 publication Critical patent/FR2445144A1/fr

1983-03-25 Application granted granted Critical

1983-03-25 Publication of FR2445144B1 publication Critical patent/FR2445144B1/fr

Status Granted legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/16—Halogen atoms; Nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FR8004355A 1978-03-23 1980-02-27 A titre de medicaments, derives de 2-hydroxymethyl-pyrazine hypolipemiants et compositions pharmaceutiques les contenant Granted FR2445144A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT21520/78A IT1094287B (it)	1978-03-23	1978-03-23	Derivati della 2-idrossimetil-pirazina aventi attivita' ipolipemizzante

Publications (2)

Publication Number	Publication Date
FR2445144A1 FR2445144A1 (fr)	1980-07-25
FR2445144B1 true FR2445144B1 (fr)	1983-03-25

Family

ID=11183025

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FR7907433A Granted FR2448536A1 (fr)	1978-03-23	1979-03-23	Nouveaux derives de 2-hydroxymethyl-pyrazine, et leur procede de preparation
FR8004355A Granted FR2445144A1 (fr)	1978-03-23	1980-02-27	A titre de medicaments, derives de 2-hydroxymethyl-pyrazine hypolipemiants et compositions pharmaceutiques les contenant

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
FR7907433A Granted FR2448536A1 (fr)	1978-03-23	1979-03-23	Nouveaux derives de 2-hydroxymethyl-pyrazine, et leur procede de preparation

Country Status (13)

Country	Link
US (1)	US4267327A (fr)
JP (1)	JPS5531063A (fr)
BE (1)	BE875013A (fr)
CA (1)	CA1146171A (fr)
CH (1)	CH642639A5 (fr)
DE (1)	DE2910824A1 (fr)
DK (1)	DK151254C (fr)
FR (2)	FR2448536A1 (fr)
GB (1)	GB2017691B (fr)
IT (1)	IT1094287B (fr)
NL (1)	NL7902268A (fr)
SE (1)	SE446338B (fr)
ZA (1)	ZA791047B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4406901A (en) *	1980-02-06	1983-09-27	Farmitalia Carlo Erba S.P.A.	Ethers of substituted hydroxymethylpyrazines
IL64267A (en) *	1980-12-09	1985-08-30	Erba Farmitalia	Ethers of hydroxymethylpyrazin-n-oxides,their preparation and pharmaceutical compositions containing them
JPS59219269A (ja) *	1983-05-30	1984-12-10	Terumo Corp	ピラジン誘導体を有効成分とする血小板凝集抑制剤
DE3433960A1 (de) *	1984-09-15	1986-03-27	Basf Ag, 6700 Ludwigshafen	Verfahren zur herstellung von 2-amino-3-cyano-5-dialkoxymehtyl-pyrazinen und zwischenprodukte fuer diese verfahren
JPS63135216U (fr) *	1987-02-27	1988-09-05
CN101684102B (zh) *	2008-09-28	2013-06-05	安徽省新星药物开发有限责任公司	苯氧乙酸吡嗪酯类衍生物及其制法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU470007B2 (en) *	1972-04-28	1976-02-26	Farmitalia Carlo Erba S.R.L.	Pyrazine 4-oxide derivatives and process for their preparation
US4002750A (en) *	1972-04-28	1977-01-11	Carlo Erba S.P.A.	Pyrazine 4-oxide derivatives and process for their preparation
US4051245A (en) *	1972-04-28	1977-09-27	Carlo Erba, S.P.A.	Pyrazine 4-oxide derivatives and process for their preparation

1978
- 1978-03-23 IT IT21520/78A patent/IT1094287B/it active
1979
- 1979-02-26 US US06/015,223 patent/US4267327A/en not_active Expired - Lifetime
- 1979-03-06 ZA ZA791047A patent/ZA791047B/xx unknown
- 1979-03-20 CH CH261779A patent/CH642639A5/de not_active IP Right Cessation
- 1979-03-20 DE DE19792910824 patent/DE2910824A1/de active Granted
- 1979-03-21 GB GB7909897A patent/GB2017691B/en not_active Expired
- 1979-03-22 DK DK118879A patent/DK151254C/da not_active IP Right Cessation
- 1979-03-22 CA CA000323983A patent/CA1146171A/fr not_active Expired
- 1979-03-22 NL NL7902268A patent/NL7902268A/xx not_active Application Discontinuation
- 1979-03-22 BE BE0/194146A patent/BE875013A/fr not_active IP Right Cessation
- 1979-03-23 FR FR7907433A patent/FR2448536A1/fr active Granted
- 1979-03-23 SE SE7902661A patent/SE446338B/sv not_active IP Right Cessation
- 1979-03-23 JP JP3340479A patent/JPS5531063A/ja active Granted
1980
- 1980-02-27 FR FR8004355A patent/FR2445144A1/fr active Granted

Also Published As

Publication number	Publication date
DK151254B (da)	1987-11-16
IT7821520A0 (it)	1978-03-23
US4267327A (en)	1981-05-12
DK151254C (da)	1988-07-04
DK118879A (da)	1979-09-24
NL7902268A (nl)	1979-09-25
CH642639A5 (de)	1984-04-30
GB2017691B (en)	1982-06-16
JPS6310697B2 (fr)	1988-03-08
DE2910824A1 (de)	1979-09-27
FR2448536A1 (fr)	1980-09-05
CA1146171A (fr)	1983-05-10
SE7902661L (sv)	1979-09-24
SE446338B (sv)	1986-09-01
DE2910824C2 (fr)	1989-06-22
FR2448536B1 (fr)	1983-01-28
BE875013A (fr)	1979-09-24
JPS5531063A (en)	1980-03-05
ZA791047B (en)	1980-03-26
GB2017691A (en)	1979-10-10
FR2445144A1 (fr)	1980-07-25
IT1094287B (it)	1985-07-26

Legal Events

Date	Code	Title	Description
1988-08-05	TP	Transmission of property
1994-01-28	ST	Notification of lapse

Publication	Publication Date	Title
FR2415735B1 (fr)	1985-03-22
FR2415115B1 (fr)	1983-05-06
FR2416920B1 (fr)	1983-07-18
FR2414328B1 (fr)	1984-11-09
FR2414406B1 (fr)	1984-02-24
FR2415126B1 (fr)	1983-07-18
FR2416605B1 (fr)	1985-05-17
FR2414845B1 (fr)	1983-05-27
FR2415598B1 (fr)	1980-08-29
DE2857623T1 (fr)	1981-03-12
FR2415281B1 (fr)	1982-05-14
FR2413041B1 (fr)	1981-08-14
FR2415992B1 (fr)	1982-12-10
DK141792C (fr)	1980-11-03
BG26007A1 (fr)	1979-02-15
BG25956A1 (fr)	1979-01-12
BG26022A1 (fr)	1979-02-15
BG26017A1 (fr)	1979-02-15
BG26015A1 (fr)	1979-02-15
BG26014A1 (fr)	1979-02-15
BG26013A1 (fr)	1979-02-15
BG26012A1 (fr)	1979-02-15
BG26009A1 (fr)	1979-02-15
BG26008A1 (fr)	1979-02-15
BG25917A1 (fr)	1979-01-12