FR2424917A1 - Nouvelles 4-quinolinylaminobenzoyl-piperidines, leur procede de production et medicament les contenant - Google Patents

Nouvelles 4-quinolinylaminobenzoyl-piperidines, leur procede de production et medicament les contenant

Info

Publication number
FR2424917A1
FR2424917A1 FR7911262A FR7911262A FR2424917A1 FR 2424917 A1 FR2424917 A1 FR 2424917A1 FR 7911262 A FR7911262 A FR 7911262A FR 7911262 A FR7911262 A FR 7911262A FR 2424917 A1 FR2424917 A1 FR 2424917A1
Authority
FR
France
Prior art keywords
group
quinolinylaminobenzoyl
piperidines
news
production process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7911262A
Other languages
English (en)
Other versions
FR2424917B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2424917A1 publication Critical patent/FR2424917A1/fr
Application granted granted Critical
Publication of FR2424917B1 publication Critical patent/FR2424917B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

L'INVENTION A TRAIT AU DOMAINE DE LA CHIMIE PHARMACEUTIQUE. ELLE CONCERNE DES COMPOSES DE FORMULE: (CF DESSIN DANS BOPI) (DANS LAQUELLE D EST UN NOYAU PIPERIDINO OU 1,2,5,6-TETRAHYDROPIRIDINO; X REPRESENTE C1 OU UN GROUPE -CF; R REPRESENTE H OU UN GROUPE -OH LORSQUE D EST UN NOYAU PIPERIDINO OU NE REPRESENTE RIEN LORSQUE D EST UN GROUPE 1,2,5,6-TETRAHYDROPYRIDINO; ET AR EST UN GROUPE 2-OXO-1-BENZIMIDAZOLINYLE, PHENYLE OU PHENYLE SUBSTITUE) ET LEURS SELS D'ADDITION D'ACIDES ACCEPTABLES DU POINT DE VUE PHARMACOLOGIQUE. ELLE CONCERNE EGALEMENT LA PREPARATION DE CES COMPOSES. LES COMPOSES DE L'INVENTION ET LEURS SELS D'ADDITION D'ACIDES ACCEPTABLES DU POINT DE VUE PHARMACOLOGIQUE SONT DOUES DE PROPRIETES ANTI-HYPERTENSIVES.
FR7911262A 1978-05-05 1979-05-04 Nouvelles 4-quinolinylaminobenzoyl-piperidines, leur procede de production et medicament les contenant Granted FR2424917A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/903,088 US4166853A (en) 1978-05-05 1978-05-05 Antihypertensive 7-trifluoromethyl-4-aminoquinolones

Publications (2)

Publication Number Publication Date
FR2424917A1 true FR2424917A1 (fr) 1979-11-30
FR2424917B1 FR2424917B1 (fr) 1983-01-14

Family

ID=25416923

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7911262A Granted FR2424917A1 (fr) 1978-05-05 1979-05-04 Nouvelles 4-quinolinylaminobenzoyl-piperidines, leur procede de production et medicament les contenant

Country Status (9)

Country Link
US (1) US4166853A (fr)
JP (1) JPS54145676A (fr)
AU (1) AU521628B2 (fr)
BE (1) BE876042A (fr)
DE (1) DE2914511A1 (fr)
FR (1) FR2424917A1 (fr)
GB (1) GB2021103B (fr)
IT (1) IT1113370B (fr)
NL (1) NL7903437A (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886795A (en) * 1984-06-20 1989-12-12 Schachar Ronald A Treatment and prevention of retinal edema with dopaminergic antagonists
US4624957A (en) * 1984-06-20 1986-11-25 Schachar Ronald A Treatment and prevention of retinal edema with dopaminergic antagonists
US4886815A (en) * 1984-06-20 1989-12-12 Schachar Ronald A Treatment and prevention of retinal edema with dopaminergic antagonists
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
WO1995003298A1 (fr) * 1993-07-19 1995-02-02 Fujisawa Pharmaceutical Co., Ltd. DERIVES BENZIMIDAZOLIQUES UTILISABLES COMME AGONISTE DU RECEPTEUR DOPAMINERGIQUE, ANTAGONISTE DU RECEPTEUR SEROTONINERGIQUE, OU ANTAGONISTE DU RECEPTEUR α¿1?
KR20010113007A (ko) * 2000-06-15 2001-12-24 주정호 항암제로서 유용한 ｎ-치환된 피페리디닐우레아 유도체 및그의 제조방법
US20060293298A1 (en) * 2003-04-10 2006-12-28 Bamford Mark J Compounds
GB0308333D0 (en) * 2003-04-10 2003-05-14 Glaxo Group Ltd Novel compounds
AR058558A1 (es) * 2005-12-21 2008-02-13 Schering Corp Derivados de anilina sustituida utiles como antagonistas de la histamina h3
MX2008011791A (es) * 2006-03-15 2008-09-25 Wyeth Corp Azaciclilaminas-n-sustituidas como antagonistas de histamina-3.
CN101432261A (zh) * 2006-05-19 2009-05-13 惠氏公司 作为组织胺-3拮抗剂的n-苯甲酰基-吡咯烷-3-基胺和n-苄基-吡咯烷-3-基胺
PE20081152A1 (es) * 2006-10-06 2008-08-10 Wyeth Corp Azaciclilaminas n-sustituidas como antagonistas de histamina-3
MX2009012734A (es) * 2007-05-24 2010-03-30 Wyeth Llc Derivados de azaciclilbenzamida como antagonistas de histamina-3.
CA2693138A1 (fr) 2007-07-16 2009-01-22 Wyeth Llc Derives d'aminoalkylazole en tant qu'antagonistes d'histamine-3
TW200918062A (en) * 2007-09-12 2009-05-01 Wyeth Corp Azacyclylisoquinolinone and-isoindolinone derivatives as histamine-3 antagonists
KR20100054856A (ko) * 2007-09-12 2010-05-25 와이어쓰 엘엘씨 히스타민-3 길항제로서의 이소퀴놀리닐 및 이소인돌리닐 유도체

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875165A (en) * 1973-02-22 1975-04-01 Wyeth John & Brother Ltd (4-Quinolylamino)-(N-piperidyl)benzamides and N-{8 (quinolylamino)-benzoyl{9 piperidines
US4025629A (en) * 1974-01-07 1977-05-24 The Upjohn Company P-(trifluoromethylquinolylamino)benzamides, pharmaceutical dosage forms and method of treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754586A (fr) * 1969-08-08 1971-02-08 Upjohn Co Preparations pharmaceutiques a base de p-(4-quinolylamino) benzamide etleur utilisation
US3971787A (en) * 1973-02-05 1976-07-27 John Wyeth & Brother Limited (4-Quinolylamino)benzamides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3875165A (en) * 1973-02-22 1975-04-01 Wyeth John & Brother Ltd (4-Quinolylamino)-(N-piperidyl)benzamides and N-{8 (quinolylamino)-benzoyl{9 piperidines
US4025629A (en) * 1974-01-07 1977-05-24 The Upjohn Company P-(trifluoromethylquinolylamino)benzamides, pharmaceutical dosage forms and method of treatment

Also Published As

Publication number Publication date
GB2021103B (en) 1982-08-11
IT7922088A0 (it) 1979-04-23
DE2914511A1 (de) 1979-11-08
BE876042A (fr) 1979-11-05
FR2424917B1 (fr) 1983-01-14
IT1113370B (it) 1986-01-20
GB2021103A (en) 1979-11-28
NL7903437A (nl) 1979-11-07
AU521628B2 (en) 1982-04-22
US4166853A (en) 1979-09-04
AU4642179A (en) 1979-11-08
JPS54145676A (en) 1979-11-14

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Legal Events

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