FR2381762A1 - Dibenzodiazepines utilisables comme antischizophreniques - Google Patents

Dibenzodiazepines utilisables comme antischizophreniques

Info

Publication number
FR2381762A1
FR2381762A1 FR7805100A FR7805100A FR2381762A1 FR 2381762 A1 FR2381762 A1 FR 2381762A1 FR 7805100 A FR7805100 A FR 7805100A FR 7805100 A FR7805100 A FR 7805100A FR 2381762 A1 FR2381762 A1 FR 2381762A1
Authority
FR
France
Prior art keywords
dibenzodiazepines
antischizophrenics
novel
formula
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7805100A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of FR2381762A1 publication Critical patent/FR2381762A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne de nouvelles dibenzodiazépines. Les dibenzodiazépines de l'invention répondent à la formule :
FR7805100A 1977-02-23 1978-02-22 Dibenzodiazepines utilisables comme antischizophreniques Withdrawn FR2381762A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/771,215 US4096261A (en) 1977-02-23 1977-02-23 Dibenzodiazepines

Publications (1)

Publication Number Publication Date
FR2381762A1 true FR2381762A1 (fr) 1978-09-22

Family

ID=25091082

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7805100A Withdrawn FR2381762A1 (fr) 1977-02-23 1978-02-22 Dibenzodiazepines utilisables comme antischizophreniques

Country Status (5)

Country Link
US (1) US4096261A (fr)
JP (1) JPS53105488A (fr)
DE (1) DE2807569A1 (fr)
FR (1) FR2381762A1 (fr)
GB (1) GB1561551A (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2491470A1 (fr) * 1980-10-08 1982-04-09 Innothera Lab Sa Nouvelles cyclopropylmethyl piperazines, leur procede de preparation et leur application en therapeutique
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
WO1991010661A1 (fr) * 1990-01-11 1991-07-25 Novokuznetsky Nauchno-Issledovatelsky Khimiko-Farmatsevtichesky Institut DERIVES DE 5-AMINO-8-CHLORE-DIBENZO[b,e][1,4]-DIAZEPINE ET PREPARATION PHARMACEUTIQUE DE TRAITEMENT DE L'EPILEPSIE AINSI QUE D'ETATS EPILEPTIQUES A BASE DESDITS DERIVES
US5538965A (en) * 1993-12-23 1996-07-23 Allelix Biopharmaceuticals Inc. Dopamine receptor ligands
US5576314A (en) * 1994-12-12 1996-11-19 Allelix Biopharmaceuticals Inc. Bicyclic nonane and decane compounds having dopamine receptor affinity
US5602120A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. Benzyl-substituted compounds having dopamine receptor affinity
US5700445A (en) * 1994-12-12 1997-12-23 Allelix Biopharmaceuticals, Inc. N-methyl piperazine compounds having dopamine receptor affinity
US5602121A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. Alkyl-substituted compounds having dopamine receptor affinity
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
US20050250767A1 (en) * 2003-01-23 2005-11-10 Weiner David M Use of N-desmethylclozapine to treat human neuropsychiatric disease
JP2006515628A (ja) * 2003-01-23 2006-06-01 アカディア ファーマシューティカルズ，インコーポレーテッド ヒト神経精神疾患を処置するためのｎ−デスメチルクロザピンの使用
US20050085463A1 (en) * 2003-01-23 2005-04-21 Weiner David M. Use of N-desmethylclozapine to treat human neuropsychiatric disease
CN1913900B (zh) * 2003-12-22 2010-11-24 阿卡蒂亚药品公司 作为毒蕈碱激动剂的氨基取代的二芳基[a，d]环庚烯类似物及神经精神疾病的治疗方法
SG133606A1 (en) * 2003-12-22 2007-07-30 Acadia Pharm Inc Amino substituted diaryl [a,d] cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders
CA2560671A1 (fr) * 2004-04-01 2006-01-05 Acadia Pharmaceuticals Inc. Synthese et isolation de n-demethylclozapine et formes cristallines correspondantes
US20070105836A1 (en) * 2005-10-31 2007-05-10 Lars Pettersson Prodrugs of muscarinic agonists and methods of treatment of neuropsychiatric disorders

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3793325A (en) * 1967-03-22 1974-02-19 Sandoz Ag 11-basically substituted dibenz(b,f)(1,4)thiazepine and dibenz(b,e)(1,4)diazepines

Also Published As

Publication number Publication date
GB1561551A (en) 1980-02-20
JPS53105488A (en) 1978-09-13
DE2807569A1 (de) 1978-08-24
US4096261A (en) 1978-06-20

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Legal Events

Date Code Title Description
ST Notification of lapse