FR2342976A1 - Cyanoalkylureidocephalosporines, utiles comme agents antibacteriens - Google Patents

Cyanoalkylureidocephalosporines, utiles comme agents antibacteriens

Info

Publication number
FR2342976A1
FR2342976A1 FR7706446A FR7706446A FR2342976A1 FR 2342976 A1 FR2342976 A1 FR 2342976A1 FR 7706446 A FR7706446 A FR 7706446A FR 7706446 A FR7706446 A FR 7706446A FR 2342976 A1 FR2342976 A1 FR 2342976A1
Authority
FR
France
Prior art keywords
cyanoalkylureidocephalosporins
useful
antibacterial agents
antibacterial
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7706446A
Other languages
English (en)
Other versions
FR2342976B1 (fr
Inventor
Hermann Breuer
Uwe D Treuner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2342976A1 publication Critical patent/FR2342976A1/fr
Application granted granted Critical
Publication of FR2342976B1 publication Critical patent/FR2342976B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR7706446A 1976-03-05 1977-03-04 Cyanoalkylureidocephalosporines, utiles comme agents antibacteriens Granted FR2342976A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66412876A 1976-03-05 1976-03-05

Publications (2)

Publication Number Publication Date
FR2342976A1 true FR2342976A1 (fr) 1977-09-30
FR2342976B1 FR2342976B1 (fr) 1980-06-27

Family

ID=24664650

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7706446A Granted FR2342976A1 (fr) 1976-03-05 1977-03-04 Cyanoalkylureidocephalosporines, utiles comme agents antibacteriens

Country Status (14)

Country Link
US (1) US4096329A (fr)
JP (1) JPS52108995A (fr)
AU (1) AU508629B2 (fr)
BE (1) BE852090A (fr)
CA (1) CA1109460A (fr)
DE (1) DE2707490A1 (fr)
DK (1) DK97177A (fr)
FR (1) FR2342976A1 (fr)
GB (1) GB1574791A (fr)
NL (1) NL7702121A (fr)
NO (1) NO770757L (fr)
NZ (1) NZ183272A (fr)
SE (1) SE7702481L (fr)
ZA (1) ZA77717B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59104389A (ja) * 1982-12-06 1984-06-16 Shionogi & Co Ltd オキサセファム誘導体
JPH0712404U (ja) * 1993-08-09 1995-02-28 有限会社杜の會 生理用フレアーパンツ
CN102675342A (zh) * 2011-03-15 2012-09-19 四平市精细化学品有限公司 7β-氨基-7α-甲氧基-3-[（1-甲基-1H-四唑-5-基）硫甲基]-3-头孢烯-4-羧酸二苯甲酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2309599A1 (de) * 1973-02-26 1974-09-05 Bayer Ag Verfahren zur herstellung von 7-acylamino-desacetoxy-cephalosporansaeurederivaten
US3996217A (en) * 1975-09-08 1976-12-07 E. R. Squibb & Sons, Inc. 3-Triazolylthio derivatives of ureido cephalosporins

Also Published As

Publication number Publication date
GB1574791A (en) 1980-09-10
JPS52108995A (en) 1977-09-12
ZA77717B (en) 1977-12-28
SE7702481L (sv) 1977-10-17
DK97177A (da) 1977-09-06
NZ183272A (en) 1979-03-28
US4096329A (en) 1978-06-20
FR2342976B1 (fr) 1980-06-27
AU508629B2 (en) 1980-03-27
NL7702121A (nl) 1977-09-07
DE2707490A1 (de) 1977-09-08
CA1109460A (fr) 1981-09-22
BE852090A (fr) 1977-09-05
NO770757L (no) 1977-09-06
AU2209077A (en) 1978-08-17

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Legal Events

Date Code Title Description
ST Notification of lapse