FR2336412A1 - Procede nouveau de synthese de la 3', 4'-didesoxykanamycine b'' - Google Patents

Procede nouveau de synthese de la 3', 4'-didesoxykanamycine b''

Info

Publication number
FR2336412A1
FR2336412A1 FR7637816A FR7637816A FR2336412A1 FR 2336412 A1 FR2336412 A1 FR 2336412A1 FR 7637816 A FR7637816 A FR 7637816A FR 7637816 A FR7637816 A FR 7637816A FR 2336412 A1 FR2336412 A1 FR 2336412A1
Authority
FR
France
Prior art keywords
didesoxykanamycin
synthesis
new process
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7637816A
Other languages
English (en)
Other versions
FR2336412B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of FR2336412A1 publication Critical patent/FR2336412A1/fr
Application granted granted Critical
Publication of FR2336412B1 publication Critical patent/FR2336412B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FR7637816A 1975-12-11 1976-12-08 Procede nouveau de synthese de la 3', 4'-didesoxykanamycine b'' Granted FR2336412A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP50146903A JPS6029720B2 (ja) 1975-12-11 1975-12-11 ３′，４′‐ジデオキシカナマイシンｂの新規な製造法

Publications (2)

Publication Number Publication Date
FR2336412A1 true FR2336412A1 (fr) 1977-07-22
FR2336412B1 FR2336412B1 (fr) 1980-09-26

Family

ID=15418164

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7637816A Granted FR2336412A1 (fr) 1975-12-11 1976-12-08 Procede nouveau de synthese de la 3', 4'-didesoxykanamycine b''

Country Status (11)

Country Link
US (1) US4156078A (fr)
JP (1) JPS6029720B2 (fr)
BE (1) BE849311A (fr)
CA (1) CA1075684A (fr)
DE (1) DE2655731C3 (fr)
DK (1) DK159787C (fr)
FR (1) FR2336412A1 (fr)
GB (1) GB1555661A (fr)
HU (1) HU176356B (fr)
NL (1) NL7613706A (fr)
YU (3) YU41292B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6052719B2 (ja) * 1976-12-16 1985-11-20 財団法人微生物化学研究会 ３′，４′−ジデオキシカナマイシンｂの新規な製造法
JPS5581897A (en) * 1978-12-14 1980-06-20 Microbial Chem Res Found Preparation of 1-n-isoseryl-or 1-n-(l-4-amino-2-hydroxybutyryl)-3',4'-dideoxykanamycin b
JPS55105699A (en) * 1979-02-05 1980-08-13 Microbial Chem Res Found 3',4'-dideoxykanamycin a and its 1-n-aminoalkanoyl derivative
JPS5643297A (en) * 1979-09-19 1981-04-21 Microbial Chem Res Found 6"-deoxydibeckacin or 4",6"-dideoxydibeckacin, their 1-n-acyl derivative, and their preparation
JPS5663993A (en) * 1979-10-30 1981-05-30 Microbial Chem Res Found Novel preparation of tobramycin
US4438109A (en) 1980-07-25 1984-03-20 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Tylosin derivatives
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin
US5488038A (en) * 1992-11-27 1996-01-30 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Dibekacin derivatives and arbekacin derivatives active against resistant bacteria
CN101575354B (zh) * 2009-05-26 2013-03-13 北京化工大学 阿贝卡星及其中间体地贝卡星的合成方法
CN102786564B (zh) * 2011-05-19 2015-05-13 北京化工大学 阿贝卡星及其中间体地贝卡星的合成新方法
CN106946957B (zh) * 2017-05-11 2019-11-08 常州方圆制药有限公司 阿贝卡星中间体的制备方法
JP7271519B2 (ja) * 2017-06-05 2023-05-11 エロックス ファーマシューティカルズ リミテッド アミノグリコシド誘導体及び遺伝子疾患の治療におけるその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1349302A (en) * 1970-07-29 1974-04-03 Microbial Chem Res Found 3,-4,-dideoxykanamycin b active against resistant bacteria and its synthesis
US3929762A (en) * 1972-08-23 1975-12-30 Microbial Chem Res Found 3{40 -Deoxy derivatives of neamine and its related aminoglycosidic antibiotics, and the production thereof
US3868360A (en) * 1972-10-24 1975-02-25 Schering Corp Process for preparing 2-deroxy-3-desamino-2,3-epimino-aminoglycosides and intermediates useful therein

Also Published As

Publication number Publication date
DE2655731C3 (de) 1982-04-29
DE2655731A1 (de) 1977-06-23
DK159787B (da) 1990-12-03
YU42084B (en) 1988-04-30
JPS5271446A (en) 1977-06-14
HU176356B (en) 1981-01-28
FR2336412B1 (fr) 1980-09-26
DK554076A (da) 1977-06-12
YU42129B (en) 1988-04-30
YU299776A (en) 1982-06-30
BE849311A (fr) 1977-06-10
YU146385A (en) 1986-06-30
JPS6029720B2 (ja) 1985-07-12
GB1555661A (en) 1979-11-14
YU146285A (en) 1986-06-30
YU41292B (en) 1987-02-28
DE2655731B2 (de) 1981-08-06
CA1075684A (fr) 1980-04-15
NL7613706A (nl) 1977-06-14
US4156078A (en) 1979-05-22
DK159787C (da) 1991-04-22

Similar Documents

Publication Publication Date Title
RO68479A (fr) Procede pour la preparation des 1,4-dihydropyridinecarboxylates d'aralkyle
FR2312501A1 (fr) Procede de synthese de composes de la serie des vinblastine-vincristine
BE838754A (fr) Procede ameliore pour la preparation de dimethylol-2, 2-alcanals
RO69608A (fr) Procede pour la preparation des 1,2-benzisothiazole-3-ones
FR2335507A1 (fr) Procede de production d'intermediaires de synthese de dibenzo(b,d)pyranes
FR2300795A1 (fr) Procede de synthese
PT65602B (fr) Nouveau procede de preparation d'azines
FR2336412A1 (fr) Procede nouveau de synthese de la 3', 4'-didesoxykanamycine b''
FR2326409A2 (fr) Procede de preparation d'arylamines
BE838823A (fr) Procede pour la preparation de 1,2,5-dihydroxycholecalciferol
FR2335522A1 (fr) Procede de preparation d'androstene-4 diones-3,17
BE849245A (fr) Procede de synthese des penicillines
RO64606A (fr) Procede pour la preparation des 6-methylergolines-8,8-disubstituees
FR2314192A1 (fr) Procede de preparation d'oxaphospholannes-1,2
RO76667A (fr) Procede pour la preparation des 2,4-dialkyamino-6-chlore-5-triazines
BE844259A (fr) Procede de preparation d'aldehydes &,b-ethyleniques
BE845327A (fr) Procede de preparation de 4,4'-dihydroxy-3-3'-5-5'-tretralcoyldiphenylalcanes
FR2332976A1 (fr) Procede de preparation de diaryl-1,3 triazenes
FR2319615A1 (fr) Procede de preparation de cyclohexane-diones-1,3
RO70232A (fr) Procede pour la preparation des 4-pyrazolile-4h-1,2,4-triazolile
BE852700R (fr) Procede de preparation d'oxaphospholannes-1,2
BE842471A (fr) Nouveau procede de synthese de l'acide m-benzoylhydratropique
FR2318166A1 (fr) Procede de preparation continue de 2,5-dioxo-1-oxa-2-phospholanes
FR2342270A1 (fr) Procede de preparation de 1,2-cycloalcanediones par auto-oxydation de cycloalcanones
FR2317307A1 (fr) Procede de preparation d'oxaphospholannes-1,2