FR22C1021I1 - Régime posologique pour ponesimod, un agoniste du récepteur s1p1 sélectif - Google Patents

Régime posologique pour ponesimod, un agoniste du récepteur s1p1 sélectif

Info

Publication number
FR22C1021I1
FR22C1021I1 FR22C1021C FR22C1021C FR22C1021I1 FR 22C1021 I1 FR22C1021 I1 FR 22C1021I1 FR 22C1021 C FR22C1021 C FR 22C1021C FR 22C1021 C FR22C1021 C FR 22C1021C FR 22C1021 I1 FR22C1021 I1 FR 22C1021I1
Authority
FR
France
Prior art keywords
ponesimod
selective
receptor agonist
dosage regimen
regimen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR22C1021C
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Actelion Pharmaceuticals Ltd
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54843844&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR22C1021(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of FR22C1021I1 publication Critical patent/FR22C1021I1/fr
Application granted granted Critical
Publication of FR22C1021I2 publication Critical patent/FR22C1021I2/fr
Active legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54Nitrogen and either oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/14Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
FR22C1021C 2014-12-11 2022-06-01 Régime posologique pour ponesimod, un agoniste du récepteur s1p1 sélectif Active FR22C1021I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2014077469 2014-12-11
EP2015058202 2015-04-15
PCT/EP2015/079208 WO2016091996A1 (fr) 2014-12-11 2015-12-10 Régime posologique pour un agoniste de récepteur s1p1 sélectif

Publications (2)

Publication Number Publication Date
FR22C1021I1 true FR22C1021I1 (fr) 2022-07-15
FR22C1021I2 FR22C1021I2 (fr) 2023-04-14

Family

ID=54843844

Family Applications (1)

Application Number Title Priority Date Filing Date
FR22C1021C Active FR22C1021I2 (fr) 2014-12-11 2022-06-01 Régime posologique pour ponesimod, un agoniste du récepteur s1p1 sélectif

Country Status (31)

Country Link
US (4) US10220023B2 (fr)
EP (2) EP3256125B1 (fr)
JP (1) JP6244497B1 (fr)
KR (4) KR102427123B1 (fr)
CN (2) CN117137912A (fr)
AU (2) AU2015359346B2 (fr)
CA (1) CA2968180C (fr)
CL (1) CL2017001457A1 (fr)
CY (1) CY1125170T1 (fr)
DK (1) DK3256125T3 (fr)
EA (1) EA036075B1 (fr)
ES (1) ES2909071T3 (fr)
FR (1) FR22C1021I2 (fr)
HR (1) HRP20220359T8 (fr)
HU (2) HUE057865T2 (fr)
IL (1) IL252727B (fr)
LT (2) LT3256125T (fr)
MX (2) MX2020011182A (fr)
MY (1) MY188764A (fr)
NL (1) NL301174I2 (fr)
NO (1) NO2022023I1 (fr)
PH (1) PH12017501059A1 (fr)
PL (1) PL3256125T3 (fr)
PT (1) PT3256125T (fr)
RS (1) RS63048B1 (fr)
SG (1) SG11201704563RA (fr)
SI (1) SI3256125T1 (fr)
TW (1) TW201625242A (fr)
UA (1) UA122064C2 (fr)
WO (1) WO2016091996A1 (fr)
ZA (1) ZA201704624B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009227629B2 (en) 2008-03-17 2014-09-04 Actelion Pharmaceuticals Ltd Dosing regimen for a selective S1P1 receptor agonist
MA41139A (fr) 2014-12-11 2017-10-17 Actelion Pharmaceuticals Ltd Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1
WO2016091996A1 (fr) 2014-12-11 2016-06-16 Actelion Pharmaceuticals Ltd Régime posologique pour un agoniste de récepteur s1p1 sélectif
JOP20190207A1 (ar) * 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
CA3145269A1 (fr) 2019-07-22 2021-01-28 Michel BURCKLEN Utilisation du ponesimod dans le traitement de la sclerose en plaques
EP4051250A1 (fr) 2019-10-31 2022-09-07 Idorsia Pharmaceuticals Ltd Combinaison d'un antagoniste de cxcr7 avec un modulateur du récepteur s1p1
BR112022017754A2 (pt) 2020-03-06 2022-10-18 Actelion Pharmaceuticals Ltd Métodos para retardar a perda de volume cerebral
BR112023018841A2 (pt) 2021-03-17 2023-12-26 Actelion Pharmaceuticals Ltd Sistema de dosagem farmacêutica
CA3220723A1 (fr) 2021-10-11 2023-04-20 Allitia DIBERNARDO Methodes de traitement de la sclerose en plaques
WO2023061935A1 (fr) 2021-10-11 2023-04-20 Actelion Pharmaceuticals Ltd Méthodes de traitement de la sclérose en plaques
WO2023062511A1 (fr) 2021-10-11 2023-04-20 Actelion Pharmaceuticals Ltd Méthodes de traitement de la sclérose en plaques
WO2023061918A1 (fr) 2021-10-11 2023-04-20 Actelion Pharmaceuticals Ltd Méthodes de traitement de la sclérose en plaques
WO2023079079A1 (fr) 2021-11-05 2023-05-11 Actelion Pharmaceuticals Ltd Méthodes de traitement de la sclérose en plaques
CA3220702A1 (fr) 2022-02-11 2023-08-17 Actelion Pharmaceuticals Ltd Methodes de ralentissement d'une augmentation du volume ventriculaire cerebral

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0217152D0 (en) 2002-07-24 2002-09-04 Novartis Ag Organic compounds
USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
CN100567275C (zh) 2003-11-21 2009-12-09 埃科特莱茵药品有限公司 作为免疫抑制剂的5-(苯基-(z)-亚基)-噻唑烷-4-酮衍生物
KR20070085465A (ko) 2004-11-29 2007-08-27 노파르티스 아게 S1p 수용체 효능제의 투여 용법
US7879821B2 (en) 2006-01-26 2011-02-01 University Of Medicine And Dentistry Of New Jersey Method for modulating inflammatory responses by altering plasma lipid levels
MX2009005048A (es) 2006-11-23 2009-05-25 Actelion Pharmaceuticals Ltd Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona.
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
AU2009227629B2 (en) 2008-03-17 2014-09-04 Actelion Pharmaceuticals Ltd Dosing regimen for a selective S1P1 receptor agonist
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
SI2379069T1 (sl) 2008-12-22 2015-07-31 Novartis Ag Režim odmerjanja agonista receptorja S1P
ES2760607T3 (es) 2008-12-22 2020-05-14 Novartis Ag Régimen de dosificación para un agonista del receptor s1p
JP6322630B2 (ja) 2012-08-17 2018-05-09 アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd (2Z,5Z)−5−(3−クロロ−4−((R)−2,3−ジヒドロキシプロポキシ)ベンジリデン)−2−(プロピルイミノ)−3−(o−トリル)チアゾリジン−4−オンの製造方法及び前記方法において使用される中間体
MA41139A (fr) 2014-12-11 2017-10-17 Actelion Pharmaceuticals Ltd Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1
WO2016091996A1 (fr) * 2014-12-11 2016-06-16 Actelion Pharmaceuticals Ltd Régime posologique pour un agoniste de récepteur s1p1 sélectif

Also Published As

Publication number Publication date
ZA201704624B (en) 2022-03-30
DK3256125T3 (da) 2022-03-21
CA2968180C (fr) 2020-01-28
LT3256125T (lt) 2022-04-11
EA201791286A1 (ru) 2017-12-29
SI3256125T1 (sl) 2022-04-29
WO2016091996A1 (fr) 2016-06-16
NO2022023I1 (no) 2022-06-10
JP6244497B1 (ja) 2017-12-06
NZ768672A (en) 2023-10-27
NL301174I2 (nl) 2022-06-09
HRP20220359T1 (hr) 2022-05-13
HUE057865T2 (hu) 2022-06-28
US20230131600A1 (en) 2023-04-27
SG11201704563RA (en) 2017-07-28
CY1125170T1 (el) 2022-07-22
UA122064C2 (uk) 2020-09-10
AU2015359346B2 (en) 2020-05-07
KR102590068B1 (ko) 2023-10-16
US20170319555A1 (en) 2017-11-09
AU2020202684A1 (en) 2020-05-14
EP3256125A1 (fr) 2017-12-20
IL252727B (en) 2021-02-28
ES2909071T3 (es) 2022-05-05
HUS2200021I1 (hu) 2022-05-28
RS63048B1 (sr) 2022-04-29
EP3256125B1 (fr) 2022-01-26
AU2015359346A8 (en) 2017-08-03
KR20210126792A (ko) 2021-10-20
NZ733463A (en) 2023-10-27
US11771683B2 (en) 2023-10-03
NL301174I1 (fr) 2022-05-09
KR20230147768A (ko) 2023-10-23
AU2015359346A1 (en) 2017-07-27
US10220023B2 (en) 2019-03-05
US20180147188A9 (en) 2018-05-31
TW201625242A (zh) 2016-07-16
CN117137912A (zh) 2023-12-01
FR22C1021I2 (fr) 2023-04-14
EP4056179A1 (fr) 2022-09-14
PT3256125T (pt) 2022-05-06
IL252727A0 (en) 2017-08-31
MX2020011182A (es) 2022-10-03
EA036075B1 (ru) 2020-09-23
PL3256125T3 (pl) 2022-05-09
KR102427123B1 (ko) 2022-07-28
MX2017007638A (es) 2017-09-11
US20190151292A1 (en) 2019-05-23
KR20170094335A (ko) 2017-08-17
JP2017538706A (ja) 2017-12-28
KR20200013086A (ko) 2020-02-05
PH12017501059A1 (en) 2017-11-27
CL2017001457A1 (es) 2018-02-09
HRP20220359T8 (hr) 2022-05-27
CN106999461A (zh) 2017-08-01
US20210052555A1 (en) 2021-02-25
US10857134B2 (en) 2020-12-08
MY188764A (en) 2021-12-30
CA2968180A1 (fr) 2016-06-16
LTPA2022505I1 (fr) 2022-06-10

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