FR2285886A2 - 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. - Google Patents
2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc.Info
- Publication number
- FR2285886A2 FR2285886A2 FR7432772A FR7432772A FR2285886A2 FR 2285886 A2 FR2285886 A2 FR 2285886A2 FR 7432772 A FR7432772 A FR 7432772A FR 7432772 A FR7432772 A FR 7432772A FR 2285886 A2 FR2285886 A2 FR 2285886A2
- Authority
- FR
- France
- Prior art keywords
- active
- oxazines
- nervous system
- central nervous
- analgesics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Oxazines of formula (I) are new (where X1 = halogen, (esp. F or Cl), or CF3, in the m or p positions; R=H, methyl, isopropyl or propargyl) Active on the central nervous system, esp. as analgesics anti-aggressive agents, and agents active against morphine withdrawal symptoms. Some of the compounds (I) are anticonvulsants and nonanaleptics.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7432772A FR2285886A2 (en) | 1974-09-27 | 1974-09-27 | 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7432772A FR2285886A2 (en) | 1974-09-27 | 1974-09-27 | 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2285886A2 true FR2285886A2 (en) | 1976-04-23 |
FR2285886B2 FR2285886B2 (en) | 1979-03-30 |
Family
ID=9143538
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7432772A Granted FR2285886A2 (en) | 1974-09-27 | 1974-09-27 | 2-(3-or 4-substd.)phenyl-tetrahydro-1,4-oxazines - active on central nervous system as analgesics, anti-aggression agents etc. |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2285886A2 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2553411A1 (en) * | 1983-10-14 | 1985-04-19 | Lafon Labor | 2-Halogenophenylmorpholine derivatives, process for preparing them and their therapeutic use |
EP0435387A1 (en) * | 1989-12-29 | 1991-07-03 | Shell Internationale Researchmaatschappij B.V. | Piperidine derivatives |
EP2221305A1 (en) | 2005-07-22 | 2010-08-25 | Mitsubishi Tanabe Pharma Corporation | Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent |
US8906908B2 (en) | 2010-05-21 | 2014-12-09 | Research Triangle Institute | Hydroxybupropion analogues for treating drug dependence |
US9617229B2 (en) | 2010-05-21 | 2017-04-11 | Research Triangle Institute | Phenylmorpholines and analogues thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1564792A (en) * | 1968-03-04 | 1969-04-25 |
-
1974
- 1974-09-27 FR FR7432772A patent/FR2285886A2/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1564792A (en) * | 1968-03-04 | 1969-04-25 |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2553411A1 (en) * | 1983-10-14 | 1985-04-19 | Lafon Labor | 2-Halogenophenylmorpholine derivatives, process for preparing them and their therapeutic use |
EP0435387A1 (en) * | 1989-12-29 | 1991-07-03 | Shell Internationale Researchmaatschappij B.V. | Piperidine derivatives |
EP2221305A1 (en) | 2005-07-22 | 2010-08-25 | Mitsubishi Tanabe Pharma Corporation | Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent |
EP2221304A1 (en) | 2005-07-22 | 2010-08-25 | Mitsubishi Tanabe Pharma Corporation | Method for synthesizing intermediate compound for synthesizing a pharmaceutical agent |
US7994315B2 (en) | 2005-07-22 | 2011-08-09 | Mitsubishi Tanabe Pharma Corporation | Intermediate compound for synthesizing pharmaceutical agent and production method thereof |
US8906908B2 (en) | 2010-05-21 | 2014-12-09 | Research Triangle Institute | Hydroxybupropion analogues for treating drug dependence |
US9527823B2 (en) | 2010-05-21 | 2016-12-27 | Research Triangle Institute | Hydroxybupropion analogues for treating drug dependence |
US9617229B2 (en) | 2010-05-21 | 2017-04-11 | Research Triangle Institute | Phenylmorpholines and analogues thereof |
Also Published As
Publication number | Publication date |
---|---|
FR2285886B2 (en) | 1979-03-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CD | Change of name or company name |