FR2260332A1 - 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity - Google Patents

1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity

Info

Publication number
FR2260332A1
FR2260332A1 FR7404625A FR7404625A FR2260332A1 FR 2260332 A1 FR2260332 A1 FR 2260332A1 FR 7404625 A FR7404625 A FR 7404625A FR 7404625 A FR7404625 A FR 7404625A FR 2260332 A1 FR2260332 A1 FR 2260332A1
Authority
FR
France
Prior art keywords
vasodilator
diuretic
phenyl
indoles
aminocarbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7404625A
Other languages
French (fr)
Other versions
FR2260332B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7404625A priority Critical patent/FR2260332A1/en
Publication of FR2260332A1 publication Critical patent/FR2260332A1/en
Application granted granted Critical
Publication of FR2260332B1 publication Critical patent/FR2260332B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)

Abstract

1-Phenyl-2-carbamylindoles of formula (I): (where Z is H or - conhr3; R3 is H or 1-4C alkyl; R' and R2 are 1-4C alkyl or, together with the attached N-atom are piperidino, pyrrolidino, morpholino, hexamethyleneimino, heptamethylleneimino), have respiratory analeptic, antiinflammatory, analgesic, vasodilator, diuretic, sedative and anti-ulcer activity.
FR7404625A 1974-02-12 1974-02-12 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity Granted FR2260332A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7404625A FR2260332A1 (en) 1974-02-12 1974-02-12 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7404625A FR2260332A1 (en) 1974-02-12 1974-02-12 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity

Publications (2)

Publication Number Publication Date
FR2260332A1 true FR2260332A1 (en) 1975-09-05
FR2260332B1 FR2260332B1 (en) 1978-01-13

Family

ID=9134786

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7404625A Granted FR2260332A1 (en) 1974-02-12 1974-02-12 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity

Country Status (1)

Country Link
FR (1) FR2260332A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071935A2 (en) * 1981-08-08 1983-02-16 Kali-Chemie Pharma GmbH 1-Phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them
WO2002006273A1 (en) * 2000-07-13 2002-01-24 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents
JP2005514365A (en) * 2001-11-22 2005-05-19 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Indole-2-carboxamide as an active factor 10 inhibitor

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0071935A2 (en) * 1981-08-08 1983-02-16 Kali-Chemie Pharma GmbH 1-Phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them
EP0071935A3 (en) * 1981-08-08 1983-08-17 Kali-Chemie Pharma Gmbh 1-phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them
US4803198A (en) * 1981-08-08 1989-02-07 Kali-Chemie Pharma Gmbh 1-Phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them
WO2002006273A1 (en) * 2000-07-13 2002-01-24 Boehringer Ingelheim Pharmaceuticals, Inc. Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents
JP2005514365A (en) * 2001-11-22 2005-05-19 アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Indole-2-carboxamide as an active factor 10 inhibitor
JP4664592B2 (en) * 2001-11-22 2011-04-06 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Indole-2-carboxamide as an active factor 10 inhibitor

Also Published As

Publication number Publication date
FR2260332B1 (en) 1978-01-13

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Legal Events

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