FR2260332A1 - 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity - Google Patents
1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activityInfo
- Publication number
- FR2260332A1 FR2260332A1 FR7404625A FR7404625A FR2260332A1 FR 2260332 A1 FR2260332 A1 FR 2260332A1 FR 7404625 A FR7404625 A FR 7404625A FR 7404625 A FR7404625 A FR 7404625A FR 2260332 A1 FR2260332 A1 FR 2260332A1
- Authority
- FR
- France
- Prior art keywords
- vasodilator
- diuretic
- phenyl
- indoles
- aminocarbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
Abstract
1-Phenyl-2-carbamylindoles of formula (I): (where Z is H or - conhr3; R3 is H or 1-4C alkyl; R' and R2 are 1-4C alkyl or, together with the attached N-atom are piperidino, pyrrolidino, morpholino, hexamethyleneimino, heptamethylleneimino), have respiratory analeptic, antiinflammatory, analgesic, vasodilator, diuretic, sedative and anti-ulcer activity.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7404625A FR2260332A1 (en) | 1974-02-12 | 1974-02-12 | 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7404625A FR2260332A1 (en) | 1974-02-12 | 1974-02-12 | 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2260332A1 true FR2260332A1 (en) | 1975-09-05 |
FR2260332B1 FR2260332B1 (en) | 1978-01-13 |
Family
ID=9134786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7404625A Granted FR2260332A1 (en) | 1974-02-12 | 1974-02-12 | 1-Phenyl-2-aminocarbonyl-indoles - with respiratory analeptic, antiinflammatory analgesic, vasodilator, diuretic and anti-ulcer activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2260332A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0071935A2 (en) * | 1981-08-08 | 1983-02-16 | Kali-Chemie Pharma GmbH | 1-Phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them |
WO2002006273A1 (en) * | 2000-07-13 | 2002-01-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents |
JP2005514365A (en) * | 2001-11-22 | 2005-05-19 | アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Indole-2-carboxamide as an active factor 10 inhibitor |
-
1974
- 1974-02-12 FR FR7404625A patent/FR2260332A1/en active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0071935A2 (en) * | 1981-08-08 | 1983-02-16 | Kali-Chemie Pharma GmbH | 1-Phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them |
EP0071935A3 (en) * | 1981-08-08 | 1983-08-17 | Kali-Chemie Pharma Gmbh | 1-phenyl-2-aminocarbonylindole compounds, process and intermediates for their preparation and medicines containing them |
US4803198A (en) * | 1981-08-08 | 1989-02-07 | Kali-Chemie Pharma Gmbh | 1-Phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them |
WO2002006273A1 (en) * | 2000-07-13 | 2002-01-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted 1-(4-aminophenyl)indoles and their use as anti-inflammatory agents |
JP2005514365A (en) * | 2001-11-22 | 2005-05-19 | アベンティス・ファーマ・ドイチユラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Indole-2-carboxamide as an active factor 10 inhibitor |
JP4664592B2 (en) * | 2001-11-22 | 2011-04-06 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Indole-2-carboxamide as an active factor 10 inhibitor |
Also Published As
Publication number | Publication date |
---|---|
FR2260332B1 (en) | 1978-01-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |