FR2247213A1 - 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity - Google Patents
3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activityInfo
- Publication number
- FR2247213A1 FR2247213A1 FR7336858A FR7336858A FR2247213A1 FR 2247213 A1 FR2247213 A1 FR 2247213A1 FR 7336858 A FR7336858 A FR 7336858A FR 7336858 A FR7336858 A FR 7336858A FR 2247213 A1 FR2247213 A1 FR 2247213A1
- Authority
- FR
- France
- Prior art keywords
- antihistaminic
- sedative
- diuretic
- analgesic
- aminocarbonylmethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
of formula (I) (where R1, R2 are 1-4C alkyl; or N R1 R2 may be morpholino, pyrrolidino, piperidino, hexamethyleneimino) have diuretic, antihistaminic, sedative, analgesic and antiulcer activity. (I) is prepd. by refluxing acetic anhydride and cpd. (II).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7336858A FR2247213A1 (en) | 1973-10-16 | 1973-10-16 | 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7336858A FR2247213A1 (en) | 1973-10-16 | 1973-10-16 | 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2247213A1 true FR2247213A1 (en) | 1975-05-09 |
FR2247213B1 FR2247213B1 (en) | 1977-03-11 |
Family
ID=9126450
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7336858A Granted FR2247213A1 (en) | 1973-10-16 | 1973-10-16 | 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2247213A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993013083A1 (en) * | 1991-12-31 | 1993-07-08 | Fujisawa Pharmaceutical Co., Ltd. | Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity |
-
1973
- 1973-10-16 FR FR7336858A patent/FR2247213A1/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993013083A1 (en) * | 1991-12-31 | 1993-07-08 | Fujisawa Pharmaceutical Co., Ltd. | Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity |
Also Published As
Publication number | Publication date |
---|---|
FR2247213B1 (en) | 1977-03-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |