FR2247213A1 - 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity - Google Patents

3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity

Info

Publication number
FR2247213A1
FR2247213A1 FR7336858A FR7336858A FR2247213A1 FR 2247213 A1 FR2247213 A1 FR 2247213A1 FR 7336858 A FR7336858 A FR 7336858A FR 7336858 A FR7336858 A FR 7336858A FR 2247213 A1 FR2247213 A1 FR 2247213A1
Authority
FR
France
Prior art keywords
antihistaminic
sedative
diuretic
analgesic
aminocarbonylmethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7336858A
Other languages
French (fr)
Other versions
FR2247213B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7336858A priority Critical patent/FR2247213A1/en
Publication of FR2247213A1 publication Critical patent/FR2247213A1/en
Application granted granted Critical
Publication of FR2247213B1 publication Critical patent/FR2247213B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

of formula (I) (where R1, R2 are 1-4C alkyl; or N R1 R2 may be morpholino, pyrrolidino, piperidino, hexamethyleneimino) have diuretic, antihistaminic, sedative, analgesic and antiulcer activity. (I) is prepd. by refluxing acetic anhydride and cpd. (II).
FR7336858A 1973-10-16 1973-10-16 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity Granted FR2247213A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7336858A FR2247213A1 (en) 1973-10-16 1973-10-16 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7336858A FR2247213A1 (en) 1973-10-16 1973-10-16 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity

Publications (2)

Publication Number Publication Date
FR2247213A1 true FR2247213A1 (en) 1975-05-09
FR2247213B1 FR2247213B1 (en) 1977-03-11

Family

ID=9126450

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7336858A Granted FR2247213A1 (en) 1973-10-16 1973-10-16 3-Aminocarbonylmethyl-5-methyl-1,2,4-oxadiazoles - with diuretic, sedative, antihistaminic analgesic and antiulcer activity

Country Status (1)

Country Link
FR (1) FR2247213A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993013083A1 (en) * 1991-12-31 1993-07-08 Fujisawa Pharmaceutical Co., Ltd. Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993013083A1 (en) * 1991-12-31 1993-07-08 Fujisawa Pharmaceutical Co., Ltd. Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity

Also Published As

Publication number Publication date
FR2247213B1 (en) 1977-03-11

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Legal Events

Date Code Title Description
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