FR2193580A1 - Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines - Google Patents

Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines

Info

Publication number
FR2193580A1
FR2193580A1 FR7226880A FR7226880A FR2193580A1 FR 2193580 A1 FR2193580 A1 FR 2193580A1 FR 7226880 A FR7226880 A FR 7226880A FR 7226880 A FR7226880 A FR 7226880A FR 2193580 A1 FR2193580 A1 FR 2193580A1
Authority
FR
France
Prior art keywords
carboxylic acids
trifluoro methoxy
prepd
analgesics
anilines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7226880A
Other languages
French (fr)
Other versions
FR2193580B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7226880A priority Critical patent/FR2193580A1/en
Publication of FR2193580A1 publication Critical patent/FR2193580A1/en
Application granted granted Critical
Publication of FR2193580B1 publication Critical patent/FR2193580B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Abstract

Title cpds. are of formula (I): (where A = CH = or N; R = H or alkyl 1-6C, opt. substd. by the following halogens, (1-5C), hydroxyalkyl, NO2, NH2, (1-5C) mono-and dialkylamino or heterocycle 3-7 ring members 1-3 heteroatoms, the alkyl gps. being opt. branched.).
FR7226880A 1972-07-26 1972-07-26 Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines Granted FR2193580A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7226880A FR2193580A1 (en) 1972-07-26 1972-07-26 Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7226880A FR2193580A1 (en) 1972-07-26 1972-07-26 Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines

Publications (2)

Publication Number Publication Date
FR2193580A1 true FR2193580A1 (en) 1974-02-22
FR2193580B1 FR2193580B1 (en) 1975-08-08

Family

ID=9102381

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7226880A Granted FR2193580A1 (en) 1972-07-26 1972-07-26 Trifluoro methoxy anilino aryl carboxylic acids - analgesics, prepd. from ortho halo benzoic or pyridine carboxylic acids and trifluoro methoxy anilines

Country Status (1)

Country Link
FR (1) FR2193580A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2928546A1 (en) * 1979-07-14 1981-01-29 Bago Sa Labor Analgesic and antiinflammatory 2-anilino-nicotinic acid ester prodn. - by esterification of 2-halo-nicotinic acid with halomethyl pivalate or 3-halo-phthalide and reaction with substd. aniline
FR2462427A1 (en) * 1979-07-27 1981-02-13 Bago Sa Labor Analgesic and antiinflammatory 2-anilino-nicotinic acid ester prodn. - by esterification of 2-halo-nicotinic acid with halomethyl pivalate or 3-halo-phthalide and reaction with substd. aniline
US4255581A (en) * 1979-08-13 1981-03-10 Laboratories Bago, S.A. Process for the preparation of alkyl and aryl esters of 3'-substituted and 2', 3'-disubstituted 2-anilino-3-pyridinecarboxylic acids
FR2537579A1 (en) * 1982-12-10 1984-06-15 Bago Sa Labor Process for the preparation of alkyl and aryl esters of 3'-substituted and 2',3'-disubstituted 2-anilino-3-pyridinecarboxylic acids
EP0349902A2 (en) * 1988-07-08 1990-01-10 CHIESI FARMACEUTICI S.p.A. Processes for the preparation of morniflumate and analogous compounds

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2928546A1 (en) * 1979-07-14 1981-01-29 Bago Sa Labor Analgesic and antiinflammatory 2-anilino-nicotinic acid ester prodn. - by esterification of 2-halo-nicotinic acid with halomethyl pivalate or 3-halo-phthalide and reaction with substd. aniline
FR2462427A1 (en) * 1979-07-27 1981-02-13 Bago Sa Labor Analgesic and antiinflammatory 2-anilino-nicotinic acid ester prodn. - by esterification of 2-halo-nicotinic acid with halomethyl pivalate or 3-halo-phthalide and reaction with substd. aniline
US4255581A (en) * 1979-08-13 1981-03-10 Laboratories Bago, S.A. Process for the preparation of alkyl and aryl esters of 3'-substituted and 2', 3'-disubstituted 2-anilino-3-pyridinecarboxylic acids
FR2537579A1 (en) * 1982-12-10 1984-06-15 Bago Sa Labor Process for the preparation of alkyl and aryl esters of 3'-substituted and 2',3'-disubstituted 2-anilino-3-pyridinecarboxylic acids
EP0349902A2 (en) * 1988-07-08 1990-01-10 CHIESI FARMACEUTICI S.p.A. Processes for the preparation of morniflumate and analogous compounds
EP0349902A3 (en) * 1988-07-08 1991-04-10 CHIESI FARMACEUTICI S.p.A. Processes for the preparation of morniflumate and analogous compounds

Also Published As

Publication number Publication date
FR2193580B1 (en) 1975-08-08

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Legal Events

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