FR2160407B1 - - Google Patents
Info
- Publication number
- FR2160407B1 FR2160407B1 FR7239498A FR7239498A FR2160407B1 FR 2160407 B1 FR2160407 B1 FR 2160407B1 FR 7239498 A FR7239498 A FR 7239498A FR 7239498 A FR7239498 A FR 7239498A FR 2160407 B1 FR2160407 B1 FR 2160407B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5375071A GB1400999A (en) | 1971-11-19 | 1971-11-19 | Imidazo-triazine compounds and their use in therapeutic compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2160407A1 FR2160407A1 (fr) | 1973-06-29 |
FR2160407B1 true FR2160407B1 (fr) | 1975-10-17 |
Family
ID=10468856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7239498A Expired FR2160407B1 (fr) | 1971-11-19 | 1972-11-08 |
Country Status (18)
Country | Link |
---|---|
US (1) | US3840537A (fr) |
JP (1) | JPS563873B2 (fr) |
AT (1) | AT321923B (fr) |
AU (1) | AU472127B2 (fr) |
BE (1) | BE791025A (fr) |
CA (1) | CA990292A (fr) |
CH (1) | CH594671A5 (fr) |
DE (1) | DE2255172A1 (fr) |
DK (1) | DK138691B (fr) |
ES (1) | ES408736A1 (fr) |
FR (1) | FR2160407B1 (fr) |
GB (1) | GB1400999A (fr) |
IE (1) | IE37046B1 (fr) |
IL (1) | IL40686A (fr) |
NL (1) | NL7215646A (fr) |
PH (1) | PH9669A (fr) |
SE (1) | SE402915B (fr) |
ZA (1) | ZA727532B (fr) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1457873A (en) * | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
DE2314488C3 (de) * | 1973-03-23 | 1979-01-04 | C.H. Boehringer Sohn, 6507 Ingelheim | 8-(2,6-Dichlorphenyl)-7-(4-chlorphenyl)-5-oxo-233,8-tetrahydro-imidazo [1,2-a] -s-triazin, Verfahren zu dessen Herstellung und dieses enthaltene Arzneimittel |
DE2335193A1 (de) * | 1973-07-11 | 1975-01-30 | Hoechst Ag | Bis-triazinobenzimidazole und ihre herstellung |
US4115572A (en) * | 1977-02-03 | 1978-09-19 | American Cyanamid Company | Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma |
USRE30511E (en) * | 1977-02-03 | 1981-02-10 | American Cyanamid Company | Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones |
US4107307A (en) * | 1977-02-03 | 1978-08-15 | American Cyanamid Company | Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones |
DK109578A (da) * | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af heterocycliske forbindelser |
US4107308A (en) * | 1977-10-18 | 1978-08-15 | American Cyanamid Company | Imidazo[1,5-d]-as-triazines |
US4308384A (en) * | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
HU187474B (en) * | 1981-11-18 | 1986-01-28 | Gyogyszerkutato Intezet,Hu | Process for producing new spiro-pyrazole-square bracket-1,5-d-square bracket closed-square bracket-1,2,4-square bracket closed-triazine derivatives |
US4395547A (en) * | 1982-02-10 | 1983-07-26 | American Cyanamid Co. | Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones |
AU622330B2 (en) * | 1989-06-23 | 1992-04-02 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides |
US6624181B1 (en) * | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
DE59803108D1 (de) * | 1997-11-12 | 2002-03-21 | Bayer Ag | 2-phenyl-substituierte imidazotriazinone als phosphodiesterase inhibitoren |
DE19827640A1 (de) * | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
PL346271A1 (en) | 1998-08-26 | 2002-01-28 | Smithkline Beecham Corp | Therapies for treating pulmonary diseases |
JP5038568B2 (ja) * | 1999-08-21 | 2012-10-03 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 協力剤の組合せ物 |
MXPA03010119A (es) * | 2001-05-09 | 2005-03-07 | Bayer Healthcare Ag | Nuevo uso de imidazotriazinonas 2-fenilo sustituidas. |
GB0113344D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel heterocycles 3 |
GB0113343D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel Heterocycles 2 |
DE10135815A1 (de) | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
DE10232113A1 (de) * | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
DE602004021363D1 (de) * | 2003-04-01 | 2009-07-16 | Smithkline Beecham Corp | Imidazotriazin verbindungen zur behandlung von krebserkrankungen |
EP2168968B1 (fr) | 2004-04-02 | 2017-08-23 | OSI Pharmaceuticals, LLC | Inhibiteurs hétérobicycliques de la protéine kinase à anneau bicyclique substitué en 6,6 |
DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
CA2623657A1 (fr) * | 2005-09-29 | 2007-04-12 | Bayer Healthcare Ag | Inhibiteurs pde et combinaisons de ceux-ci pour traiter des troubles urinaires |
KR20080078668A (ko) * | 2005-11-17 | 2008-08-27 | 오에스아이 파마슈티컬스, 인코포레이티드 | 융합된 바이사이클릭 mTOR 억제자 |
CN101711153A (zh) * | 2007-06-13 | 2010-05-19 | 拜耳先灵制药股份公司 | 用于治疗听觉损伤的pde抑制剂 |
CA2752826A1 (fr) | 2009-04-20 | 2010-10-28 | OSI Pharmaceuticals, LLC | Preparation de c-pyrazine-methylamines |
CN103374002B (zh) * | 2012-04-19 | 2015-07-15 | 山东轩竹医药科技有限公司 | 磷酸二酯酶-5抑制剂 |
US20180044343A1 (en) * | 2015-03-16 | 2018-02-15 | Sumitomo Dainippon Pharma Co., Ltd. | Bicyclic imidazolo derivative |
WO2017000276A1 (fr) * | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Composés hétérocycliques bicycliques utilisés en tant qu'inhibiteurs de pde2 |
WO2017204316A1 (fr) * | 2016-05-27 | 2017-11-30 | 塩野義製薬株式会社 | Dérivé de 5-oxo-1,2,4-triazine et composition pharmaceutique correspondante |
-
0
- BE BE791025D patent/BE791025A/fr unknown
-
1971
- 1971-11-19 GB GB5375071A patent/GB1400999A/en not_active Expired
-
1972
- 1972-10-23 ZA ZA727532A patent/ZA727532B/xx unknown
- 1972-10-23 DK DK525172AA patent/DK138691B/da unknown
- 1972-10-23 IE IE1433/72A patent/IE37046B1/xx unknown
- 1972-10-25 US US00300749A patent/US3840537A/en not_active Expired - Lifetime
- 1972-10-26 AU AU48191/72A patent/AU472127B2/en not_active Expired
- 1972-10-27 IL IL40686A patent/IL40686A/xx unknown
- 1972-11-01 CA CA155,720A patent/CA990292A/en not_active Expired
- 1972-11-06 SE SE7214358A patent/SE402915B/xx unknown
- 1972-11-08 FR FR7239498A patent/FR2160407B1/fr not_active Expired
- 1972-11-10 DE DE2255172A patent/DE2255172A1/de not_active Withdrawn
- 1972-11-16 PH PH14090*UA patent/PH9669A/en unknown
- 1972-11-16 CH CH1668372A patent/CH594671A5/xx not_active IP Right Cessation
- 1972-11-17 AT AT982372A patent/AT321923B/de not_active IP Right Cessation
- 1972-11-17 ES ES408736A patent/ES408736A1/es not_active Expired
- 1972-11-17 NL NL7215646A patent/NL7215646A/xx not_active Application Discontinuation
- 1972-11-17 JP JP11549572A patent/JPS563873B2/ja not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2255172A1 (de) | 1973-05-24 |
IE37046L (en) | 1973-05-19 |
IL40686A0 (en) | 1972-12-29 |
PH9669A (en) | 1976-02-10 |
DK138691C (fr) | 1979-03-26 |
DK138691B (da) | 1978-10-16 |
JPS563873B2 (fr) | 1981-01-27 |
CA990292A (en) | 1976-06-01 |
SE402915B (sv) | 1978-07-24 |
IE37046B1 (en) | 1977-04-27 |
NL7215646A (fr) | 1973-05-22 |
US3840537A (en) | 1974-10-08 |
FR2160407A1 (fr) | 1973-06-29 |
ES408736A1 (es) | 1976-03-01 |
GB1400999A (en) | 1975-07-16 |
AU4819172A (en) | 1974-05-16 |
IL40686A (en) | 1975-12-31 |
ZA727532B (en) | 1973-07-25 |
AU472127B2 (en) | 1976-05-20 |
BE791025A (fr) | 1973-05-07 |
JPS4857993A (fr) | 1973-08-14 |
CH594671A5 (fr) | 1978-01-13 |
AT321923B (de) | 1975-04-25 |
Similar Documents
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |