FR2086133A2 - N-bis (3-thienylpropyl) phenethylamines -with coronary vasodilator - activity - Google Patents
N-bis (3-thienylpropyl) phenethylamines -with coronary vasodilator - activityInfo
- Publication number
- FR2086133A2 FR2086133A2 FR7103246A FR7103246A FR2086133A2 FR 2086133 A2 FR2086133 A2 FR 2086133A2 FR 7103246 A FR7103246 A FR 7103246A FR 7103246 A FR7103246 A FR 7103246A FR 2086133 A2 FR2086133 A2 FR 2086133A2
- Authority
- FR
- France
- Prior art keywords
- alkyl
- thienylpropyl
- phenethylamines
- bis
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cpds. are of formula: their isomers and acid-addn. salts (X = thienyl opt. substd. with one or more alkyls; A . B = C(OH)CH2 or C=CH- in which one of the H atoms of B or the CH2 gp. between B and -NR1 may be replaced by alkyl; R1 = H, alkyl; R2 = H, alkyl; R3 = H, OH; R4, R5 = H, OH, halogen, alkyl, haloalkyl, alkoxy). The alkyl substition of the B and CH2 gps. are an addn. to the parent patent.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2965670A | 1970-04-17 | 1970-04-17 | |
IT5307270A IT1051557B (en) | 1970-08-27 | 1970-08-27 | 1,1-dithienyl (3)-propane derivs - for treatment of heart and circula diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2086133A2 true FR2086133A2 (en) | 1971-12-31 |
FR2086133B2 FR2086133B2 (en) | 1974-08-30 |
Family
ID=26329528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7103246A Granted FR2086133A2 (en) | 1970-04-17 | 1971-02-01 | N-bis (3-thienylpropyl) phenethylamines -with coronary vasodilator - activity |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2086133A2 (en) |
SE (1) | SE394280B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2377396A1 (en) * | 1977-01-12 | 1978-08-11 | Degussa | DITHIENYLALKYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC USES |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7004410A (en) * | 1969-04-26 | 1970-10-28 |
-
1970
- 1970-10-26 SE SE7014443A patent/SE394280B/en unknown
-
1971
- 1971-02-01 FR FR7103246A patent/FR2086133A2/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7004410A (en) * | 1969-04-26 | 1970-10-28 |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2377396A1 (en) * | 1977-01-12 | 1978-08-11 | Degussa | DITHIENYLALKYLAMINES, THEIR PREPARATION AND THEIR THERAPEUTIC USES |
Also Published As
Publication number | Publication date |
---|---|
FR2086133B2 (en) | 1974-08-30 |
SE394280B (en) | 1977-06-20 |
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