FR2068539A1 - 2-(6-Methoxy-2-naphthyl) propionic acid prepns. - anti-pyretics, analgesics, anti-inflammatory agents - Google Patents

2-(6-Methoxy-2-naphthyl) propionic acid prepns. - anti-pyretics, analgesics, anti-inflammatory agents

Info

Publication number
FR2068539A1
FR2068539A1 FR7009733A FR7009733A FR2068539A1 FR 2068539 A1 FR2068539 A1 FR 2068539A1 FR 7009733 A FR7009733 A FR 7009733A FR 7009733 A FR7009733 A FR 7009733A FR 2068539 A1 FR2068539 A1 FR 2068539A1
Authority
FR
France
Prior art keywords
analgesics
naphthyl
methoxy
propionic acid
prepns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7009733A
Other languages
French (fr)
Other versions
FR2068539B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of FR2068539A1 publication Critical patent/FR2068539A1/en
Application granted granted Critical
Publication of FR2068539B1 publication Critical patent/FR2068539B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/027—Organoboranes and organoborohydrides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/02—Magnesium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/06—Zinc compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

2-(6-methoxy-2-naphthyl)propionic acid (I) is prepd. by 34 claimed methods from derivs. of (I) which include (cyclo)alk-2-enyl-, 1-aralkyl-, alkyl-, alkenyl-beta-haloalkyl-, aldoxime-, amide-, substd. acid- and alcohol-,. One such method is to hydrolyse the ester in a 0.1-5% vol. soln. of acid in a suitable stable solvent at a temp. of 10 degrees C to b.pt. of soln. Cpds. are anti-inflammatories, analgesics, antipyretics and pain killers.
FR7009733A 1969-09-30 1970-03-18 2-(6-Methoxy-2-naphthyl) propionic acid prepns. - anti-pyretics, analgesics, anti-inflammatory agents Granted FR2068539A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US86249869A 1969-09-30 1969-09-30
US86245369A 1969-09-30 1969-09-30
US86247169A 1969-09-30 1969-09-30
US86245569A 1969-09-30 1969-09-30
US86247569A 1969-09-30 1969-09-30
US86245469A 1969-09-30 1969-09-30
US86250169A 1969-09-30 1969-09-30

Publications (2)

Publication Number Publication Date
FR2068539A1 true FR2068539A1 (en) 1971-08-27
FR2068539B1 FR2068539B1 (en) 1974-02-22

Family

ID=27569931

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7009733A Granted FR2068539A1 (en) 1969-09-30 1970-03-18 2-(6-Methoxy-2-naphthyl) propionic acid prepns. - anti-pyretics, analgesics, anti-inflammatory agents

Country Status (7)

Country Link
JP (1) JPS516667B1 (en)
BR (1) BR6915472D0 (en)
CH (6) CH543467A (en)
DK (1) DK145338C (en)
FI (1) FI50620C (en)
FR (1) FR2068539A1 (en)
NO (1) NO128604B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54128261U (en) * 1978-02-28 1979-09-06
JP2023112428A (en) * 2022-02-01 2023-08-14 株式会社東芝 Magnetic head and magnetic recording/reproducing device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6910156A (en) * 1968-07-02 1970-01-06

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6910156A (en) * 1968-07-02 1970-01-06

Also Published As

Publication number Publication date
FI50620C (en) 1976-05-10
FI50620B (en) 1976-02-02
CH547247A (en) 1974-03-29
DK145338B (en) 1982-11-01
BR6915472D0 (en) 1973-06-14
CH549544A (en) 1974-05-31
NO128604B (en) 1973-12-17
FR2068539B1 (en) 1974-02-22
CH547246A (en) 1974-03-29
CH549545A (en) 1974-05-31
CH547248A (en) 1974-03-29
DK145338C (en) 1983-03-21
CH543467A (en) 1973-10-31
JPS516667B1 (en) 1976-03-01

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