FR2042333A1 - - Google Patents
Info
- Publication number
- FR2042333A1 FR2042333A1 FR7013609A FR7013609A FR2042333A1 FR 2042333 A1 FR2042333 A1 FR 2042333A1 FR 7013609 A FR7013609 A FR 7013609A FR 7013609 A FR7013609 A FR 7013609A FR 2042333 A1 FR2042333 A1 FR 2042333A1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2990769A JPS5010299B1 (fr) | 1969-04-16 | 1969-04-16 | |
JP2990569A JPS5010298B1 (fr) | 1969-04-16 | 1969-04-16 | |
JP3416669 | 1969-05-02 | ||
JP3416769 | 1969-05-02 | ||
JP8004269A JPS5010308B1 (fr) | 1969-10-03 | 1969-10-03 | |
JP8004169 | 1969-10-03 | ||
JP10280969 | 1969-12-19 | ||
JP10419469A JPS4939995B1 (fr) | 1969-12-23 | 1969-12-23 | |
US2641270A | 1970-04-07 | 1970-04-07 | |
US00206966A US3821404A (en) | 1969-04-16 | 1971-12-10 | Phenoxy carboxylic acid derivatives as anti-atherosclerosis agents |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2042333A1 true FR2042333A1 (fr) | 1971-02-12 |
FR2042333B1 FR2042333B1 (fr) | 1973-04-06 |
Family
ID=27579824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR707013609A Expired FR2042333B1 (fr) | 1969-04-16 | 1970-04-15 |
Country Status (9)
Country | Link |
---|---|
US (2) | US3716583A (fr) |
AT (2) | AT303015B (fr) |
BE (1) | BE748970A (fr) |
CA (1) | CA964273A (fr) |
CH (2) | CH539012A (fr) |
DK (1) | DK128731B (fr) |
FI (1) | FI52570C (fr) |
FR (1) | FR2042333B1 (fr) |
NL (1) | NL139016B (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2193592A1 (fr) * | 1972-07-20 | 1974-02-22 | Sumitomo Chemical Co | |
FR2235680A1 (fr) * | 1973-07-02 | 1975-01-31 | Sumitomo Chemical Co |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4008265A (en) * | 1971-05-22 | 1977-02-15 | Sumitomo Chemical Company, Limited | Novel bisphenoxy carboxylic acid derivatives and their salts |
US4092324A (en) * | 1971-05-22 | 1978-05-30 | Sumitomo Chemical Company, Limited | Diheterocyclic esters of 4-(1,1-bis-(phenoxy-propionic or -butoyric acid)-cyclohexane)α-methyl substituted |
JPS575214B2 (fr) * | 1972-06-01 | 1982-01-29 | ||
CH617417A5 (fr) * | 1973-12-27 | 1980-05-30 | Siegfried Ag | |
AT353776B (de) * | 1973-12-27 | 1979-12-10 | Siegfried Ag | Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen |
FR2428629A1 (fr) * | 1978-06-14 | 1980-01-11 | Hexachimie | Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique |
EP0363760A1 (fr) * | 1988-10-12 | 1990-04-18 | Bayer Ag | Ethers aromatiques |
US5179097A (en) * | 1991-06-10 | 1993-01-12 | Angres Isaac A | Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids |
US6083497A (en) | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
BR0206654A (pt) * | 2001-01-26 | 2004-02-25 | Schering Corp | Combinações de ativador(es) de receptor ativado por proliferação de peroxisoma (ppar) e inibidor(es) de absorção de esterol e tratamentos para indicações vasculares |
PL205343B1 (pl) * | 2001-01-26 | 2010-04-30 | Schering Corp | Zastosowanie inhibitora wchłaniania sterolu |
EP1541175A3 (fr) * | 2001-01-26 | 2006-04-12 | Schering Corporation | Combinaisons d'un inhibiteur de l'absorption de sterol avec un agent cardio-vasculaire pour le traitement des maladies cardio-vasculaires |
PT1353694E (pt) * | 2001-01-26 | 2008-03-12 | Schering Corp | Combinações de ezetimiba com aspirina para o tratamento de doenças vasculares |
EP1671650A1 (fr) * | 2001-01-26 | 2006-06-21 | Schering Corporation | Combinaisons d'un inhibiteur d'absorption de sterol avec un dérivé de l'acide nicotinique et traitement des maladies cardio-vasculaires |
US7071181B2 (en) * | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
US20060287254A1 (en) * | 2001-01-26 | 2006-12-21 | Schering Corporation | Use of substituted azetidinone compounds for the treatment of sitosterolemia |
DE60221798T2 (de) * | 2001-01-26 | 2008-06-05 | Schering Corp. | Kombinationen von gallensäure sequestriermitteln und hemmern der sterol absorption zur behandlung von kardiovaskulären indikationen |
EP1911462A3 (fr) | 2001-01-26 | 2011-11-30 | Schering Corporation | Combinaisons comprenant un inhibiteur d'absorption de stérol |
MXPA03010843A (es) * | 2001-05-25 | 2004-02-17 | Schering Corp | Uso de derivados con azetidinona en el tratamiento de enfermedad de alzheimer. |
BR0212907A (pt) * | 2001-09-21 | 2004-10-13 | Schering Corp | Métodos para tratamento ou prevenção de inflamação vascular usando inibidor(es) da absorção de esteróis |
ES2272776T3 (es) * | 2001-09-21 | 2007-05-01 | Schering Corporation | Tratamiento de xantomas con derivados de azetidinona como inhibidores de la absorcion de esterol. |
US7053080B2 (en) * | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
US20030119808A1 (en) * | 2001-09-21 | 2003-06-26 | Schering Corporation | Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects |
US7056906B2 (en) * | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
WO2004043456A1 (fr) * | 2002-11-06 | 2004-05-27 | Schering Corporation | Inhibiteurs d'absorption du cholesterol pour le traitement de la demyelination |
CA2517573C (fr) * | 2003-03-07 | 2011-12-06 | Schering Corporation | Composes d'azetidinone substitues, formulations et utilisations de ceux-ci pour traiter l'hypercholesterolemie |
CN1756756A (zh) * | 2003-03-07 | 2006-04-05 | 先灵公司 | 取代的2-吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途 |
ES2311806T3 (es) | 2003-03-07 | 2009-02-16 | Schering Corporation | Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
US7459442B2 (en) * | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
KR20060021870A (ko) * | 2003-05-30 | 2006-03-08 | 랜박시 래보러터리스 리미티드 | 치환된 피롤 유도체와 hmg―co 억제제로서의 이의용도 |
WO2005046797A2 (fr) * | 2003-11-05 | 2005-05-26 | Schering Corporation | Combinaisons de modulateurs lipidiques et d'azetidinones substituees et traitements d'affections vasculaires |
US6998397B2 (en) * | 2004-07-23 | 2006-02-14 | Drebsk Comptech, Inc. | Method for decreasing cholesterol level in blood |
WO2007054896A1 (fr) * | 2005-11-08 | 2007-05-18 | Ranbaxy Laboratories Limited | Procede de preparation de sel hemicalcique d’acide (3r,5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethylphenylamino)carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoique |
US20070238716A1 (en) * | 2006-03-14 | 2007-10-11 | Murthy Ayanampudi S R | Statin stabilizing dosage formulations |
WO2008010087A2 (fr) * | 2006-07-14 | 2008-01-24 | Ranbaxy Laboratories Limited | FORMES POLYMORPHES D'UN INHIBITEUR DE LA HMG-CoA-RÉDUCTASE ET LEURS UTILISATIONS |
TW200901959A (en) | 2007-03-09 | 2009-01-16 | Indigene Pharmaceuticals Inc | Combination of metformin R-(+) lipoate and antihyperlipidemic agents for the treatment of diabetic hyperglycemia and diabetic complications |
WO2012027331A1 (fr) | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions et procédés pour traiter ou prévenir un syndrome métabolique et des maladies et troubles associés |
KR20170115071A (ko) | 2015-02-06 | 2017-10-16 | 인터셉트 파마슈티컬즈, 인크. | 병용 요법을 위한 약제학적 조성물 |
CN104610051A (zh) * | 2015-03-02 | 2015-05-13 | 北京万全德众医药生物技术有限公司 | 一种制备克利贝特杂质的方法 |
CN114144185A (zh) | 2019-05-30 | 2022-03-04 | 英特塞普特医药品公司 | 用于治疗胆汁淤积性肝病的包含fxr激动剂和贝特类的药物组合物 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB970969A (en) * | 1963-08-15 | 1964-09-23 | Shell Int Research | Dicarboxylic acids and their esters and a process for the preparation thereof |
FR1380816A (fr) * | 1963-11-18 | 1964-12-04 | Ciba Geigy | Procédé de préparation de nouveaux acides isobutyriques, entre autres de l'acide alpha-[p-(2-p'-chlorophényl-propyl-[2])-phénoxy]-isobutyrique |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2444594A (en) * | 1947-08-07 | 1948-07-06 | American Cyanamid Co | Isopropylidene-p-phenoxy-2-ethanol-p-phenoxyacetic acid |
US2541003A (en) * | 1948-08-17 | 1951-02-06 | American Cyanamid Co | Process for reacting salts of phenols with halo-alkanoic acid compounds |
GB860303A (en) * | 1958-06-20 | 1961-02-01 | Ici Ltd | Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª |
US3169144A (en) * | 1960-08-12 | 1965-02-09 | Massarani Elena | Anticholesterinemic and antilipaemic agents |
US3470234A (en) * | 1965-08-23 | 1969-09-30 | Ciba Geigy Corp | Diaryl substituted benzocycloalkanes |
US3470235A (en) * | 1965-11-05 | 1969-09-30 | Eastman Kodak Co | Alicyclic bisphenyleneoxydicarboxylic acids,salts and esters |
GB1121722A (en) * | 1966-03-31 | 1968-07-31 | Ici Ltd | New carboxylic acid derivatives |
US3630715A (en) * | 1968-12-19 | 1971-12-28 | Weston Chemical Corp | Alkylene bis (phenoxyacetic acid) derivatives as herbicides |
US3755603A (en) * | 1970-07-01 | 1973-08-28 | Syntex Corp | Biphenylyloxyacetic acids in pharmaceutical compositions |
-
1970
- 1970-04-07 FI FI700963A patent/FI52570C/fi active
- 1970-04-07 US US00026412A patent/US3716583A/en not_active Expired - Lifetime
- 1970-04-10 CA CA079,830A patent/CA964273A/en not_active Expired
- 1970-04-15 AT AT784271A patent/AT303015B/de not_active IP Right Cessation
- 1970-04-15 BE BE748970D patent/BE748970A/fr not_active IP Right Cessation
- 1970-04-15 DK DK189570AA patent/DK128731B/da unknown
- 1970-04-15 NL NL707005400A patent/NL139016B/xx not_active IP Right Cessation
- 1970-04-15 FR FR707013609A patent/FR2042333B1/fr not_active Expired
- 1970-04-15 AT AT344070A patent/AT302278B/de active
- 1970-04-16 CH CH567770A patent/CH539012A/de not_active IP Right Cessation
- 1970-04-16 CH CH748073A patent/CH556807A/xx not_active IP Right Cessation
-
1974
- 1974-04-10 US US05/459,861 patent/US3959484A/en not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB970969A (en) * | 1963-08-15 | 1964-09-23 | Shell Int Research | Dicarboxylic acids and their esters and a process for the preparation thereof |
FR1380816A (fr) * | 1963-11-18 | 1964-12-04 | Ciba Geigy | Procédé de préparation de nouveaux acides isobutyriques, entre autres de l'acide alpha-[p-(2-p'-chlorophényl-propyl-[2])-phénoxy]-isobutyrique |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2193592A1 (fr) * | 1972-07-20 | 1974-02-22 | Sumitomo Chemical Co | |
FR2235680A1 (fr) * | 1973-07-02 | 1975-01-31 | Sumitomo Chemical Co |
Also Published As
Publication number | Publication date |
---|---|
CA964273A (en) | 1975-03-11 |
NL139016B (nl) | 1973-06-15 |
FI52570C (fi) | 1977-10-10 |
FR2042333B1 (fr) | 1973-04-06 |
AT303015B (de) | 1972-11-10 |
US3959484A (en) | 1976-05-25 |
NL7005400A (fr) | 1970-10-20 |
FI52570B (fr) | 1977-06-30 |
CH539012A (de) | 1973-08-31 |
BE748970A (fr) | 1970-09-16 |
US3716583A (en) | 1973-02-13 |
CH556807A (de) | 1974-12-13 |
DK128731B (da) | 1974-06-24 |
AT302278B (de) | 1972-10-10 |