DK128731B - Analogifremgangsmåde til fremstilling af α-phenoxysubstituerede aliphatiske carboxylsyrederivater eller salte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af α-phenoxysubstituerede aliphatiske carboxylsyrederivater eller salte deraf.

Info

Publication number
DK128731B
DK128731B DK189570AA DK189570A DK128731B DK 128731 B DK128731 B DK 128731B DK 189570A A DK189570A A DK 189570AA DK 189570 A DK189570 A DK 189570A DK 128731 B DK128731 B DK 128731B
Authority
DK
Denmark
Prior art keywords
phenoxy
salts
preparation
carboxylic acid
acid derivatives
Prior art date
Application number
DK189570AA
Other languages
English (en)
Inventor
Y Nakamura
K Agatsuma
Y Tanaka
S Aono
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2990769A external-priority patent/JPS5010299B1/ja
Priority claimed from JP2990569A external-priority patent/JPS5010298B1/ja
Priority claimed from JP8004269A external-priority patent/JPS5010308B1/ja
Priority claimed from JP10419469A external-priority patent/JPS4939995B1/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Priority claimed from US00206966A external-priority patent/US3821404A/en
Publication of DK128731B publication Critical patent/DK128731B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK189570AA 1969-04-16 1970-04-15 Analogifremgangsmåde til fremstilling af α-phenoxysubstituerede aliphatiske carboxylsyrederivater eller salte deraf. DK128731B (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
JP2990769A JPS5010299B1 (da) 1969-04-16 1969-04-16
JP2990569A JPS5010298B1 (da) 1969-04-16 1969-04-16
JP3416769 1969-05-02
JP3416669 1969-05-02
JP8004169 1969-10-03
JP8004269A JPS5010308B1 (da) 1969-10-03 1969-10-03
JP10280969 1969-12-19
JP10419469A JPS4939995B1 (da) 1969-12-23 1969-12-23
US2641270A 1970-04-07 1970-04-07
US00206966A US3821404A (en) 1969-04-16 1971-12-10 Phenoxy carboxylic acid derivatives as anti-atherosclerosis agents

Publications (1)

Publication Number Publication Date
DK128731B true DK128731B (da) 1974-06-24

Family

ID=27579824

Family Applications (1)

Application Number Title Priority Date Filing Date
DK189570AA DK128731B (da) 1969-04-16 1970-04-15 Analogifremgangsmåde til fremstilling af α-phenoxysubstituerede aliphatiske carboxylsyrederivater eller salte deraf.

Country Status (9)

Country Link
US (2) US3716583A (da)
AT (2) AT303015B (da)
BE (1) BE748970A (da)
CA (1) CA964273A (da)
CH (2) CH556807A (da)
DK (1) DK128731B (da)
FI (1) FI52570C (da)
FR (1) FR2042333B1 (da)
NL (1) NL139016B (da)

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US4008265A (en) * 1971-05-22 1977-02-15 Sumitomo Chemical Company, Limited Novel bisphenoxy carboxylic acid derivatives and their salts
US4092324A (en) * 1971-05-22 1978-05-30 Sumitomo Chemical Company, Limited Diheterocyclic esters of 4-(1,1-bis-(phenoxy-propionic or -butoyric acid)-cyclohexane)α-methyl substituted
JPS575214B2 (da) * 1972-06-01 1982-01-29
JPS4931651A (da) * 1972-07-20 1974-03-22
JPS5735171B2 (da) * 1973-07-02 1982-07-27
CH617417A5 (da) * 1973-12-27 1980-05-30 Siegfried Ag
AT353776B (de) * 1973-12-27 1979-12-10 Siegfried Ag Verfahren zur herstellung von neuen alkan- saeuren, deren estern und salzen
FR2428629A1 (fr) * 1978-06-14 1980-01-11 Hexachimie Nouveaux composes bis(aryloxycarboxyliques), leur preparation et leur utilisation en therapeutique
EP0363760A1 (de) * 1988-10-12 1990-04-18 Bayer Ag Aromatische Ether
US5179097A (en) * 1991-06-10 1993-01-12 Angres Isaac A Salts of non-steroidal anti-inflammatory carboxylic acids and anti-lipidemic carboxylic acids
US6083497A (en) 1997-11-05 2000-07-04 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
EP1355644B1 (en) * 2001-01-26 2006-06-28 Schering Corporation The use of substituted azetidinone compounds for the treatment of sitosterolemia
US20020151536A1 (en) * 2001-01-26 2002-10-17 Schering Corporation Combinations of peroxisome proliferator-activated receptor (PPAR) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
EP1363668B1 (en) * 2001-01-26 2007-08-15 Schering Corporation Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
DK1353694T3 (da) * 2001-01-26 2008-03-25 Schering Corp Kombinationer af ezetimibe med aspirin til behandling af vaskulære tilstande
KR20040025889A (ko) * 2001-01-26 2004-03-26 쉐링 코포레이션 혈관성 질환을 치료하기 위한 스테롤 흡수 억제제와심혈관성 제제의 조합물
EP1911462A3 (en) 2001-01-26 2011-11-30 Schering Corporation Compositions comprising a sterol absorption inhibitor
WO2002058685A2 (en) * 2001-01-26 2002-08-01 Schering Corporation Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
AR038956A1 (es) * 2001-05-25 2005-02-02 Schering Corp Uso de un compuesto que regula la produccion o niveles de peptidos beta amiloides para la manufactura de un medicamento para tratar la enfermedad de alzheimer y/o para regular dichos niveles de peptidos amiloides beta en un sujeto
SI1427409T1 (sl) * 2001-09-21 2009-02-28 Schering Corp Postopki za zdravljenje ali preprečevanje vaskularnega vnetja z uporabo zaviralca(-ev) absorpcije sterola
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
DK1429756T3 (da) * 2001-09-21 2007-03-19 Schering Corp Behandling af xanthoma med azetidinonderivater som sterolabsorptionsinhibitorer
WO2004043457A1 (en) * 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
EP1601669B1 (en) * 2003-03-07 2008-12-24 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7192944B2 (en) * 2003-03-07 2007-03-20 Schering Corp. Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP5137228B2 (ja) 2003-03-07 2013-02-06 メルク・シャープ・アンド・ドーム・コーポレーション 高コレステロール血症の処置のための置換アゼチジノン化合物、置換アゼチジノン処方物およびそれらの使用
KR20110117731A (ko) * 2003-05-30 2011-10-27 랜박시 래보러터리스 리미티드 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도
CA2544309A1 (en) * 2003-11-05 2005-05-26 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
US6998397B2 (en) * 2004-07-23 2006-02-14 Drebsk Comptech, Inc. Method for decreasing cholesterol level in blood
SG166829A1 (en) * 2005-11-08 2010-12-29 Ranbaxy Lab Ltd Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
AU2007274724B2 (en) * 2006-07-14 2012-07-26 Ranbaxy Laboratories Limited Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof
AR065670A1 (es) 2007-03-09 2009-06-24 Indigene Pharmaceuticals Inc Combinacion de metformina r-(+) lipoato y agentes antihiperlipidemicos para el tratamiento de hiperglucemia diabetica y complicaciones diabeticas
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
BR112017016766B1 (pt) 2015-02-06 2023-11-07 Intercept Pharmaceuticals, Inc Composição compreendendo um agonista fxr e fibrato, bem como uso para tratar doença hepática colestática
CN104610051A (zh) * 2015-03-02 2015-05-13 北京万全德众医药生物技术有限公司 一种制备克利贝特杂质的方法
CN114144185A (zh) 2019-05-30 2022-03-04 英特塞普特医药品公司 用于治疗胆汁淤积性肝病的包含fxr激动剂和贝特类的药物组合物

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US2444594A (en) * 1947-08-07 1948-07-06 American Cyanamid Co Isopropylidene-p-phenoxy-2-ethanol-p-phenoxyacetic acid
US2541003A (en) * 1948-08-17 1951-02-06 American Cyanamid Co Process for reacting salts of phenols with halo-alkanoic acid compounds
GB860303A (en) * 1958-06-20 1961-02-01 Ici Ltd Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª
US3169144A (en) * 1960-08-12 1965-02-09 Massarani Elena Anticholesterinemic and antilipaemic agents
GB970969A (en) * 1963-08-15 1964-09-23 Shell Int Research Dicarboxylic acids and their esters and a process for the preparation thereof
FR1380816A (fr) * 1963-11-18 1964-12-04 Ciba Geigy Procédé de préparation de nouveaux acides isobutyriques, entre autres de l'acide alpha-[p-(2-p'-chlorophényl-propyl-[2])-phénoxy]-isobutyrique
US3470234A (en) * 1965-08-23 1969-09-30 Ciba Geigy Corp Diaryl substituted benzocycloalkanes
US3470235A (en) * 1965-11-05 1969-09-30 Eastman Kodak Co Alicyclic bisphenyleneoxydicarboxylic acids,salts and esters
GB1121722A (en) * 1966-03-31 1968-07-31 Ici Ltd New carboxylic acid derivatives
US3630715A (en) * 1968-12-19 1971-12-28 Weston Chemical Corp Alkylene bis (phenoxyacetic acid) derivatives as herbicides
US3755603A (en) * 1970-07-01 1973-08-28 Syntex Corp Biphenylyloxyacetic acids in pharmaceutical compositions

Also Published As

Publication number Publication date
FR2042333A1 (da) 1971-02-12
CH556807A (de) 1974-12-13
AT303015B (de) 1972-11-10
CA964273A (en) 1975-03-11
US3959484A (en) 1976-05-25
US3716583A (en) 1973-02-13
AT302278B (de) 1972-10-10
CH539012A (de) 1973-08-31
BE748970A (fr) 1970-09-16
NL7005400A (da) 1970-10-20
FI52570B (da) 1977-06-30
FI52570C (fi) 1977-10-10
FR2042333B1 (da) 1973-04-06
NL139016B (nl) 1973-06-15

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