FR2035795A1 - Anti-brucellosis vaccine prepn - Google Patents
Anti-brucellosis vaccine prepnInfo
- Publication number
- FR2035795A1 FR2035795A1 FR6909684A FR6909684A FR2035795A1 FR 2035795 A1 FR2035795 A1 FR 2035795A1 FR 6909684 A FR6909684 A FR 6909684A FR 6909684 A FR6909684 A FR 6909684A FR 2035795 A1 FR2035795 A1 FR 2035795A1
- Authority
- FR
- France
- Prior art keywords
- membranes
- pref
- vaccine
- papain
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/098—Brucella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Anti-brucellose vaccines based on membranes of bacteria Brucella abortus are prepd. by cultivating a weakened source of Brucella abortus Buch 19, disintegrating the bacteria by crushing, removing lipids from the membranes obtained, treating the membranes with papain and finally collecting the solid fraction and treating it to obtain the vaccine. After treatment with papain the membranes are pref. treated with soln of a surfactant such as a lauryl sulphate or chelate. Pref. the products obtained at each stage of the process are lyophilised. Pref. vaccine contains 500 mg of membrane extract in a suitable vehicle to form a does for immunising cattle.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR6909684A FR2035795A1 (en) | 1969-03-31 | 1969-03-31 | Anti-brucellosis vaccine prepn |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR6909684A FR2035795A1 (en) | 1969-03-31 | 1969-03-31 | Anti-brucellosis vaccine prepn |
Publications (1)
Publication Number | Publication Date |
---|---|
FR2035795A1 true FR2035795A1 (en) | 1970-12-24 |
Family
ID=9031640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR6909684A Withdrawn FR2035795A1 (en) | 1969-03-31 | 1969-03-31 | Anti-brucellosis vaccine prepn |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2035795A1 (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2287238A1 (en) * | 1974-10-11 | 1976-05-07 | Agronomique Inst Nat Rech | Anti brucellosis vaccine - consisting of the covering or walls of brucella cells free from their cytoplasmic contents |
US4148877A (en) * | 1975-12-29 | 1979-04-10 | Choay S. A. | Fraction capable of inducing in vivo a resistance to bacterial infections, process for obtaining said fraction from bacteria and drugs containing said fraction |
FR2506615A1 (en) * | 1981-06-01 | 1982-12-03 | Merieux Inst | Vaccine against brucellosis in humans - contg. phenol insoluble fraction of defatted Brucella abortus cells |
FR2524315A1 (en) * | 1982-04-02 | 1983-10-07 | Merieux Inst | Antigen for detecting cutaneous hypersensitivity to brucellosis - comprises the phenol-soluble fraction of delipidated Brucella abortus bacteria, esp. strain B19 |
CN113913389A (en) * | 2020-07-10 | 2022-01-11 | 内蒙古农业大学 | Hybridoma cell strain, monoclonal antibody of Brucella-resistant BAB antigen, and preparation and application thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE672177A (en) * | 1964-11-11 | 1966-05-10 |
-
1969
- 1969-03-31 FR FR6909684A patent/FR2035795A1/en not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE672177A (en) * | 1964-11-11 | 1966-05-10 |
Non-Patent Citations (2)
Title |
---|
*REVUE: "COMPTES RENDUS DE L'ACAD.DES SCIENCES" VOL:260 1965 PAGES 1514-1517 * |
REVUE: "NATURE", VOL : 207 1965 PAGES 1308-1309 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2287238A1 (en) * | 1974-10-11 | 1976-05-07 | Agronomique Inst Nat Rech | Anti brucellosis vaccine - consisting of the covering or walls of brucella cells free from their cytoplasmic contents |
US4148877A (en) * | 1975-12-29 | 1979-04-10 | Choay S. A. | Fraction capable of inducing in vivo a resistance to bacterial infections, process for obtaining said fraction from bacteria and drugs containing said fraction |
FR2506615A1 (en) * | 1981-06-01 | 1982-12-03 | Merieux Inst | Vaccine against brucellosis in humans - contg. phenol insoluble fraction of defatted Brucella abortus cells |
FR2524315A1 (en) * | 1982-04-02 | 1983-10-07 | Merieux Inst | Antigen for detecting cutaneous hypersensitivity to brucellosis - comprises the phenol-soluble fraction of delipidated Brucella abortus bacteria, esp. strain B19 |
CN113913389A (en) * | 2020-07-10 | 2022-01-11 | 内蒙古农业大学 | Hybridoma cell strain, monoclonal antibody of Brucella-resistant BAB antigen, and preparation and application thereof |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |