FR2034785A1 - Nucleoside-phosphonates,acides phosphoniques et sels d'acides phosphoniques correspondants ainsi que leurs intermediaires - Google Patents

Nucleoside-phosphonates,acides phosphoniques et sels d'acides phosphoniques correspondants ainsi que leurs intermediaires

Info

Publication number
FR2034785A1
FR2034785A1 FR7008406A FR7008406A FR2034785A1 FR 2034785 A1 FR2034785 A1 FR 2034785A1 FR 7008406 A FR7008406 A FR 7008406A FR 7008406 A FR7008406 A FR 7008406A FR 2034785 A1 FR2034785 A1 FR 2034785A1
Authority
FR
France
Prior art keywords
intermediaries
phosphonates
nucleoside
acid salts
phosphonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7008406A
Other languages
English (en)
Inventor
Henry Jones Gordon
Gilbert Moffatt John
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of FR2034785A1 publication Critical patent/FR2034785A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7008406A 1969-03-10 1970-03-09 Nucleoside-phosphonates,acides phosphoniques et sels d'acides phosphoniques correspondants ainsi que leurs intermediaires Withdrawn FR2034785A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80579269A 1969-03-10 1969-03-10

Publications (1)

Publication Number Publication Date
FR2034785A1 true FR2034785A1 (fr) 1970-12-18

Family

ID=25192524

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7008406A Withdrawn FR2034785A1 (fr) 1969-03-10 1970-03-09 Nucleoside-phosphonates,acides phosphoniques et sels d'acides phosphoniques correspondants ainsi que leurs intermediaires

Country Status (4)

Country Link
CA (1) CA931561A (fr)
DE (1) DE2009834A1 (fr)
FR (1) FR2034785A1 (fr)
GB (1) GB1301182A (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8420134A (nl) * 1983-05-24 1985-04-01 Stanford Res Inst Int Nieuwe antivirusmiddelen.
US5047533A (en) * 1983-05-24 1991-09-10 Sri International Acyclic purine phosphonate nucleotide analogs
NZ233197A (en) * 1989-04-13 1991-11-26 Richard Thomas Walker Aromatically substituted nucleotide derivatives, intermediates therefor and pharmaceutical compositions
US5585364A (en) * 1989-04-13 1996-12-17 British Technology Group Limited Antiviral compounds
EP0477454A1 (fr) * 1990-09-28 1992-04-01 Merrell Dow Pharmaceuticals Inc. Dérivés phosphonates de certains nucléosides
US5672697A (en) * 1991-02-08 1997-09-30 Gilead Sciences, Inc. Nucleoside 5'-methylene phosphonates
KR100386685B1 (ko) * 1993-09-17 2003-12-31 길리애드 사이언시즈, 인코포레이티드 뉴클레오타이드동족체류
US5798340A (en) * 1993-09-17 1998-08-25 Gilead Sciences, Inc. Nucleotide analogs
ATE486882T1 (de) * 1993-09-17 2010-11-15 Gilead Sciences Inc Nukleotidanaloge
US5852198A (en) * 1996-04-03 1998-12-22 Medichem Research, Inc. Wittig reagents and method for preparing α,β-unsaturated phosphonates
US5877166A (en) * 1996-04-29 1999-03-02 Sri International Enantiomerically pure 2-aminopurine phosphonate nucleotide analogs as antiviral agents
CN104926905B (zh) * 2014-03-20 2018-04-03 北京大学 三苯甲基类化合物及其制备方法和应用
CN113880883A (zh) * 2021-11-11 2022-01-04 奥锐特药业股份有限公司 核苷类磷酸酯前药的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238191A (en) * 1962-09-13 1966-03-01 Terrell C Myers Phosphonic acid analogs of nucleoside phosphates and method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3238191A (en) * 1962-09-13 1966-03-01 Terrell C Myers Phosphonic acid analogs of nucleoside phosphates and method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 90, no 19, 1968, pages 5337 - 5338 *

Also Published As

Publication number Publication date
DE2009834A1 (de) 1970-09-17
CA931561A (en) 1973-08-07
GB1301182A (en) 1972-12-29

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Legal Events

Date Code Title Description
RE Withdrawal of published application