FI963281A0 - Ureaasipohjainen rokote ja helicobakteeri-infektion hoito - Google Patents
Ureaasipohjainen rokote ja helicobakteeri-infektion hoitoInfo
- Publication number
- FI963281A0 FI963281A0 FI963281A FI963281A FI963281A0 FI 963281 A0 FI963281 A0 FI 963281A0 FI 963281 A FI963281 A FI 963281A FI 963281 A FI963281 A FI 963281A FI 963281 A0 FI963281 A0 FI 963281A0
- Authority
- FI
- Finland
- Prior art keywords
- urease
- treatment
- helicobacter pylori
- based vaccine
- pylori infection
- Prior art date
Links
- 206010019375 Helicobacter infections Diseases 0.000 title 1
- 108010046334 Urease Proteins 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/200,346 US6290962B1 (en) | 1992-11-03 | 1994-02-23 | Urease-based vaccine and treatment for helicobacter infection |
PCT/US1995/002202 WO1995022987A1 (en) | 1994-02-23 | 1995-02-23 | Urease-based vaccine and treatment for helicobacter infection |
Publications (2)
Publication Number | Publication Date |
---|---|
FI963281A0 true FI963281A0 (fi) | 1996-08-22 |
FI963281A FI963281A (fi) | 1996-10-22 |
Family
ID=22741337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI963281A FI963281A (fi) | 1994-02-23 | 1996-08-22 | Ureaasipohjainen rokote ja helicobakteeri-infektion hoito |
Country Status (15)
Country | Link |
---|---|
US (2) | US6290962B1 (fi) |
EP (1) | EP0751786A4 (fi) |
JP (1) | JPH09509661A (fi) |
AU (1) | AU694195C (fi) |
BR (1) | BR9506884A (fi) |
CA (1) | CA2184057A1 (fi) |
CZ (1) | CZ250396A3 (fi) |
FI (1) | FI963281A (fi) |
HU (1) | HUT75374A (fi) |
NO (1) | NO963508L (fi) |
NZ (1) | NZ282535A (fi) |
OA (1) | OA10372A (fi) |
PL (1) | PL179149B1 (fi) |
SK (1) | SK109496A3 (fi) |
WO (1) | WO1995022987A1 (fi) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6406703B1 (en) | 1993-07-27 | 2002-06-18 | Csl Limited | Treatment of H. pylori associated gastroduodenal disease |
NZ269124A (en) * | 1993-07-27 | 1997-06-24 | Csl Ltd | Vaccine comprising helicobacter antigens and its use in treating such infections |
CZ342697A3 (cs) * | 1995-04-28 | 1998-06-17 | Oravax, Inc. | Multimerní rekombinantní ureázová vakcina |
EP0862458A1 (en) * | 1995-10-09 | 1998-09-09 | Cortecs International Limited | Urease for the treatment of helicobacter pylori infections |
GB2307987A (en) * | 1995-12-06 | 1997-06-11 | Univ Manchester | Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto |
SE9600647D0 (sv) * | 1996-02-21 | 1996-02-21 | Bror Morein | Ny användning |
SI0885013T1 (fi) * | 1996-04-15 | 2001-12-31 | Anton Mayr | |
CA2252467A1 (en) * | 1996-04-23 | 1997-10-30 | Toray Industries, Inc. | Antipylori agent |
JP4112011B2 (ja) * | 1996-06-10 | 2008-07-02 | トーマス、ボレン | Helicobacter pyloriアドヘシン結合型抗原 |
US6248551B1 (en) * | 1997-03-28 | 2001-06-19 | Institut Pasteur | Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides |
US20020026035A1 (en) * | 1997-04-01 | 2002-02-28 | Harold Kleanthous | Helicobacter ghpo 1360 and ghpo 750 polypeptides and corresponding polynucleotide molecules |
JP3430853B2 (ja) | 1997-04-11 | 2003-07-28 | 株式会社ゲン・コーポレーション | 胃炎、胃潰瘍および十二指腸潰瘍の予防剤並びに治療剤 |
FR2762787B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter comprenant un adjuvant de type th1 |
JP2002505665A (ja) * | 1997-04-30 | 2002-02-19 | メリュー・オラバックス | Th1型アジュバントを含有する抗ヘリコバクターワクチン組成物 |
FR2762788B1 (fr) * | 1997-04-30 | 2000-10-06 | Pasteur Merieux Serums Vacc | Composition vaccinale anti-helicobacter pour usage par voie systemique sous-diaphragmatique |
US20030158396A1 (en) * | 1997-07-29 | 2003-08-21 | Harold Kleanthous | Identification of polynucleotides encoding novel helicobacter polypeptides in the helicobacter genome |
US6599509B2 (en) * | 1997-09-02 | 2003-07-29 | Massachusetts Institute Of Technology | Compositions and methods comprising helicobacter antigens for treatment and prevention of inflammatory bowel disease |
US5985631A (en) * | 1997-09-12 | 1999-11-16 | Oravax-Merieux Co. | Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease |
US20020151462A1 (en) * | 1998-02-19 | 2002-10-17 | Ling Lissolo | Helicobacter pylori membrane proteins |
GB9807721D0 (en) * | 1998-04-08 | 1998-06-10 | Chiron Spa | Antigen |
US6585975B1 (en) * | 1998-04-30 | 2003-07-01 | Acambis, Inc. | Use of Salmonella vectors for vaccination against helicobacter infection |
NZ509127A (en) | 1998-06-19 | 2004-01-30 | Merieux Oravax | Use of LT (E. coli) and CT (cholera toxin) for inducing immune responses against helicobacter infection |
US7384640B1 (en) * | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
US7041296B1 (en) * | 1999-11-12 | 2006-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of treating inflammatory bowel disease using cholera toxin B subunit |
GB9928196D0 (en) * | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
CA2351110A1 (en) * | 2000-07-17 | 2002-01-17 | Akzo Nobel N.V. | Helicobacter felis vaccine |
KR100898648B1 (ko) * | 2001-06-07 | 2009-05-22 | 와이어쓰 홀딩스 코포레이션 | 보조제로서 콜레라 홀로톡신의 돌연변이체 형태 |
EP1404279A4 (en) * | 2001-06-07 | 2007-08-08 | Wyeth Corp | MUTANT FORMS OF CHOLERA HOLOTOXIN AS ADJUVANT |
KR20050044523A (ko) * | 2001-11-19 | 2005-05-12 | 벡톤 디킨슨 앤드 컴퍼니 | 입자 형태의 약제학적 조성물 |
US7357949B2 (en) * | 2001-12-21 | 2008-04-15 | Agion Technologies Inc. | Encapsulated inorganic antimicrobial additive for controlled release |
US20030118658A1 (en) * | 2001-12-21 | 2003-06-26 | Trogolo Jeffrey A. | High aspect ratio encapsulated inorganic antimicrobial additive for controlled release |
FR2837835B1 (fr) * | 2002-03-29 | 2007-06-22 | Maria Urdaci | Souche bacillus subtilis cu1, son utilisation comme agent immunomodulateur du systeme immunitaire et vaccin recombinant vivant contre h. pylori la contenant |
CN1212126C (zh) * | 2002-07-09 | 2005-07-27 | 中国科学院长春应用化学研究所 | 纳米羟基磷灰石补钙剂 |
JP2004041084A (ja) * | 2002-07-11 | 2004-02-12 | Japan Science & Technology Corp | ヘリコバクター・ピロリ菌に対するワクチン用ペプチド、それをコードする遺伝子、その遺伝子が導入された形質転換体、及びそれらの利用方法 |
US7264800B2 (en) | 2002-07-18 | 2007-09-04 | Helix Biopharma Corporation | Method and composition for inhibiting cancer cell growth |
SI1530482T1 (sl) * | 2002-07-18 | 2014-03-31 | Helix Biopharma Corp. | Uporaba ureaze za inhibiranje rasti rakavih celic |
US20040109905A1 (en) * | 2002-09-18 | 2004-06-10 | Debasis Bagchi | Method and composition of anthocyanin-rich berry extracts that prevents or inhibits angiogenesis and helicobacter pylori and acts as a powerful antioxidant that provides various health benefits |
JP2008509127A (ja) * | 2004-08-04 | 2008-03-27 | ラボラトワ セローノ エス.エイ. | トランスフェクト細胞を含有するカプセル、それを調製する方法、並びに免疫及びワクチン接種するためのその使用 |
US8029777B2 (en) | 2004-08-13 | 2011-10-04 | Marshall Barry J | Helicobacter system and uses thereof |
CA2576280A1 (en) | 2004-08-13 | 2006-02-16 | Barry J. Marshall | Helicobacter pylori-based delivery system |
JP2010508828A (ja) * | 2006-11-10 | 2010-03-25 | マーシャル,バリー,ジェー. | 胃粘膜内へのペプチド送達方法及び装置 |
PL218700B1 (pl) | 2012-03-29 | 2015-01-30 | Gdański Univ Medyczny | Doustna szczepionka zawierająca przetrwalniki Bacillus subtilis oraz jej zastosowanie do immunizacji przeciwko Helicobacter pylori |
CN103461685B (zh) * | 2012-06-07 | 2014-10-22 | 中国农业科学院北京畜牧兽医研究所 | 瘤胃脲酶抗原组合物及其制备方法和应用及瘤胃脲酶抗原蛋白的应用 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5268278A (en) * | 1984-03-30 | 1993-12-07 | Istituto Farmacologico Serono S.P.A. | Genetic expression of somatostatin as hybrid polypeptide |
US4879213A (en) * | 1986-12-05 | 1989-11-07 | Scripps Clinic And Research Foundation | Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse |
US5268276A (en) * | 1988-09-16 | 1993-12-07 | Jan Holmgren | Recombinant systems for expression of cholera B-sub-unit with the aid of foreign promoters and/or leader peptides |
FR2637612B1 (fr) * | 1988-10-06 | 1993-09-10 | Pasteur Institut | Sequences de nucleotides codant pour une proteine a activite ureasique |
US5443832A (en) | 1990-04-16 | 1995-08-22 | Institut Swisse De Recherches Experimentales Sur Le Cancer | Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response |
CA2117490C (en) | 1992-02-26 | 2009-01-06 | Timothy L. Cover | Purified vacuolating toxin from helicobacter pylori and methods to use same |
US5859219A (en) | 1992-02-26 | 1999-01-12 | Vanderbilt University | Purified vacuolating toxin from Helicobacter pylori and methods to use same |
AU3630093A (en) * | 1992-03-02 | 1993-10-05 | Biocine S.P.A. | Helicobacter pylori proteins useful for vaccines and diagnostics |
MX9301706A (es) * | 1992-04-13 | 1994-05-31 | Oravax Inc | Composicion de vacuna para el tratamiento de la infeccion por helicobacter. |
DE69223615T2 (de) * | 1992-07-06 | 1998-04-09 | Nestle Sa | Lactobacillus Acidophilus enthaltende Antigastritis-Mittel |
US5733740A (en) | 1992-10-13 | 1998-03-31 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma |
US5403924A (en) | 1992-10-13 | 1995-04-04 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration |
US5972336A (en) | 1992-11-03 | 1999-10-26 | Oravax Merieux Co. | Urease-based vaccine against helicobacter infection |
NZ269124A (en) | 1993-07-27 | 1997-06-24 | Csl Ltd | Vaccine comprising helicobacter antigens and its use in treating such infections |
AUPM612494A0 (en) * | 1994-06-08 | 1994-06-30 | Csl Limited | Treatment or prevention of helicobacter infection |
DE19521312A1 (de) * | 1995-06-12 | 1996-12-19 | Max Planck Gesellschaft | Verfahren zur Identifizierung sekretorischer Gene aus Helicobacter pylori |
DE19521314A1 (de) * | 1995-06-12 | 1996-12-19 | Max Planck Gesellschaft | Adhärenzgen aus Helicobacter pylori und davon codiertes Polypeptid |
DE19535321A1 (de) * | 1995-09-22 | 1997-03-27 | Max Planck Gesellschaft | Neues Adhäsin aus Helicobacter pylori |
GB2307987A (en) * | 1995-12-06 | 1997-06-11 | Univ Manchester | Epitopes of the urease of Helicobacter pylori as dignostic agents; pharmaceuticals comprising such epitopes or the antibodies thereto |
FR2745186B1 (fr) * | 1996-02-26 | 1998-12-31 | Torossian Fernand Narbey | Complexe immunomodulateur et ses utilisations pour le traitement et la prevention des recidives des affections par helicobacter |
AU2304097A (en) * | 1996-04-05 | 1997-10-29 | Kieta Holding S.A. | Compositions and methods relating to drug discovery and detection and treatment of gastrointestinal diseases |
US20030069404A1 (en) * | 1996-11-14 | 2003-04-10 | Rainer Haas | Helicobacter antigens and corresponding DNA fragments |
US20030023066A1 (en) * | 1996-11-14 | 2003-01-30 | Rainer Haas | Helicobacter polypeptides and corresponding polynucleotide molecules |
US6248551B1 (en) * | 1997-03-28 | 2001-06-19 | Institut Pasteur | Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides |
US5985631A (en) * | 1997-09-12 | 1999-11-16 | Oravax-Merieux Co. | Method for preventing the activation of inactive, recombinant Helicobacter pylori apourease |
WO2001083531A1 (en) * | 2000-04-27 | 2001-11-08 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Method for identifying helicobacter antigens |
-
1994
- 1994-02-23 US US08/200,346 patent/US6290962B1/en not_active Expired - Fee Related
-
1995
- 1995-02-23 SK SK1094-96A patent/SK109496A3/sk unknown
- 1995-02-23 NZ NZ282535A patent/NZ282535A/en unknown
- 1995-02-23 PL PL95316007A patent/PL179149B1/pl not_active IP Right Cessation
- 1995-02-23 BR BR9506884A patent/BR9506884A/pt not_active Application Discontinuation
- 1995-02-23 EP EP95912583A patent/EP0751786A4/en not_active Withdrawn
- 1995-02-23 CZ CZ962503A patent/CZ250396A3/cs unknown
- 1995-02-23 CA CA002184057A patent/CA2184057A1/en not_active Abandoned
- 1995-02-23 AU AU19681/95A patent/AU694195C/en not_active Withdrawn - After Issue
- 1995-02-23 JP JP7522429A patent/JPH09509661A/ja active Pending
- 1995-02-23 WO PCT/US1995/002202 patent/WO1995022987A1/en not_active Application Discontinuation
- 1995-02-23 HU HU9602310A patent/HUT75374A/hu unknown
-
1996
- 1996-08-22 FI FI963281A patent/FI963281A/fi unknown
- 1996-08-22 NO NO963508A patent/NO963508L/no not_active Application Discontinuation
- 1996-08-23 OA OA60879A patent/OA10372A/fr unknown
-
2001
- 2001-09-18 US US09/955,739 patent/US20030007980A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BR9506884A (pt) | 1997-08-19 |
HUT75374A (en) | 1997-05-28 |
WO1995022987A1 (en) | 1995-08-31 |
NZ282535A (en) | 2001-03-30 |
NO963508L (no) | 1996-10-21 |
US6290962B1 (en) | 2001-09-18 |
EP0751786A1 (en) | 1997-01-08 |
PL179149B1 (pl) | 2000-07-31 |
JPH09509661A (ja) | 1997-09-30 |
US20030007980A1 (en) | 2003-01-09 |
AU694195B2 (en) | 1998-07-16 |
OA10372A (en) | 2001-11-14 |
HU9602310D0 (en) | 1996-10-28 |
AU1968195A (en) | 1995-09-11 |
EP0751786A4 (en) | 1999-12-29 |
AU694195C (en) | 2001-07-19 |
FI963281A (fi) | 1996-10-22 |
CZ250396A3 (en) | 1996-12-11 |
NO963508D0 (no) | 1996-08-22 |
SK109496A3 (en) | 1997-07-09 |
CA2184057A1 (en) | 1995-08-31 |
PL316007A1 (en) | 1996-12-23 |
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