FI953442A0 - Frystorkade kulor innehållande gonadotropin - Google Patents

Frystorkade kulor innehållande gonadotropin

Info

Publication number
FI953442A0
FI953442A0 FI953442A FI953442A FI953442A0 FI 953442 A0 FI953442 A0 FI 953442A0 FI 953442 A FI953442 A FI 953442A FI 953442 A FI953442 A FI 953442A FI 953442 A0 FI953442 A0 FI 953442A0
Authority
FI
Finland
Prior art keywords
pct
freeze
beads containing
dried beads
gonadotropin
Prior art date
Application number
FI953442A
Other languages
English (en)
Finnish (fi)
Other versions
FI953442A (sv
FI112324B (sv
Inventor
Arnold Titus Philip Skrabanja
Herman Vromans
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of FI953442A publication Critical patent/FI953442A/sv
Publication of FI953442A0 publication Critical patent/FI953442A0/sv
Application granted granted Critical
Publication of FI112324B publication Critical patent/FI112324B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI953442A 1993-04-28 1995-07-14 Förfarande för framställning av gonadotropin innehållande lyosfär FI112324B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP93201215 1993-04-28
EP93201215 1993-04-28
PCT/EP1994/001303 WO1994025005A1 (en) 1993-04-28 1994-04-25 Lyospheres comprising gonadotropin
EP9401303 1994-04-25

Publications (3)

Publication Number Publication Date
FI953442A FI953442A (sv) 1995-07-14
FI953442A0 true FI953442A0 (sv) 1995-07-14
FI112324B FI112324B (sv) 2003-11-28

Family

ID=8213798

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953442A FI112324B (sv) 1993-04-28 1995-07-14 Förfarande för framställning av gonadotropin innehållande lyosfär

Country Status (16)

Country Link
US (1) US5656597A (sv)
EP (1) EP0695171B1 (sv)
JP (1) JPH08509483A (sv)
KR (1) KR100334856B1 (sv)
AT (1) ATE146360T1 (sv)
AU (1) AU679986B2 (sv)
CA (1) CA2150251C (sv)
DE (1) DE69401204T2 (sv)
DK (1) DK0695171T3 (sv)
ES (1) ES2098140T3 (sv)
FI (1) FI112324B (sv)
GR (1) GR3022510T3 (sv)
HK (1) HK1002017A1 (sv)
NO (1) NO311168B1 (sv)
NZ (1) NZ265956A (sv)
WO (1) WO1994025005A1 (sv)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
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IL120202A (en) * 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
GB2329124B (en) * 1997-09-12 2002-05-08 Hiran Asoka Malinga Ratwatte Method of forming dose units of active agents
DK1165050T3 (da) * 1999-04-05 2006-05-01 Mannkind Corp Fremgangsmåde til dannelse af fint pulver
EP1658840A1 (en) * 1999-04-05 2006-05-24 Mannkind Corporation Methods for fine powder formation
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
ES2300568T3 (es) 2002-03-20 2008-06-16 Mannkind Corporation Aparato de inhalacion.
US20040248784A1 (en) * 2003-06-03 2004-12-09 Marco Filicori Unitary combinations of FSH and hCG
JP2007522085A (ja) * 2003-06-27 2007-08-09 スミスクライン・ビーチャム・コーポレイション 安定化されたトポテカンリポソーム組成物および方法
DE602005024413D1 (de) 2004-08-20 2010-12-09 Mannkind Corp Katalyse der diketopiperazinsynthese
AU2005277041B2 (en) 2004-08-23 2012-03-22 Mannkind Corporation Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery
US7799344B2 (en) 2005-09-14 2010-09-21 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
CN104383546B (zh) 2006-02-22 2021-03-02 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
TWI436789B (zh) 2008-01-21 2014-05-11 Intervet Int Bv 含有藥學化合物的顆粒之冷凍乾燥方法及含有此顆粒的藥學包
KR101695800B1 (ko) 2008-03-05 2017-02-22 사노피 파스퇴르 항원보강제 함유 백신 조성물의 안정화 방법
CN101269215B (zh) * 2008-05-15 2011-03-23 上海天伟生物制药有限公司 一种糖蛋白激素组合物
US8499757B2 (en) 2008-06-13 2013-08-06 Mannkind Corporation Dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR20190090092A (ko) 2009-06-12 2019-07-31 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送***和方法
BR122020008875B8 (pt) 2011-04-01 2022-12-06 Mannkind Corp Embalagem de bolha e método de fabricação de uma embalagem de bolhas
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
CA2906817C (en) 2013-03-15 2022-01-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
CN105517607A (zh) 2013-08-05 2016-04-20 曼金德公司 吹入设备和方法
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
JP6855469B2 (ja) * 2015-10-16 2021-04-07 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 消化器標的療法のための処方物を調製するための工程

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932943A (en) * 1970-08-14 1976-01-20 E. I. Du Pont De Nemours And Company Method of preparation of lyophilized biological products
EP0081913B1 (en) * 1981-12-11 1985-06-26 JOHN WYETH & BROTHER LIMITED Process and apparatus for freezing a liquid medium
JPS60258125A (ja) * 1984-06-06 1985-12-20 Hayashibara Biochem Lab Inc 蛋白性生理活性物質を含有する水溶性乾燥物
ATE99546T1 (de) * 1989-05-01 1994-01-15 Alkermes Inc Verfahren zur herstellung von kleinen partikeln von biologisch aktiven molekuelen.
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations

Also Published As

Publication number Publication date
AU6648894A (en) 1994-11-21
FI953442A (sv) 1995-07-14
GR3022510T3 (en) 1997-05-31
NO311168B1 (no) 2001-10-22
KR950703934A (ko) 1995-11-17
HK1002017A1 (en) 1998-07-24
NZ265956A (en) 1996-09-25
EP0695171A1 (en) 1996-02-07
ES2098140T3 (es) 1997-04-16
DE69401204T2 (de) 1997-06-05
CA2150251C (en) 2005-02-22
ATE146360T1 (de) 1997-01-15
KR100334856B1 (ko) 2002-11-07
WO1994025005A1 (en) 1994-11-10
DK0695171T3 (da) 1997-06-02
US5656597A (en) 1997-08-12
NO954320D0 (no) 1995-10-27
JPH08509483A (ja) 1996-10-08
CA2150251A1 (en) 1994-11-10
EP0695171B1 (en) 1996-12-18
AU679986B2 (en) 1997-07-17
DE69401204D1 (de) 1997-01-30
FI112324B (sv) 2003-11-28
NO954320L (no) 1995-10-27

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