FI925745A - Interleukin-6-kompositioner och foerfarande foer deras framstaellning - Google Patents

Interleukin-6-kompositioner och foerfarande foer deras framstaellning Download PDF

Info

Publication number: FI925745A
Authority: FI; Finland
Prior art keywords: human interleukin; interleukin; faring; framstaellning; composition
Prior art date: 1991-04-18

Application number

FI925745A

Other languages

English (en)

Other versions

FI925745A0 (fi

Inventor

Shingou Sakurai

Masanobu Naruto

Makoto Kihara

Keizo Hanada

Emiko Sano

Shigeru Ichikura

Jun Utsumi

Kazuo Hosoi

Original Assignee

Toray Industries

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-18

Filing date

1992-12-17

Publication date

1992-12-17

1992-12-17 Application filed by Toray Industries filed Critical Toray Industries

1992-12-17 Publication of FI925745A publication Critical patent/FI925745A/fi

1992-12-17 Publication of FI925745A0 publication Critical patent/FI925745A0/fi

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/204—IL-6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5412—IL-6
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0656—Adult fibroblasts

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Analytical Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Toxicology (AREA)
Microbiology (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Inorganic Chemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI925745A 1991-04-18 1992-12-17 Interleukin-6-kompositioner och foerfarande foer deras framstaellning FI925745A0 (fi)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP8660291		1991-04-18
JP8828491		1991-04-19
PCT/JP1992/000487 WO1992018537A1 (fr)	1991-04-18	1992-04-17	Composition a base d'interleukine 6 et procede de production

Publications (2)

Publication Number	Publication Date
FI925745A true FI925745A (fi)	1992-12-17
FI925745A0 FI925745A0 (fi)	1992-12-17

Family

ID=26427716

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI925745A FI925745A0 (fi)	1991-04-18	1992-12-17	Interleukin-6-kompositioner och foerfarande foer deras framstaellning

Country Status (10)

Country	Link
EP (1)	EP0550756B1 (fi)
KR (1)	KR930700550A (fi)
AT (1)	ATE210150T1 (fi)
AU (1)	AU1554592A (fi)
CA (1)	CA2085744A1 (fi)
DE (1)	DE69232259T2 (fi)
ES (1)	ES2164050T3 (fi)
FI (1)	FI925745A0 (fi)
TW (1)	TW221379B (fi)
WO (1)	WO1992018537A1 (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5338834A (en) *	1993-01-26	1994-08-16	Allelix Biopharmaceuticals Inc.	Ultrapure human interleukin-6
ES2252876T5 (es)	1997-12-03	2014-04-03	Roche Diagnostics Gmbh	Proceso para preparar polipéptidos con glicolización adecuada
AU771908C (en)	1998-12-09	2005-03-10	Phyton Holdings, Llc	A method for manufacturing glycoproteins having human-type glycosylation
ATE478150T1 (de)	1999-10-26	2010-09-15	Stichting Dienst Landbouwkundi	Säugetierartige glykosylierung in pflanzen
JP2005505234A (ja)	2001-01-19	2005-02-24	ザ　ダウ　ケミカル　カンパニー	植物細胞によるヒト型糖鎖をもつ糖タンパク質の分泌生産方法
KR101196023B1 (ko)	2002-03-19	2012-10-30	스티칭 디엔스트 랜드보위쿤디그 온데조에크	식물에서 글리칸 프로세싱의 최적화
EP1485492B1 (en)	2002-03-19	2011-12-21	Stichting Dienst Landbouwkundig Onderzoek	Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants
CL2003002461A1 (es)	2002-11-27	2005-01-07	Dow Chemical Company Agroscien	Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
CN101702919B (zh)	2007-04-17	2014-08-13	基金会农业研究服务中心	植物通过表达非哺乳动物糖基转移酶而表现出哺乳动物类型的糖基化作用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6062997A (ja) *	1983-09-17	1985-04-11	Mochida Pharmaceut Co Ltd	インタ−フエロンの生産方法
DE3519011A1 (de) *	1985-05-25	1986-11-27	Behringwerke Ag, 3550 Marburg	Verfahren zur herstellung eines materials zur affinitaetschromatographie
JPS62153755A (ja) *	1985-12-27	1987-07-08	Showa Denko Kk	クロマトグラフイ−用吸着担体
JP2648860B2 (ja) *	1986-05-08	1997-09-03	イエダリサーチアンドデベロップメントコンパニーリミテッド	ヒトインターフエロン−β２Ａ及びヒトインターフエロン−β２Ｂ、該インターフエロンをコードする遺伝子を含むベクター、該インターフエロンを産生するセルライン及び該インターフエロンの医薬品としての用途
IE67035B1 (en) *	1986-07-08	1996-02-21	Genetics Inst	Production and use of non-glycosylated IL-6
JP2676336B2 (ja) *	1986-08-06	1997-11-12	忠三岸本	ヒトｂ細胞分化因子の遺伝子
JPS63150297A (ja) *	1986-12-12	1988-06-22	Ajinomoto Co Inc	新規ｂ細胞分化因子蛋白標品
EP0315782B1 (de) *	1987-10-13	1994-09-28	Dr. Karl Thomae GmbH	Verfahren zur Herstellung von Proteinen
JPH03133935A (ja) *	1989-10-19	1991-06-07	Toray Ind Inc	ヒト天然型インターロイキン６組成物

1992
- 1992-04-17 AT AT92908258T patent/ATE210150T1/de not_active IP Right Cessation
- 1992-04-17 WO PCT/JP1992/000487 patent/WO1992018537A1/ja active IP Right Grant
- 1992-04-17 AU AU15545/92A patent/AU1554592A/en not_active Abandoned
- 1992-04-17 DE DE69232259T patent/DE69232259T2/de not_active Expired - Fee Related
- 1992-04-17 EP EP92908258A patent/EP0550756B1/en not_active Expired - Lifetime
- 1992-04-17 CA CA002085744A patent/CA2085744A1/en not_active Abandoned
- 1992-04-17 ES ES92908258T patent/ES2164050T3/es not_active Expired - Lifetime
- 1992-04-30 TW TW081103408A patent/TW221379B/zh active
- 1992-12-16 KR KR1019920703255A patent/KR930700550A/ko not_active Application Discontinuation
- 1992-12-17 FI FI925745A patent/FI925745A0/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0550756A4 (fi)	1994-04-27
ES2164050T3 (es)	2002-02-16
DE69232259T2 (de)	2002-06-13
ATE210150T1 (de)	2001-12-15
EP0550756A1 (en)	1993-07-14
AU1554592A (en)	1992-11-17
DE69232259D1 (de)	2002-01-17
FI925745A0 (fi)	1992-12-17
WO1992018537A1 (fr)	1992-10-29
TW221379B (fi)	1994-03-01
KR930700550A (ko)	1993-03-15
EP0550756B1 (en)	2001-12-05
CA2085744A1 (en)	1992-10-19

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Legal Events

Date	Code	Title	Description
1997-11-10	FD	Application lapsed