FI921595A0 - Rapamycinkarbamater. - Google Patents

Rapamycinkarbamater.

Info

Publication number: FI921595A0
Authority: FI; Finland
Prior art keywords: rapamycinkarbamater
Prior art date: 1991-04-17

Application number

FI921595A

Other languages

English (en)

Other versions

FI921595A (fi

Inventor

Wenling Kao

Robert Lewis Vogel

John Henry Musser

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-17

Filing date

1992-04-10

Publication date

1992-04-10

1991-04-17 Priority claimed from US07/686,728 external-priority patent/US5118678A/en

1992-02-18 Priority claimed from US07/837,048 external-priority patent/US5194447A/en

1992-04-10 Application filed by American Home Prod filed Critical American Home Prod

1992-04-10 Publication of FI921595A0 publication Critical patent/FI921595A0/fi

1992-10-18 Publication of FI921595A publication Critical patent/FI921595A/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI921595A 1991-04-17 1992-04-10 Rapamycinkarbamater FI921595A (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/686,728 US5118678A (en)	1991-04-17	1991-04-17	Carbamates of rapamycin
US07/837,048 US5194447A (en)	1992-02-18	1992-02-18	Sulfonylcarbamates of rapamycin

Publications (2)

Publication Number	Publication Date
FI921595A0 true FI921595A0 (fi)	1992-04-10
FI921595A FI921595A (fi)	1992-10-18

Family

ID=27103855

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI921595A FI921595A (fi)	1991-04-17	1992-04-10	Rapamycinkarbamater

Country Status (12)

Country	Link
EP (1)	EP0509795A2 (fi)
JP (1)	JPH05112573A (fi)
KR (1)	KR920019798A (fi)
AU (1)	AU642592B2 (fi)
CZ (1)	CZ117392A3 (fi)
FI (1)	FI921595A (fi)
HU (1)	HU9201254D0 (fi)
IE (1)	IE921249A1 (fi)
MX (1)	MX9201710A (fi)
NO (1)	NO921449L (fi)
NZ (1)	NZ242367A (fi)
SK (1)	SK117392A3 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5776943A (en) *	1991-05-14	1998-07-07	American Home Products Corporation	Rapamycin metabolites
US5118677A (en) *	1991-05-20	1992-06-02	American Home Products Corporation	Amide esters of rapamycin
MX9301188A (es) *	1992-03-05	1994-07-29	American Home Prod	Nuevos sulfonatos y 42-(n-carboalcoxi)sulfamatos en posicion 42 de la rapamicina, procedimiento para su preparacion y composicion farmaceutica que los comprende.
GB9307491D0 (en) *	1993-04-08	1993-06-02	Sandoz Ltd	Organic compounds
CH686761A5 (de)	1993-05-27	1996-06-28	Sandoz Ag	Galenische Formulierungen.
US5527907A (en) *	1993-11-19	1996-06-18	Abbott Laboratories	Macrolide immunomodulators
CA2175215C (en) *	1993-11-19	2008-06-03	Yat Sun Or	Semisynthetic analogs of rapamycin (macrolides) being immunomodulators
US5362718A (en)	1994-04-18	1994-11-08	American Home Products Corporation	Rapamycin hydroxyesters
US8124630B2 (en)	1999-01-13	2012-02-28	Bayer Healthcare Llc	ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
ATE556713T1 (de)	1999-01-13	2012-05-15	Bayer Healthcare Llc	Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer
MXPA02001657A (es) *	1999-08-18	2002-12-13	Wyeth Corp	Esteres de 40-0-(2-hidroxi)etil-rapamicina hidrosolubles.
AU2003209116A1 (en)	2002-02-11	2003-09-04	Bayer Pharmaceuticals Corporation	Aryl ureas with angiogenesis inhibiting activity
US7557129B2 (en)	2003-02-28	2009-07-07	Bayer Healthcare Llc	Cyanopyridine derivatives useful in the treatment of cancer and other disorders
JP4860474B2 (ja)	2003-05-20	2012-01-25	バイエル、ファーマシューテイカルズ、コーポレイション	Ｐｄｇｆｒによって仲介される病気のためのジアリール尿素
DK1663978T3 (da)	2003-07-23	2008-04-07	Bayer Pharmaceuticals Corp	Fluorsubstitueret omega-carboxyaryl-diphenylurinstof til behandling og forebyggelse af sygdomme og lidelser
WO2005042567A1 (en) *	2003-11-03	2005-05-12	Altachem Pharma Ltd.	Rapamycin peptides conjugates: synthesis and uses thereof
US8021849B2 (en)	2004-11-05	2011-09-20	Siemens Healthcare Diagnostics Inc.	Methods and kits for the determination of sirolimus in a sample
CN101137659A (zh)	2005-03-07	2008-03-05	惠氏公司	42-o-（2-羟基）乙基-雷帕霉素的氧杂环庚烷异构体
US7189582B2 (en)	2005-04-27	2007-03-13	Dade Behring Inc.	Compositions and methods for detection of sirolimus
KR20210131329A (ko) *	2019-01-25	2021-11-02	노드테라 리미티드	카르바메이트 유도체 및 이의 용도

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4885171A (en) *	1978-11-03	1989-12-05	American Home Products Corporation	Use of rapamycin in treatment of certain tumors
US4316885A (en) *	1980-08-25	1982-02-23	Ayerst, Mckenna And Harrison, Inc.	Acyl derivatives of rapamycin
US4650803A (en) *	1985-12-06	1987-03-17	University Of Kansas	Prodrugs of rapamycin
WO1991002736A1 (en) *	1989-08-18	1991-03-07	Fisons Plc	Macrocyclic compounds
PT98990A (pt) *	1990-09-19	1992-08-31	American Home Prod	Processo para a preparacao de esteres de acidos carboxilicos de rapamicina
US5118677A (en) *	1991-05-20	1992-06-02	American Home Products Corporation	Amide esters of rapamycin

1992
- 1992-04-10 NO NO92921449A patent/NO921449L/no unknown
- 1992-04-10 FI FI921595A patent/FI921595A/fi unknown
- 1992-04-10 JP JP4090825A patent/JPH05112573A/ja active Pending
- 1992-04-11 KR KR1019920006033A patent/KR920019798A/ko not_active Application Discontinuation
- 1992-04-13 MX MX9201710A patent/MX9201710A/es unknown
- 1992-04-13 HU HU9201254A patent/HU9201254D0/hu unknown
- 1992-04-14 AU AU14880/92A patent/AU642592B2/en not_active Ceased
- 1992-04-15 NZ NZ24236792A patent/NZ242367A/en unknown
- 1992-04-15 EP EP19920303401 patent/EP0509795A2/en not_active Withdrawn
- 1992-04-16 IE IE124992A patent/IE921249A1/en not_active Application Discontinuation
- 1992-04-16 SK SK1173-92A patent/SK117392A3/sk unknown
- 1992-04-16 CZ CS921173A patent/CZ117392A3/cs unknown

Also Published As

Publication number	Publication date
JPH05112573A (ja)	1993-05-07
HU9201254D0 (en)	1992-07-28
SK117392A3 (en)	1995-04-12
AU1488092A (en)	1992-10-22
NO921449L (no)	1992-10-19
FI921595A (fi)	1992-10-18
AU642592B2 (en)	1993-10-21
EP0509795A2 (en)	1992-10-21
CZ117392A3 (en)	1993-09-15
IE921249A1 (en)	1992-10-21
EP0509795A3 (fi)	1994-03-23
KR920019798A (ko)	1992-11-20
NZ242367A (en)	1994-07-26
MX9201710A (es)	1993-01-01
NO921449D0 (no)	1992-04-10

Publication	Publication Date	Title
DE122006000020I1 (de)	2011-12-01	Aerosolpraparate.
DE59201883D1 (de)	1995-05-18	Tilger.
FI921595A0 (fi)	1992-04-10	Rapamycinkarbamater.
DE59105384D1 (de)	1995-06-08	Anomaloskop.
FI912432A0 (fi)	1991-05-20	Matningsanordning.
FI920546A0 (fi)	1992-02-10	Centralvaermeenhet.
FI915574A0 (fi)	1991-11-26	Eldslaeckningsanordning.
ES1018229Y (es)	1993-01-01	Bovedilla.
ES1016842Y (es)	1992-06-01	Carpeta-agenda.
ES1017618Y (es)	1992-07-16	Flexometro-trazador.
ES1017798Y (es)	1992-07-01	Garfio-soporte.
ES1018067Y (es)	1992-08-16	Tarjeta-puzzle.
ES1015938Y (es)	1992-04-01	Pizarro-calendario.
FI86243B (fi)	1992-04-30	Foervaringskaerl foer vattendjur saosom fiskar.
ES1016478Y (es)	1992-04-16	Papelera pefeccionada.
ES1019520Y (es)	1992-11-16	Lapida funeraria.
ES1018836Y (es)	1992-10-01	Cisterna-remolque.
ES1018708Y (es)	1992-09-16	Batidora-mezcladora.
ES1018322Y (es)	1992-08-01	Hidrocompresor.
FI910101A0 (fi)	1991-01-08	Foersaeljningsstaell.
FI910071A0 (fi)	1991-01-07	Slutet lufttransportfoerfarande.
FI910132A0 (fi)	1991-01-10	Precisionskapsaog.
FI910103A0 (fi)	1991-01-08	Kombinerad centralvaermepanna-vaermevattenackumulator.
FI910068A (fi)	1992-07-08	Faestmekanism foer varohylla.
FI910094A0 (fi)	1991-01-08	Boggidrev.