FI905589A0 - N-substituerade derivat av 3r, 4r-etyl -((1-metyl-1h-imidazol-5-yl) metyl)-2-pyrrolidinon. - Google Patents

N-substituerade derivat av 3r, 4r-etyl -((1-metyl-1h-imidazol-5-yl) metyl)-2-pyrrolidinon.

Info

Publication number
FI905589A0
FI905589A0 FI905589A FI905589A FI905589A0 FI 905589 A0 FI905589 A0 FI 905589A0 FI 905589 A FI905589 A FI 905589A FI 905589 A FI905589 A FI 905589A FI 905589 A0 FI905589 A0 FI 905589A0
Authority
FI
Finland
Prior art keywords
methyl
derivat
pyrrolidinone
imidazol
substitute
Prior art date
Application number
FI905589A
Other languages
English (en)
Inventor
Pamela Albaugh
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of FI905589A0 publication Critical patent/FI905589A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FI905589A 1989-11-13 1990-11-12 N-substituerade derivat av 3r, 4r-etyl -((1-metyl-1h-imidazol-5-yl) metyl)-2-pyrrolidinon. FI905589A0 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/434,929 US5264449A (en) 1989-11-13 1989-11-13 N-substituted derivatives of 3R,4R-ethyl-[(1-methyl-1H-imidazol-5-yl)methyl]-2-pyrrolidinone

Publications (1)

Publication Number Publication Date
FI905589A0 true FI905589A0 (fi) 1990-11-12

Family

ID=23726283

Family Applications (1)

Application Number Title Priority Date Filing Date
FI905589A FI905589A0 (fi) 1989-11-13 1990-11-12 N-substituerade derivat av 3r, 4r-etyl -((1-metyl-1h-imidazol-5-yl) metyl)-2-pyrrolidinon.

Country Status (15)

Country Link
US (1) US5264449A (fi)
EP (1) EP0429232A1 (fi)
JP (1) JPH03188075A (fi)
CN (1) CN1026589C (fi)
AU (1) AU631025B2 (fi)
CA (1) CA2027604A1 (fi)
FI (1) FI905589A0 (fi)
HU (1) HU207512B (fi)
IE (1) IE904067A1 (fi)
IL (1) IL96088A (fi)
NO (1) NO177056C (fi)
NZ (1) NZ235735A (fi)
PT (1) PT95874A (fi)
RU (1) RU2015978C1 (fi)
ZA (1) ZA908386B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5453434A (en) * 1989-11-13 1995-09-26 Allergan, Inc. N-substituted derivatives of 3R,4R-ethyl-[(1-methyl-1H-imidazol-5-yl)methyl]-2-pyrrolidone
DK0618913T3 (da) * 1991-12-18 1996-10-14 Schering Corp Imidazolyl eller imidazoylalkyl substitueret med en 4- eller 5-leddet nitrogenholdig heterocyclisk ring
CA2125060C (en) * 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
US5677327A (en) * 1995-06-22 1997-10-14 Allergan Method for identifying muscarinic agents lacking miotic side effects
US6001835A (en) * 1996-04-03 1999-12-14 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
AU717298B2 (en) * 1996-04-03 2000-03-23 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP2000507585A (ja) * 1996-04-03 2000-06-20 メルク エンド カンパニー インコーポレーテッド ファルネシルタンパク質トランスフェラーゼの阻害剤
US5675038A (en) * 1996-07-18 1997-10-07 Allergan Lithium and amine dissolving metal reduction
US5675019A (en) * 1996-07-18 1997-10-07 Allergan Process for making piloloctam and derivatives thereof
US5800807A (en) * 1997-01-29 1998-09-01 Bausch & Lomb Incorporated Ophthalmic compositions including glycerin and propylene glycol
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US7132444B2 (en) * 2002-01-07 2006-11-07 Sun Pharmaceutical Industries, Ltd. Process for the preparation of trans-3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(4-methyl cyclohexyl) amino]carbonyl]amino]sulfonyl] phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide
CN104211638A (zh) * 2014-08-13 2014-12-17 李增 一种脂肪氨基取代的芸香碱类衍生物及其制备和作为抗阿尔兹海默症的药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470197A (en) * 1967-08-30 1969-09-30 Miles Lab 1-substituted derivatives of 3-ethyl-4 - (1-methylimidazolyl-(5)-methyl)-2-pyrrolidinone
US5055467A (en) * 1989-11-13 1991-10-08 Allergan, Inc. Pharmaceutical epinephrine-pilocarpine compounds

Also Published As

Publication number Publication date
US5264449A (en) 1993-11-23
CN1051730A (zh) 1991-05-29
HUT56360A (en) 1991-08-28
NO904901D0 (no) 1990-11-12
NO177056C (no) 1995-07-12
JPH03188075A (ja) 1991-08-16
AU6652890A (en) 1991-05-16
HU907116D0 (en) 1991-05-28
AU631025B2 (en) 1992-11-12
NZ235735A (en) 1992-03-26
EP0429232A1 (en) 1991-05-29
NO177056B (no) 1995-04-03
IE904067A1 (en) 1991-05-22
IL96088A (en) 1995-03-30
HU207512B (en) 1993-04-28
IL96088A0 (en) 1991-07-18
CN1026589C (zh) 1994-11-16
RU2015978C1 (ru) 1994-07-15
PT95874A (pt) 1991-09-13
ZA908386B (en) 1991-08-28
CA2027604A1 (en) 1991-05-14
NO904901L (no) 1991-05-14

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Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: ALLERGAN, INC.