FI900604A0 - Process for the preparation of a pharmaceutical composition containing cyclosporin - Google Patents

Process for the preparation of a pharmaceutical composition containing cyclosporin

Info

Publication number
FI900604A0
FI900604A0 FI900604A FI900604A FI900604A0 FI 900604 A0 FI900604 A0 FI 900604A0 FI 900604 A FI900604 A FI 900604A FI 900604 A FI900604 A FI 900604A FI 900604 A0 FI900604 A0 FI 900604A0
Authority
FI
Finland
Prior art keywords
preparation
pharmaceutical composition
composition containing
containing cyclosporin
cyclosporin
Prior art date
Application number
FI900604A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI97524B (en
FI97524C (en
Inventor
Birgit Hauer
Ulrich Posanski
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898902901A external-priority patent/GB8902901D0/en
Priority claimed from GB898902898A external-priority patent/GB8902898D0/en
Priority claimed from GB898903147A external-priority patent/GB8903147D0/en
Priority claimed from GB898903663A external-priority patent/GB8903663D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI900604A0 publication Critical patent/FI900604A0/en
Publication of FI97524B publication Critical patent/FI97524B/en
Application granted granted Critical
Publication of FI97524C publication Critical patent/FI97524C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
FI900604A 1989-02-09 1990-02-07 Process for the preparation of a pharmaceutical composition containing cyclosporin FI97524C (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB898902901A GB8902901D0 (en) 1989-02-09 1989-02-09 Improvements in or relating to organic compounds
GB8902901 1989-02-09
GB898902898A GB8902898D0 (en) 1989-02-09 1989-02-09 Improvements in or relating to organic compounds
GB8902898 1989-02-09
GB898903147A GB8903147D0 (en) 1989-02-13 1989-02-13 Improvements in or relating to organic compounds
GB8903147 1989-02-13
GB898903663A GB8903663D0 (en) 1989-02-17 1989-02-17 Improvements in or relating to organic compounds
GB8903663 1989-02-17

Publications (3)

Publication Number Publication Date
FI900604A0 true FI900604A0 (en) 1990-02-07
FI97524B FI97524B (en) 1996-09-30
FI97524C FI97524C (en) 1997-01-10

Family

ID=27450262

Family Applications (1)

Application Number Title Priority Date Filing Date
FI900604A FI97524C (en) 1989-02-09 1990-02-07 Process for the preparation of a pharmaceutical composition containing cyclosporin

Country Status (25)

Country Link
JP (3) JP3484190B2 (en)
KR (1) KR0170769B1 (en)
AT (1) AT404552B (en)
AU (1) AU630413B2 (en)
BE (1) BE1003009A5 (en)
CA (1) CA2009533C (en)
CH (1) CH679277A5 (en)
CY (1) CY1903A (en)
DE (1) DE4003844B4 (en)
DK (1) DK176209B1 (en)
ES (1) ES2021942A6 (en)
FI (1) FI97524C (en)
FR (1) FR2642650B1 (en)
GB (1) GB2230440B (en)
HK (1) HK37296A (en)
HU (1) HU213394B (en)
IT (1) IT1240758B (en)
LU (1) LU87675A1 (en)
MY (1) MY107377A (en)
NL (1) NL195028C (en)
NO (1) NO301576B1 (en)
NZ (1) NZ232401A (en)
PH (1) PH30917A (en)
PT (1) PT93079B (en)
SE (1) SE511398C2 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
HU208491B (en) * 1990-11-27 1993-11-29 Gyogyszerkutato Intezet Process for producing oral pharmaceutical composition containing cyclosporin
MX9201782A (en) † 1991-04-19 1992-10-01 Sandoz Ag PARTICLES OF BIOLOGICALLY ACTIVE SUBSTANCES, SUBSTANTIALLY INSOLUBLE IN WATER, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION THAT CONTAINS THEM.
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
EP0642332B1 (en) 1992-05-13 1997-01-15 Sandoz Ltd. Ophthalmic compositions containing a cyclosporin
US5759566A (en) * 1992-07-28 1998-06-02 Poli Industria Chimica Spa Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents
ES2168271T3 (en) 1992-09-25 2002-06-16 Novartis Ag PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINS.
DE4412201A1 (en) * 1993-04-20 1994-11-10 Rentschler Arzneimittel New pharmaceutical preparations for oral administration containing cyclosporin
PT697881E (en) † 1993-04-20 2002-10-31 Novartis Ag NEW PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINE FOR ORAL ADMINISTRATION
DE4340781C3 (en) * 1993-11-30 2000-01-27 Novartis Ag Liquid preparations containing cyclosporin and process for their preparation
KR0146671B1 (en) * 1994-02-25 1998-08-17 김충환 Cyclosporin-containing powder composition
JP3833248B2 (en) 1994-11-03 2006-10-11 ノバルティス・アクチエンゲゼルシャフト Novel formulation of cyclosporine for oral administration with simple composition and high bioavailability and process for its production
US5679566A (en) * 1995-01-20 1997-10-21 University Of Massachusetts Medical Center Yeast NMD2 gene
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
US5798333A (en) * 1996-09-17 1998-08-25 Sherman; Bernard C. Water-soluble concentrates containing cyclosporins
AU762247B2 (en) * 1997-01-30 2003-06-19 Novartis Ag Oil-free pharmaceutical compositions containing cyclosporin A
KR20040004416A (en) * 1997-01-30 2004-01-13 노파르티스 아게 Oil-Free Pharmaceutical Compositions Containing Cyclosporin A
ES2236891T3 (en) * 1997-03-12 2005-07-16 Abbott Laboratories HYDROFILE BINARY SYSTEMS FOR THE ADMINISTRATION OF CYCLOSPORINE.
NZ328751A (en) * 1997-09-16 1999-01-28 Bernard Charles Sherman Solid medicament containing an anionic surfactant and cyclosporin
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
JP4521554B2 (en) * 2004-03-31 2010-08-11 マイラン製薬株式会社 Cyclosporine preparation
EP1959935A2 (en) * 2005-10-26 2008-08-27 Banner Pharmacaps Inc. Hydrophilic vehicle-based dual controlled release matrix system as capsule fill
JP5823093B2 (en) * 2006-03-28 2015-11-25 ジャヴェリン ファーマシューティカルズ インコーポレイテッド Low dose diclofenac and β-cyclodextrin formulation
US7495024B2 (en) 2006-08-07 2009-02-24 Via Pharmaceuticals, Inc. Phenylalkyl N-hydroxyureas for combating atherosclerotic plaque
DE102008059201A1 (en) 2008-11-27 2010-06-02 GÖPFERICH, Achim, Prof. Dr. In situ precipitating drug solutions
KR102146704B1 (en) 2018-04-13 2020-08-21 가천대학교 산학협력단 Cyclosporin a containing microstructures for transdermal and intradermal drug delivery
EP4166133A1 (en) * 2021-10-13 2023-04-19 Chugai Seiyaku Kabushiki Kaisha Composition containing peptide compound and surfactant

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI65914C (en) * 1978-03-07 1984-08-10 Sandoz Ag FRAMEWORK FOR PHARMACEUTICAL COMPOSITION OF CYCLOSPORINE A
JPS61280435A (en) * 1985-04-04 1986-12-11 Kanji Takada Lymph orienting preparation of cyclosporin
NL8600050A (en) * 1986-01-13 1987-08-03 Sanico Nv PHARMACEUTICAL PREPARATION WITH DELAYED DELIVERY OF THE ACTIVE SUBSTANCE AND METHOD FOR PREPARING IT.
GB8602372D0 (en) * 1986-01-31 1986-03-05 Sandoz Ltd Organic compounds
CA1290249C (en) * 1986-04-09 1991-10-08 Cetus Corporation COMBINATION THERAPY USING INTERLEUKIN-2 AND/OR INTERFERON-.beta. AND TUMOR NECROSIS FACTOR
IE873057L (en) * 1986-11-13 1988-05-13 Tretorn Ab Compositions and method for treatment of cancer using¹monoclonal antibody against gd3 ganglioside together eith¹il-2
EP0296122B1 (en) * 1987-06-17 1993-09-29 Sandoz Ag Cyclosporins and their use as pharmaceuticals
JP2536876B2 (en) * 1987-07-31 1996-09-25 寛治 高田 Dissolvable powder formulation of cyclosporine
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
HU205010B (en) * 1987-09-15 1992-03-30 Sandoz Ag Process for producing pharmaceutical compositions comprising compounds soluble up to 1 per cent and having medical activity
DE3830494B4 (en) * 1987-09-15 2006-05-18 Novartis Ag Water-soluble monoesters as solubilizers for pharmacologically active substances and pharmaceutical excipients
JP2792862B2 (en) * 1988-07-30 1998-09-03 寛治 高田 Oral enteric formulation
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
JPH1038029A (en) * 1996-07-26 1998-02-13 Ebara Corp Dick shape structure with vibration damping function
JPH10280435A (en) * 1997-04-03 1998-10-20 Sekisui Chem Co Ltd Construction method of basement

Also Published As

Publication number Publication date
CA2009533A1 (en) 1990-08-09
IT9047609A1 (en) 1991-08-08
JPH02235817A (en) 1990-09-18
DE4003844B4 (en) 2007-09-20
NO900577D0 (en) 1990-02-07
NL195028C (en) 2003-12-02
SE9000441D0 (en) 1990-02-07
FI97524B (en) 1996-09-30
PH30917A (en) 1997-12-23
NL9000299A (en) 1990-09-03
DK176209B1 (en) 2007-02-05
CY1903A (en) 1996-11-22
HU900701D0 (en) 1990-04-28
KR0170769B1 (en) 1999-02-01
CA2009533C (en) 2002-11-12
NO900577L (en) 1990-08-10
CH679277A5 (en) 1992-01-31
NZ232401A (en) 1992-10-28
MY107377A (en) 1995-11-30
NL195028B (en) 2003-08-01
GB2230440B (en) 1993-05-19
DK32790A (en) 1990-08-10
GB9002504D0 (en) 1990-04-04
DE4003844A1 (en) 1990-08-16
DK32790D0 (en) 1990-02-07
JP4073641B2 (en) 2008-04-09
AU630413B2 (en) 1992-10-29
ATA27290A (en) 1998-05-15
FR2642650A1 (en) 1990-08-10
JP2001302538A (en) 2001-10-31
HU213394B (en) 1997-06-30
ES2021942A6 (en) 1991-11-16
NO301576B1 (en) 1997-11-17
IT1240758B (en) 1993-12-17
FR2642650B1 (en) 1994-12-09
AT404552B (en) 1998-12-28
BE1003009A5 (en) 1991-10-22
AU4925290A (en) 1990-08-16
KR900012625A (en) 1990-09-01
GB2230440A (en) 1990-10-24
IT9047609A0 (en) 1990-02-08
HK37296A (en) 1996-03-15
LU87675A1 (en) 1991-10-08
FI97524C (en) 1997-01-10
JP3484190B2 (en) 2004-01-06
PT93079A (en) 1990-08-31
PT93079B (en) 1996-04-30
SE9000441L (en) 1991-08-08
SE511398C2 (en) 1999-09-20
JP2006001947A (en) 2006-01-05

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: NOVARTIS AG

FG Patent granted

Owner name: NOVARTIS AG