FI893901A0 - Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi - Google Patents

Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi

Info

Publication number
FI893901A0
FI893901A0 FI893901A FI893901A FI893901A0 FI 893901 A0 FI893901 A0 FI 893901A0 FI 893901 A FI893901 A FI 893901A FI 893901 A FI893901 A FI 893901A FI 893901 A0 FI893901 A0 FI 893901A0
Authority
FI
Finland
Prior art keywords
alkyl
tetracyclic antidepressants
different substituents
substituents
preparing
Prior art date
Application number
FI893901A
Other languages
English (en)
Swedish (sv)
Other versions
FI91638B (fi
FI91638C (fi
FI893901A (fi
Inventor
Johannes Hubertus Wieringa
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI893901A0 publication Critical patent/FI893901A0/fi
Publication of FI893901A publication Critical patent/FI893901A/fi
Publication of FI91638B publication Critical patent/FI91638B/fi
Application granted granted Critical
Publication of FI91638C publication Critical patent/FI91638C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI893901A 1988-08-26 1989-08-18 Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi FI91638C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8802109 1988-08-26
NL8802109 1988-08-26

Publications (4)

Publication Number Publication Date
FI893901A0 true FI893901A0 (fi) 1989-08-18
FI893901A FI893901A (fi) 1990-02-27
FI91638B FI91638B (fi) 1994-04-15
FI91638C FI91638C (fi) 1994-07-25

Family

ID=19852805

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893901A FI91638C (fi) 1988-08-26 1989-08-18 Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi

Country Status (16)

Country Link
US (1) US4977158A (fi)
EP (1) EP0357126B1 (fi)
JP (1) JP2521157B2 (fi)
KR (1) KR900003177A (fi)
AT (1) ATE104981T1 (fi)
AU (1) AU618392B2 (fi)
CA (1) CA1325807C (fi)
DE (1) DE68914917T2 (fi)
DK (1) DK415789A (fi)
ES (1) ES2056194T3 (fi)
FI (1) FI91638C (fi)
IE (1) IE62754B1 (fi)
MX (1) MX9203809A (fi)
NZ (1) NZ230128A (fi)
PT (1) PT91555B (fi)
ZA (1) ZA895623B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT726265E (pt) * 1995-02-08 2001-12-28 Novartis Ag 10-amino-alifatil-dibenzo¬b,f| oxepinas com accao antineurodegenerativa
WO1999032108A1 (en) * 1997-12-19 1999-07-01 Akzo Nobel N.V. Org-5222 in the treatment of depression
HRP20020305A8 (en) 2002-04-10 2009-03-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20020440B1 (en) 2002-05-21 2008-02-29 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
HRP20020452A2 (en) 2002-05-23 2004-02-29 Pliva D D 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
HRP20030956A2 (en) * 2003-11-21 2005-08-31 Pliva-Istra�iva�ki institut d.o.o. USE OF 1,2-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANU
JP5245428B2 (ja) * 2007-07-06 2013-07-24 住友化学株式会社 トランス−ジベンゾオキセノピロール化合物の製造方法およびその中間体
US20090233959A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation Beloxepin and analogs for the treatment of pain
US20090233958A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (+)-beloxepin and methods for its synthesis and use
CA2715192A1 (en) * 2008-02-19 2009-08-27 Adolor Corporation Beloxepin, its enantiomers, and analogs thereof for the treatment of pain
US20090233957A1 (en) * 2008-02-19 2009-09-17 Adolor Corporation (-)-beloxepin and methods for its synthesis and use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4158059A (en) * 1976-05-24 1979-06-12 Akzona Incorporated Tension reducing 2,3,4,4a,9,136-hexahydro-dibenz[1,2;5,6]cyclohepta[3,4-c]py
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
US4271177A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 2,3,3a,12b-Tetrahydro-1H-dibenzo[2,3;6,7]thiepino[4,5-c]pyrroles and pharmaceutical use thereof
US4271179A (en) * 1976-05-24 1981-06-02 Akzona Incorporated 1,2,3,3a,8,12b-Hexahydro-dibenzo[1,2;5,6]cyclohepta[3,4-C]pyrroles and pharmaceutical use thereof
EP0270692A4 (en) * 1986-06-26 1990-12-12 Kyowa Hakko Kogyo Co., Ltd. Antiarrhythmic agent

Also Published As

Publication number Publication date
MX9203809A (es) 1992-07-01
PT91555B (pt) 1995-05-04
DE68914917T2 (de) 1994-08-11
AU4002289A (en) 1990-03-01
DE68914917D1 (de) 1994-06-01
IE62754B1 (en) 1995-02-22
FI91638B (fi) 1994-04-15
EP0357126B1 (en) 1994-04-27
IE892363L (en) 1990-02-26
KR900003177A (ko) 1990-03-23
NZ230128A (en) 1990-10-26
ES2056194T3 (es) 1994-10-01
DK415789A (da) 1990-02-27
AU618392B2 (en) 1991-12-19
US4977158A (en) 1990-12-11
EP0357126A1 (en) 1990-03-07
FI91638C (fi) 1994-07-25
JPH02111776A (ja) 1990-04-24
JP2521157B2 (ja) 1996-07-31
PT91555A (pt) 1990-03-08
ATE104981T1 (de) 1994-05-15
FI893901A (fi) 1990-02-27
ZA895623B (en) 1990-05-30
DK415789D0 (da) 1989-08-23
CA1325807C (en) 1994-01-04

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: AKZO N.V.