FI892131A0 - Analoger till underenheter av bordetellatoxin, vilka haerstammar fraon hybrid-dna. - Google Patents

Analoger till underenheter av bordetellatoxin, vilka haerstammar fraon hybrid-dna.

Info

Publication number: FI892131A0
Authority: FI; Finland
Prior art keywords: underenheter; haerstammar; bordetellatoxin; analoger; vilka
Prior art date: 1987-09-04

Application number

FI892131A

Other languages

English (en)

Other versions

FI101632B1 (fi

FI892131A (fi

FI101632B (fi

Inventor

Iii Walter Neal Burnette

Original Assignee

Amgen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-04

Filing date

1989-05-03

Publication date

1989-05-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26788722&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI892131(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1989-05-03 Application filed by Amgen Inc filed Critical Amgen Inc

1989-05-03 Publication of FI892131A publication Critical patent/FI892131A/fi

1989-05-03 Publication of FI892131A0 publication Critical patent/FI892131A0/fi

1998-07-31 Application granted granted Critical

1998-07-31 Publication of FI101632B1 publication Critical patent/FI101632B1/fi

1998-07-31 Publication of FI101632B publication Critical patent/FI101632B/fi

Links

OTLLEIBWKHEHGU-UHFFFAOYSA-N 2-[5-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-4-phosphonooxyhexanedioic acid Chemical compound C1=NC=2C(N)=NC=NC=2N1C(C(C1O)O)OC1COC1C(CO)OC(OC(C(O)C(OP(O)(O)=O)C(O)C(O)=O)C(O)=O)C(O)C1O OTLLEIBWKHEHGU-UHFFFAOYSA-N 0.000 abstract 1
241000588807 Bordetella Species 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
230000004071 biological effect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
231100000776 exotoxin Toxicity 0.000 abstract 1
239000002095 exotoxin Substances 0.000 abstract 1
230000002163 immunogen Effects 0.000 abstract 1
230000005847 immunogenicity Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000012986 modification Methods 0.000 abstract 1
230000004048 modification Effects 0.000 abstract 1
239000003053 toxin Substances 0.000 abstract 1
231100000765 toxin Toxicity 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

FI892131A 1987-09-04 1989-05-03 Menetelmä Bordetella pertussis-toksiinin alayksikön analogien valmista miseksi ja niitä koodaavia rekombinantti-DNA-molekyylejä FI101632B (fi)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US9430787A	1987-09-04	1987-09-04
US9430787		1987-09-04
US23248288A	1988-08-17	1988-08-17
US23248288		1988-08-17
US8802983		1988-08-26
PCT/US1988/002983 WO1989001976A1 (en)	1987-09-04	1988-08-26	Recombinant dna-derived bordetella toxin subunit analogs

Publications (4)

Publication Number	Publication Date
FI892131A FI892131A (fi)	1989-05-03
FI892131A0 true FI892131A0 (fi)	1989-05-03
FI101632B1 FI101632B1 (fi)	1998-07-31
FI101632B FI101632B (fi)	1998-07-31

Family

ID=26788722

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI892131A FI101632B (fi)	1987-09-04	1989-05-03	Menetelmä Bordetella pertussis-toksiinin alayksikön analogien valmista miseksi ja niitä koodaavia rekombinantti-DNA-molekyylejä

Country Status (16)

Country	Link
US (1)	US5773600A (fi)
EP (2)	EP0306318B2 (fi)
JP (1)	JP2918895B2 (fi)
KR (1)	KR0168039B1 (fi)
CN (1)	CN1033866C (fi)
AT (1)	ATE125568T1 (fi)
CA (1)	CA1341560C (fi)
DE (1)	DE3854213T3 (fi)
DK (1)	DK175821B1 (fi)
ES (1)	ES2076160T5 (fi)
FI (1)	FI101632B (fi)
GR (1)	GR3017497T3 (fi)
IE (1)	IE69753B1 (fi)
IL (3)	IL103121A (fi)
NO (2)	NO301844B1 (fi)
WO (1)	WO1989001976A1 (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6713072B1 (en) *	1987-11-02	2004-03-30	Chiron S.R.L.	Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
IT1223334B (it) *	1987-11-02	1990-09-19	Sclavo Spa	Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse
US5925546A (en) *	1987-11-02	1999-07-20	Chiron S.P.A.	Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine
US5358868A (en) *	1987-11-24	1994-10-25	Connaught Laboratories Limited	Genetic detoxification of pertussis toxin
GB8727489D0 (en) *	1987-11-24	1987-12-23	Connaught Lab	Detoxification of pertussis toxin
US5332583A (en) *	1987-11-24	1994-07-26	Connaught Laboratories Limited	Vaccine containing genetically-detoxified pertussis holotoxin
US7232671B2 (en) *	1989-02-15	2007-06-19	The United States Of America As Represented By The Secretary, Department Of Health And Human Services	Pertussis toxin gene: cloning and expression of protective antigen
CA2009991A1 (en) *	1989-02-15	1990-08-15	Witold Cieplak	Pertussis toxin gene: cloning and expression of protective antigen
ES2078258T3 (es) *	1989-04-28	1995-12-16	Sclavo Spa	Mutantes de toxina pertussica, cepas de bordetella capaces de producir tales mutantes y su uso en el desarrollo de vacunas antipertussicas.
US5786189A (en) *	1989-11-29	1998-07-28	Smithkline Beecham Biologicals (S.A.)	Vaccine
GB9326174D0 (en) *	1993-12-22	1994-02-23	Biocine Sclavo	Mucosal adjuvant
US20030072774A1 (en) *	1994-06-10	2003-04-17	Diane M. Gajewczyk	Proteinaceous adjuvants
CA2220063C (en) *	1995-05-04	2003-08-26	Connaught Laboratories Limited	Acellular pertussis vaccines and methods of preparation thereof
CA2253937A1 (en) *	1996-05-10	1997-11-20	Phylomed Corporation	Methods for oxidizing disulfide bonds using ozone
FR2754543B1 (fr)	1996-10-11	1998-12-31	Pasteur Institut	Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires
US6818222B1 (en)	1997-03-21	2004-11-16	Chiron Corporation	Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
US9453251B2 (en)	2002-10-08	2016-09-27	Pfenex Inc.	Expression of mammalian proteins in Pseudomonas fluorescens
GB0313916D0 (en)	2003-06-16	2003-07-23	Glaxosmithkline Biolog Sa	Vaccine composition
CA2574953A1 (en)	2004-07-26	2006-02-09	Dow Global Technolgies Inc.	Process for improved protein expression by strain engineering
US8048433B2 (en) *	2004-12-17	2011-11-01	Nvi Nederlands Vaccininstituut	Deacylation of LPS in gram negative bacteria
JP5444553B2 (ja)	2007-04-27	2014-03-19	フェネックスインコーポレイテッド	微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法
US9580719B2 (en)	2007-04-27	2017-02-28	Pfenex, Inc.	Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
ITMI20090946A1 (it)	2009-05-28	2010-11-29	Novartis Ag	Espressione di proteine ricombinanti
BR112012024898A2 (pt)	2010-03-30	2015-10-06	Pfenex Inc	expressão de nível elevado de proteínas recombinantes de toxinas
US9169304B2 (en)	2012-05-01	2015-10-27	Pfenex Inc.	Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
US20140037680A1 (en)	2012-08-06	2014-02-06	Glaxosmithkline Biologicals, S.A.	Novel method
SG11201500573RA (en)	2012-08-06	2015-02-27	Glaxosmithkline Biolog Sa	Method for eliciting in infants an immune response against rsv and b. pertussis
PE20151720A1 (es)	2013-03-08	2015-12-10	Crucell Holland Bv	Vacuna acelular contra pertussis
EP3030260A1 (en)	2013-08-05	2016-06-15	GlaxoSmithKline Biologicals S.A.	Combination immunogenic compositions
CN109172818B (zh) *	2018-08-02	2021-10-22	浙江康佰裕生物科技有限公司	一种蛋白牛痘疫苗及其效力检测方法
CA3115085A1 (en) *	2018-10-15	2020-04-23	Arizona Board Of Regents On Behalf Of The University Of Arizona	Vaccine polypeptide compositions and methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4704362A (en) *	1977-11-08	1987-11-03	Genentech, Inc.	Recombinant cloning vehicle microbial polypeptide expression
FR2590483B1 (fr) *	1985-11-22	1988-12-09	Pasteur Institut	Antigenes purifies ayant des proprietes vaccinantes contre b. pertussis, moyens notamment adns recombinants pour les produire et compositions de vaccins les contenant
CA1340373C (en) *	1986-01-28	1999-02-02	Rino Rappuoli	Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin
ATE80179T1 (de) *	1986-12-23	1992-09-15	Univ Leland Stanford Junior	Modifiziertes pertussistoxin.
IT1223334B (it) *	1987-11-02	1990-09-19	Sclavo Spa	Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse
GB8727489D0 (en) *	1987-11-24	1987-12-23	Connaught Lab	Detoxification of pertussis toxin
IT1223529B (it) *	1987-12-18	1990-09-19	Sclavo Spa	Epitopo immunodominante protettivo contenuto nella subunita' s1 della tossina della pertosse

1988
- 1988-08-26 JP JP63507460A patent/JP2918895B2/ja not_active Expired - Lifetime
- 1988-08-26 WO PCT/US1988/002983 patent/WO1989001976A1/en active IP Right Grant
- 1988-08-26 KR KR1019890700803A patent/KR0168039B1/ko not_active IP Right Cessation
- 1988-08-30 IL IL10312188A patent/IL103121A/en not_active IP Right Cessation
- 1988-08-30 IL IL87608A patent/IL87608A0/xx not_active IP Right Cessation
- 1988-09-01 EP EP88308124A patent/EP0306318B2/en not_active Expired - Lifetime
- 1988-09-01 AT AT88308124T patent/ATE125568T1/de not_active IP Right Cessation
- 1988-09-01 EP EP94109317A patent/EP0629696A1/en not_active Withdrawn
- 1988-09-01 DE DE3854213T patent/DE3854213T3/de not_active Expired - Lifetime
- 1988-09-01 ES ES88308124T patent/ES2076160T5/es not_active Expired - Lifetime
- 1988-09-02 CA CA 576469 patent/CA1341560C/en not_active Expired - Fee Related
- 1988-09-02 IE IE266888A patent/IE69753B1/en not_active IP Right Cessation
- 1988-09-05 CN CN88107056A patent/CN1033866C/zh not_active Expired - Lifetime
1989
- 1989-05-03 FI FI892131A patent/FI101632B/fi not_active IP Right Cessation
- 1989-05-03 DK DK198902162A patent/DK175821B1/da active
- 1989-05-03 NO NO891842A patent/NO301844B1/no not_active IP Right Cessation
1992
- 1992-09-09 IL IL103121A patent/IL103121A0/xx unknown
1995
- 1995-06-06 US US08/468,679 patent/US5773600A/en not_active Expired - Lifetime
- 1995-09-21 GR GR950402614T patent/GR3017497T3/el unknown
1997
- 1997-06-09 NO NO19972642A patent/NO325016B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0629696A1 (en)	1994-12-21
NO301844B1 (no)	1997-12-15
US5773600A (en)	1998-06-30
NO972642D0 (no)	1997-06-09
ATE125568T1 (de)	1995-08-15
FI101632B1 (fi)	1998-07-31
KR0168039B1 (ko)	1999-01-15
DK175821B1 (da)	2005-03-14
AU2386488A (en)	1989-03-31
FI892131A (fi)	1989-05-03
IE69753B1 (en)	1996-10-02
EP0306318B2 (en)	2004-04-28
DE3854213D1 (de)	1995-08-31
GR3017497T3 (en)	1995-12-31
CN1033866C (zh)	1997-01-22
ES2076160T3 (es)	1995-11-01
JPH04501051A (ja)	1992-02-27
NO891842D0 (no)	1989-05-03
KR890701758A (ko)	1989-12-21
IL103121A0 (en)	1993-02-21
ES2076160T5 (es)	2004-12-01
IL103121A (en)	1995-08-31
NO891842L (no)	1989-06-21
IL87608A0 (en)	1989-01-31
NO972642L (no)	1997-07-28
IE882668L (en)	1989-03-04
CA1341560C (en)	2007-10-30
CN1033072A (zh)	1989-05-24
WO1989001976A1 (en)	1989-03-09
FI101632B (fi)	1998-07-31
DK216289A (da)	1989-06-30
AU623867B2 (en)	1992-05-28
EP0306318A1 (en)	1989-03-08
DE3854213T2 (de)	1995-12-07
EP0306318B1 (en)	1995-07-26
DK216289D0 (da)	1989-05-03
NO325016B1 (no)	2008-01-14
DE3854213T3 (de)	2004-10-21
JP2918895B2 (ja)	1999-07-12

Legal Events

Date	Code	Title	Description
2004-08-31	FG	Patent granted	Owner name: AMGEN INC.
2008-09-19	MA	Patent expired

Publication	Publication Date	Title
FI892131A (fi)	1989-05-03	Analoger till underenheter av bordetellatoxin, vilka haerstammar fraon hybrid-dna.
MX9203458A (es)	1992-09-01	Segmentos inmunogenicos que contienen glicoproteinas quimericas de las glicoproteinas de virus sincitial respiratorio humano.
PT625053E (pt)	2002-09-30	Vacina a base de urease contra a infeccao por helicobacter
ATE181572T1 (de)	1999-07-15	Ospa proteine von borrelia burgdorferi untergruppen, dafür kodierende gene sowie impfstoffe
KR970009347B1 (en)	1997-06-10	Chimeric glycoproteins containing immunogenic segments of human parainfluenza virus type 3
LU91153I2 (fr)	2005-06-23	Combinaison d'anatoxine diphtérique, d'anatoxine tétanique, d'anatoxine coquelucheuse, d'hémagglutinine filamenteuse, de pertactine et de polyoside capsulaire d'Haemophilus influenzae type b.
ATE157258T1 (de)	1997-09-15	Zubereitungen und behandlungen von pneumonia in tieren
DE69510858D1 (de)	1999-08-26	Mukosale Verabreichung von Pneumokokken-Antigenen
DK0563254T3 (da)	1996-02-12	Anvendelse af IL-4 til forstærkning af immunrespons på immunogener i vacciner
DE69130206D1 (de)	1998-10-22	Impfstoff aus reassortiertem rotavirus
EP0636030A4 (en)	1996-02-07	VACCINE AGAINST THE -I BACTERIAL OXIDE (PASTEURELLIA HAEMOLYTICA).
DK230890A (da)	1990-09-24	Dna-fragment, der koder for et pasteurella multocida-toxin eller for en subsekvens eller analog deraf, ekspressionsvektor, der omfatter dna-fragmentet, mikroorganisme, der udtrykker dette, fremgangsmaade til fremstilling af et pasteurella-multocida-toxin, diagnostisk middel samt anvendelse heraf, vaccine indeholdende et pasteurella-multocida-toxinderivat, anvendelse af pasteurella multocida-t m.m.