FI841181A - Nya n-fenyl-n'-cykloalkylalkanoy- piperaziner och foerfarande foer deras framstaellning. - Google Patents
Nya n-fenyl-n'-cykloalkylalkanoy- piperaziner och foerfarande foer deras framstaellning. Download PDFInfo
- Publication number
- FI841181A FI841181A FI841181A FI841181A FI841181A FI 841181 A FI841181 A FI 841181A FI 841181 A FI841181 A FI 841181A FI 841181 A FI841181 A FI 841181A FI 841181 A FI841181 A FI 841181A
- Authority
- FI
- Finland
- Prior art keywords
- groups
- radical
- phenyl
- piperaziner
- cycloalkylalkanoy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3310871 | 1983-03-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI841181A0 FI841181A0 (fi) | 1984-03-23 |
| FI841181A true FI841181A (fi) | 1984-09-26 |
Family
ID=6194617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI841181A FI841181A (fi) | 1983-03-25 | 1984-03-23 | Nya n-fenyl-n'-cykloalkylalkanoy- piperaziner och foerfarande foer deras framstaellning. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4547505A (fi) |
| EP (1) | EP0120465B1 (fi) |
| JP (1) | JPS59205362A (fi) |
| AT (1) | ATE20887T1 (fi) |
| AU (1) | AU560579B2 (fi) |
| CA (1) | CA1211435A (fi) |
| DD (1) | DD213215A5 (fi) |
| DE (1) | DE3460325D1 (fi) |
| DK (1) | DK142084A (fi) |
| ES (2) | ES8501384A1 (fi) |
| FI (1) | FI841181A (fi) |
| HU (1) | HU191643B (fi) |
| IL (1) | IL71324A (fi) |
| NO (1) | NO841163L (fi) |
| PT (1) | PT78304B (fi) |
| SU (1) | SU1297727A3 (fi) |
| ZA (1) | ZA842185B (fi) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2536071B1 (fr) * | 1982-11-12 | 1986-07-11 | Sanofi Sa | Sels acides de 2-piperazinopyrimidine, procede pour leur preparation et compositions pharmaceutiques en contenant |
| EP0582065A1 (en) * | 1986-08-15 | 1994-02-09 | WHITBY RESEARCH, Inc. | 1-Oxohydrocarbyl-substituted azacyclohexanes compositions used as acid catalyst |
| US4797405A (en) * | 1987-10-26 | 1989-01-10 | Eli Lilly And Company | Stabilized pergolide compositions |
| DE68912282T2 (de) * | 1988-11-24 | 1994-04-28 | Akzo Nv | 1-[Mono- oder bis(trifluormethyl)-2-pyridinyl]piperazine enthaltende pharmazeutische Zusammensetzungen. |
| EP0385043A1 (en) * | 1989-02-28 | 1990-09-05 | Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. (Faes) | New derivatives of 4-substituted piperazines |
| US5648352A (en) * | 1991-09-13 | 1997-07-15 | Merck & Co., Inc. | Piperazinylcamphorsulfonyl oxytocin antagonists |
| EP0533242A3 (en) * | 1991-09-16 | 1993-09-15 | Merck & Co. Inc. | Substituted derivatives of piperazinylcamphorsulfonyl oxytocin antagonists |
| EP0533240A3 (en) * | 1991-09-16 | 1993-09-29 | Merck & Co. Inc. | Substituted amine derivatives of piperazinylcamphorsulfonyl oxytocin antagonists |
| EP0533241A3 (en) * | 1991-09-16 | 1993-09-29 | Merck & Co. Inc. | Substituted alkyl derivatives of piperazinylcamphorsulfonyl oxytocin antagonists |
| JPH05255089A (ja) * | 1991-12-18 | 1993-10-05 | Sanwa Kagaku Kenkyusho Co Ltd | 抗ウイルス剤 |
| HU209678B (en) * | 1992-06-09 | 1994-10-28 | Richter Gedeon Vegyeszet | Process for producing biologically active eburnamenin-14-carbonyl-amino derivatives and pharmaceutical compositions containing them |
| AU675730B2 (en) * | 1993-07-16 | 1997-02-13 | Merck & Co., Inc. | Substituted piperazinylcamphor derivatives as oxytocin antagonists |
| ES2125206B1 (es) * | 1997-07-21 | 1999-11-16 | Esteve Labor Dr | Derivados de acil-piperazinil-pirimidinas, su preparacion y su aplicacion como medicamentos. |
| ES2167276B1 (es) * | 2000-10-20 | 2003-04-01 | Esteve Labor Dr | Nuevos derivados de cianoaril (o cianoheteroaril)-carbonil-piperazinil-pirimidinas, su preparacion y su aplicacion como medicamentos. |
| US20050256130A1 (en) * | 2002-06-12 | 2005-11-17 | Chemocentryx, Inc. | Substituted piperazines |
| AU2003236500B9 (en) | 2002-06-12 | 2009-07-02 | Chemocentryx, Inc. | 1-aryl-4-substituted piperazine derivatives for use as CCR1 antagonists for the treatment of inflammation and immune disorders |
| US7589199B2 (en) * | 2002-06-12 | 2009-09-15 | Chemocentryx, Inc. | Substituted piperazines |
| US7842693B2 (en) * | 2002-06-12 | 2010-11-30 | Chemocentryx, Inc. | Substituted piperazines |
| JP4960085B2 (ja) * | 2003-03-19 | 2012-06-27 | エクセリクシス， インク． | Ｔｉｅ−２モジュレータと使用方法 |
| US7435831B2 (en) * | 2004-03-03 | 2008-10-14 | Chemocentryx, Inc. | Bicyclic and bridged nitrogen heterocycles |
| JP4845873B2 (ja) * | 2004-03-03 | 2011-12-28 | ケモセントリックス インコーポレーティッド | 二環式および架橋した窒素複素環 |
| US8389510B2 (en) * | 2005-11-18 | 2013-03-05 | Astrazeneca Ab | Crystalline forms |
| WO2008079838A1 (en) * | 2006-12-20 | 2008-07-03 | Astrazeneca Ab | Compounds and uses thereof |
| CN101835750B (zh) * | 2007-08-22 | 2013-07-17 | 阿斯利康(瑞典)有限公司 | 环丙基酰胺衍生物 |
| TW201039825A (en) * | 2009-02-20 | 2010-11-16 | Astrazeneca Ab | Cyclopropyl amide derivatives 983 |
| BR112012020629A2 (pt) | 2010-02-18 | 2018-06-19 | Astrazeneca Ab | forma cristalina, e, método para a terapia de um distúrbio |
| BR112012020780A2 (pt) * | 2010-02-18 | 2016-05-03 | Astrazeneca Ab | forma sólida, composição farmacêutica, e, uso de uma forma sólida. |
| FR3000065A1 (fr) | 2012-12-21 | 2014-06-27 | Univ Lille Ii Droit & Sante | Composes bicycliques ayant une activite potentialisatrice de l'activite d'un antibiotique actif contre les mycobacteries-composition et produit pharmaceutiques comprenant de tels composes |
| CN115368318B (zh) * | 2022-06-22 | 2023-11-03 | 山东辰龙药业有限公司 | 一种伏硫西汀的合成方法及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK143899C (da) * | 1975-04-21 | 1982-04-13 | Merck & Co Inc | Analogifremgangsmaade til fremstilling af piperazinylpyrazinderivater |
| JPS52286A (en) * | 1975-05-27 | 1977-01-05 | Kyorin Pharmaceut Co Ltd | Method of preparing 1-(3-phenylpropyl)-4-acylpiperazine derivatives |
| GB1534593A (en) * | 1976-09-03 | 1978-12-06 | Soc D Etudes Prod Chimique | N-2,6-dichlorophenyl-2-aminopyrimidine and therapeutic compositions containing it |
| AU546260B2 (en) * | 1980-06-16 | 1985-08-22 | Ferrosan A.B. | Diphenylbutyl-1-acylpiperazines |
| US4666911A (en) * | 1981-07-14 | 1987-05-19 | Taiho Pharmaceutical Company Limited | Allophanoylpiperazine compound and analgesic composition containing same as active ingredient |
| JPS591474A (ja) * | 1982-06-07 | 1984-01-06 | Nippon Iyakuhin Kogyo Kk | ピペラジン環を有するゲラニルゲラニル酢酸アミド化合物またはその塩類 |
-
1984
- 1984-02-24 US US06/583,324 patent/US4547505A/en not_active Expired - Fee Related
- 1984-02-29 DK DK142084A patent/DK142084A/da not_active Application Discontinuation
- 1984-03-21 JP JP59052465A patent/JPS59205362A/ja active Pending
- 1984-03-22 DD DD84261152A patent/DD213215A5/de unknown
- 1984-03-22 AT AT84103136T patent/ATE20887T1/de not_active IP Right Cessation
- 1984-03-22 DE DE8484103136T patent/DE3460325D1/de not_active Expired
- 1984-03-22 EP EP84103136A patent/EP0120465B1/de not_active Expired
- 1984-03-23 PT PT78304A patent/PT78304B/pt unknown
- 1984-03-23 ES ES530902A patent/ES8501384A1/es not_active Expired
- 1984-03-23 HU HU841168A patent/HU191643B/hu unknown
- 1984-03-23 ES ES530901A patent/ES530901A0/es active Granted
- 1984-03-23 CA CA000450313A patent/CA1211435A/en not_active Expired
- 1984-03-23 FI FI841181A patent/FI841181A/fi not_active Application Discontinuation
- 1984-03-23 NO NO841163A patent/NO841163L/no unknown
- 1984-03-23 IL IL71324A patent/IL71324A/xx not_active IP Right Cessation
- 1984-03-23 AU AU26057/84A patent/AU560579B2/en not_active Ceased
- 1984-03-23 ZA ZA842185A patent/ZA842185B/xx unknown
- 1984-03-23 SU SU843713674A patent/SU1297727A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| US4547505A (en) | 1985-10-15 |
| PT78304A (de) | 1984-04-01 |
| ES530902A0 (es) | 1984-11-16 |
| CA1211435A (en) | 1986-09-16 |
| ES8501383A1 (es) | 1984-11-16 |
| PT78304B (de) | 1986-04-22 |
| ATE20887T1 (de) | 1986-08-15 |
| ES8501384A1 (es) | 1984-11-16 |
| AU2605784A (en) | 1984-09-27 |
| EP0120465B1 (de) | 1986-07-23 |
| FI841181A0 (fi) | 1984-03-23 |
| DD213215A5 (de) | 1984-09-05 |
| IL71324A (en) | 1987-08-31 |
| DK142084D0 (da) | 1984-02-29 |
| EP0120465A1 (de) | 1984-10-03 |
| ES530901A0 (es) | 1984-11-16 |
| NO841163L (no) | 1984-09-26 |
| IL71324A0 (en) | 1984-06-29 |
| HU191643B (en) | 1987-03-30 |
| AU560579B2 (en) | 1987-04-09 |
| JPS59205362A (ja) | 1984-11-20 |
| ZA842185B (en) | 1984-10-31 |
| SU1297727A3 (ru) | 1987-03-15 |
| DK142084A (da) | 1984-09-26 |
| DE3460325D1 (en) | 1986-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |
Owner name: DEGUSSA AKTIENGESELLSCHAFT |