FI70571B - Azetidinonderivat anvaendbara som mellanprodukt vid framstaellning av 1-oxadetiacefalosporiner - Google Patents
Azetidinonderivat anvaendbara som mellanprodukt vid framstaellning av 1-oxadetiacefalosporiner Download PDFInfo
- Publication number
- FI70571B FI70571B FI780382A FI780382A FI70571B FI 70571 B FI70571 B FI 70571B FI 780382 A FI780382 A FI 780382A FI 780382 A FI780382 A FI 780382A FI 70571 B FI70571 B FI 70571B
- Authority
- FI
- Finland
- Prior art keywords
- cob
- compound
- mixture
- r1conh
- oxadetiacefalosporiner
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
Claims (3)
1. Azetidinonderivat användbara som mellanprodukt vid framsta]l-ning av 1-oxadetiacefalosporiner kännetecknade av forme In R1C0NH OCHdR2 R1CONH °CHpR V e]]er "rS o>nhc o*Kc=c^3 / CH3 (lb) (la) COB ^ (lb) vari R1 betecknar metyl, bensyl, fenoximetyl eller fenyl; R betecknar vinyl, etynyl, 2-bromoetyny1, acetoxiacety1, (l-metyltetrazol-R-yl)-tioacety1, 1-metylen-2-acetoxietyl eller 1-metoxikarbonylmetylen-2-(l-metyltetrazol-5-yl)tioetyl; och COB betecknar bensyloxi-karbonyl, difenylmetoxikarbony1 eller t-butoxikarbony1.
2. Förening enligt krav 1, kännetecknad av att R^ betecknar bensyl eller fenyl; R betecknar vinyl eller etynyl; och COB betecknar difenylmetoxikarbony1.
3. Förfarande för framställning av azetidinonderivat enligt krav 1 med formeln 2 R1CONH OCH-R2 R1CONH OCI^R β11θΓ β 0>\ ^CH2 0^ \ yCH 0 nhc-c' * \=C 3 / ^CH, / \;h7 (Ia) COB 3 (Ib) COB 3 vari R1 betecknar metyl, bensyl, fenoximetyl eller fenyl; R betecknar vinyl, etynyl, 2-bromoetynyl, acetoxiacety1, (1-metyltetrazol-5-yl)“ tioacetyl, l-metylen-2-acetoxietyl eller l-metoxikarbonylmetylen-2-(1-metyltetrazol-5-y1)tioetyl; och COB betecknar bensyloxi-karbonyl, difenylmetoxikarbony1 eller t-butoxikarbony1, k ä n-
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1345277A JPS5398951A (en) | 1977-02-08 | 1977-02-08 | Azetidinone derivatives and process for their preparation |
JP1345277 | 1977-02-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI780382A FI780382A (fi) | 1978-08-09 |
FI70571B true FI70571B (fi) | 1986-06-06 |
FI70571C FI70571C (fi) | 1986-09-24 |
Family
ID=11833524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI780382A FI70571C (fi) | 1977-02-08 | 1978-02-07 | Azetidinonderivat anvaendbara som mellanprodukt vid framstaellning av 1-oxadetiacefalosporiner |
Country Status (32)
Country | Link |
---|---|
US (1) | US4233216A (sv) |
JP (1) | JPS5398951A (sv) |
AR (1) | AR220700A1 (sv) |
AT (1) | AT357551B (sv) |
AU (1) | AU515901B2 (sv) |
BE (1) | BE863700A (sv) |
BG (1) | BG31947A3 (sv) |
CA (1) | CA1111856A (sv) |
CH (1) | CH637637A5 (sv) |
CS (1) | CS200539B2 (sv) |
DD (1) | DD134764A5 (sv) |
DE (1) | DE2805222A1 (sv) |
DK (1) | DK54678A (sv) |
ES (1) | ES466741A1 (sv) |
FI (1) | FI70571C (sv) |
FR (1) | FR2379521A1 (sv) |
GB (1) | GB1561704A (sv) |
GR (1) | GR70055B (sv) |
HU (1) | HU177509B (sv) |
IE (1) | IE46389B1 (sv) |
IL (1) | IL53984A (sv) |
NL (1) | NL7801350A (sv) |
NO (1) | NO149352C (sv) |
NZ (1) | NZ186400A (sv) |
PH (1) | PH14953A (sv) |
PL (1) | PL111962B1 (sv) |
PT (1) | PT67617B (sv) |
RO (1) | RO73274A (sv) |
SE (1) | SE437826B (sv) |
SU (1) | SU869558A3 (sv) |
YU (1) | YU41306B (sv) |
ZA (1) | ZA78726B (sv) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4443598A (en) * | 1977-02-15 | 1984-04-17 | Shionogi & Co., Ltd. | 1-Oxadethiacepham compounds |
US4533730A (en) * | 1977-02-15 | 1985-08-06 | Shionogi & Co., Ltd. | 1-Oxadethiacepham compounds |
AU514377B2 (en) * | 1977-02-15 | 1981-02-05 | Shionogi & Co., Ltd. | l-OXADETHIACEPHAM COMPOUNDS |
JPS55133355A (en) * | 1979-04-03 | 1980-10-17 | Shionogi & Co Ltd | Inversion of 3-amino group of beta-lactam ring |
US4243588A (en) * | 1979-06-19 | 1981-01-06 | Eli Lilly And Company | Process for novel oxazolinoazetidinones |
JPS5936684A (ja) * | 1982-08-24 | 1984-02-28 | Shionogi & Co Ltd | 1−オキサセフアム化合物の製造方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL178005C (nl) | 1972-11-06 | 1986-01-02 | Merck & Co Inc | Werkwijze voor het bereiden van een farmaceutisch preparaat met antibacteriele werking, alsmede werkwijze ter bereiding van een cefalosporine-antibioticum. |
GB1505345A (en) * | 1974-04-10 | 1978-03-30 | Beecham Group Ltd | Cephalosporins |
GB1552122A (en) | 1975-05-10 | 1979-09-05 | Beecham Group Ltd | 1-oxa-1-dethia-ceph-3-em-4-carboxylic acid derivatives preparation and compositions |
US4143038A (en) * | 1975-11-12 | 1979-03-06 | Shionogi & Co., Ltd. | Cephalosporin analogues |
US4070477A (en) * | 1975-12-08 | 1978-01-24 | Ciba-Geigy Corporation | 2-Penem compounds |
IT1058858B (it) * | 1976-02-23 | 1982-05-10 | Snam Progetti | 5.6 deidropenicilline processo per la loro preparazione e intermdi ottenibili in detto processo |
JPS607635B2 (ja) * | 1976-04-27 | 1985-02-26 | 塩野義製薬株式会社 | オキサゾリジン化合物 |
-
1977
- 1977-02-08 JP JP1345277A patent/JPS5398951A/ja active Granted
-
1978
- 1978-01-21 GR GR55229A patent/GR70055B/el unknown
- 1978-02-02 IE IE221/78A patent/IE46389B1/en not_active IP Right Cessation
- 1978-02-03 CA CA296,262A patent/CA1111856A/en not_active Expired
- 1978-02-04 PT PT67617A patent/PT67617B/pt unknown
- 1978-02-06 CS CS78761A patent/CS200539B2/cs unknown
- 1978-02-06 NL NL7801350A patent/NL7801350A/xx not_active Application Discontinuation
- 1978-02-06 SE SE7801352A patent/SE437826B/sv not_active IP Right Cessation
- 1978-02-06 IL IL53984A patent/IL53984A/xx unknown
- 1978-02-06 AU AU33045/78A patent/AU515901B2/en not_active Expired
- 1978-02-06 BE BE184947A patent/BE863700A/xx not_active IP Right Cessation
- 1978-02-06 NO NO780414A patent/NO149352C/no unknown
- 1978-02-06 DK DK54678A patent/DK54678A/da not_active Application Discontinuation
- 1978-02-06 GB GB4734/78A patent/GB1561704A/en not_active Expired
- 1978-02-07 PH PH20759A patent/PH14953A/en unknown
- 1978-02-07 FR FR7803443A patent/FR2379521A1/fr active Granted
- 1978-02-07 ES ES466741A patent/ES466741A1/es not_active Expired
- 1978-02-07 HU HU78SI1615A patent/HU177509B/hu unknown
- 1978-02-07 DD DD78203592A patent/DD134764A5/xx unknown
- 1978-02-07 NZ NZ186400A patent/NZ186400A/xx unknown
- 1978-02-07 CH CH134978A patent/CH637637A5/de not_active IP Right Cessation
- 1978-02-07 FI FI780382A patent/FI70571C/fi not_active IP Right Cessation
- 1978-02-07 ZA ZA00780726A patent/ZA78726B/xx unknown
- 1978-02-07 AT AT84378A patent/AT357551B/de not_active IP Right Cessation
- 1978-02-08 DE DE19782805222 patent/DE2805222A1/de not_active Ceased
- 1978-02-08 YU YU293/78A patent/YU41306B/xx unknown
- 1978-02-08 BG BG038617A patent/BG31947A3/xx unknown
- 1978-02-08 SU SU782577000A patent/SU869558A3/ru active
- 1978-02-08 RO RO7893148A patent/RO73274A/ro unknown
- 1978-02-08 PL PL1978204672A patent/PL111962B1/pl unknown
- 1978-02-08 AR AR271028A patent/AR220700A1/es active
- 1978-12-06 US US05/967,007 patent/US4233216A/en not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MA | Patent expired | ||
MA | Patent expired |
Owner name: SHIONOGI & CO, LTD |