FI61189C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d-6-alkyl-8-cyanmetylergoliner-i och deras salt - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d-6-alkyl-8-cyanmetylergoliner-i och deras salt Download PDF

Info

Publication number
FI61189C
FI61189C FI763442A FI763442A FI61189C FI 61189 C FI61189 C FI 61189C FI 763442 A FI763442 A FI 763442A FI 763442 A FI763442 A FI 763442A FI 61189 C FI61189 C FI 61189C
Authority
FI
Finland
Prior art keywords
formula
cyanomethylergoline
alkyl
mmol
iii
Prior art date
Application number
FI763442A
Other languages
English (en)
Finnish (fi)
Other versions
FI763442A (de
FI61189B (fi
Inventor
Antonin Cerny
Miroslav Semonsky
Rudolf Kotva
Karel Rezabek
Marie Auskova
Miroslav Seda
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of FI763442A publication Critical patent/FI763442A/fi
Publication of FI61189B publication Critical patent/FI61189B/fi
Application granted granted Critical
Publication of FI61189C publication Critical patent/FI61189C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI763442A 1975-12-12 1976-11-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d-6-alkyl-8-cyanmetylergoliner-i och deras salt FI61189C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CS758472A CS188414B1 (en) 1975-12-12 1975-12-12 New d-6-alkyl-8-cyanmethyl ergolines,their salts and method of producing
CS847275 1975-12-12

Publications (3)

Publication Number Publication Date
FI763442A FI763442A (de) 1977-06-13
FI61189B FI61189B (fi) 1982-02-26
FI61189C true FI61189C (fi) 1982-06-10

Family

ID=5435273

Family Applications (1)

Application Number Title Priority Date Filing Date
FI763442A FI61189C (fi) 1975-12-12 1976-11-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d-6-alkyl-8-cyanmetylergoliner-i och deras salt

Country Status (15)

Country Link
US (1) US4321380A (de)
JP (1) JPS5285195A (de)
AT (1) AT356293B (de)
AU (1) AU502928B2 (de)
BE (1) BE849318A (de)
CA (1) CA1069502A (de)
CH (1) CH622259A5 (de)
CS (1) CS188414B1 (de)
DE (1) DE2656093A1 (de)
DK (1) DK141874B (de)
FI (1) FI61189C (de)
FR (1) FR2334360A1 (de)
GB (1) GB1505800A (de)
NL (1) NL7613843A (de)
SE (1) SE419986B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3913756A1 (de) * 1989-04-21 1990-10-25 Schering Ag 8(beta)-substituierte ergoline, verfahren zu ihrer herstellung und ihre verwendung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE712054A (de) * 1967-03-16 1968-07-15
US3920664A (en) * 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
US3880856A (en) * 1973-06-29 1975-04-29 Lilly Co Eli Ergoline dimers
CS171480B1 (de) * 1974-03-19 1976-10-29
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
US3992385A (en) * 1975-01-20 1976-11-16 Eli Lilly And Company 2,3-Dihydroergolines

Also Published As

Publication number Publication date
AT356293B (de) 1980-04-25
FI763442A (de) 1977-06-13
BE849318A (fr) 1977-04-01
US4321380A (en) 1982-03-23
CS188414B1 (en) 1979-03-30
FI61189B (fi) 1982-02-26
FR2334360B1 (de) 1980-03-07
CH622259A5 (de) 1981-03-31
SE419986B (sv) 1981-09-07
JPS5285195A (en) 1977-07-15
ATA881776A (de) 1979-09-15
DE2656093A1 (de) 1977-06-23
AU2037776A (en) 1978-06-15
DK141874B (da) 1980-07-07
AU502928B2 (en) 1979-08-16
FR2334360A1 (fr) 1977-07-08
NL7613843A (nl) 1977-06-14
GB1505800A (en) 1978-03-30
SE7613673L (sv) 1977-06-13
CA1069502A (en) 1980-01-08
DK553376A (de) 1977-06-13
DK141874C (de) 1980-12-15

Similar Documents

Publication Publication Date Title
Turner et al. Studies on imidazole compounds. I. 4-Methylimidazole and related compounds
US5817879A (en) Alicyclic peptidomimetics
DE3688559T2 (de) Zwischenprodukte in der synthese von diaminandrostan-derivaten.
DK144160B (da) Analogifremgangsmaade til fremstilling af 8-thiomethylergoliner
SU1549485A3 (ru) Способ получени производных 6-метиленандроста-1,4-диен-3,17-диона
DE69126978T2 (de) Derivate des 6-amino-octahydro-indolizintriols
DE2333847A1 (de) Tetrahydronaphthole, ihre salze und diese verbindungen enthaltende arzneimittel
FI61189C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara d-6-alkyl-8-cyanmetylergoliner-i och deras salt
EP0081726A1 (de) Amidderivate von Nitrobenzoesäuren
JPS58180484A (ja) 1−置換N−/8α−エルゴリニル/−N′,N′−ジエチルウレア及びその製造方法
DE69228307T2 (de) Imidazo(1,2-c)chinazolinderivate als antihypertensive und antidysurie
Cannon et al. 6-Hydroxy-4-[2-di-n-propylaminoethyl] indole: synthesis and dopaminergic actions
US5250564A (en) Aromatic peptidomimetics
KR880001320B1 (ko) 2-시클릭아미노-2-(1, 2-벤지속사졸-3-일)아세트산 에스테르 유도체들의 제조방법
EP0680960A1 (de) Imidazolverbindung
DE3336225A1 (de) Verfahren zur herstellung von imidazolen und neue zwischenprodukte fuer die verwendung in diesem verfahren
Pitha et al. Affinity labels for. beta.-adrenoceptors: preparation and properties of alkylating. beta.-blockers derived from indole
DD258006A5 (de) Verfahren zur herstellung von hydrozon-derivaten
DE3689321T2 (de) Hydroxyalkoxy-4-phenylpropylindolderivate, ihre Salze, Verfahren und Zwischenprodukte zur Herstellung, Anwendung als Heilmittel und Zusammensetzungen die sie enthalten.
NO883263L (no) Fremgangsmaate for fremstilling av terapeutisk aktive benzimidazol-derivater.
US4223146A (en) 4,5,6,7-Tetrahydroimidazo-[4,5-c]-pyridine derivatives
PL162513B1 (pl) Sposób wytwarzania nowych pochodnych i midazolu PL PL PL PL PL
EP0338877A1 (de) Verbindungen zur selektiven Bindung von s-hydroxytryptamine 1-A-rezeptoren und sie enthaltenden Arzneimittelzusammensetzungen
EP0101633B1 (de) Pyridincarboxylsäureester von Dopamin und seinen N-Alkyl-Derivaten
EP0029117B1 (de) 10-Bromsandwicin und 10-Bromisosandwicin sowie deren Säureadditionssalze mit pharmakoloyisch annehmbaren Säuren, Verfahren zu deren Herstellung und deren Verwendung

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SPOFA SPOJENé PODNIKY PRO ZDRAVOTNICKOU