FI53969C - Saosom utgaongsaemne vid framstaellning av terapeutiskt vaerdefulla 2 4-diamino-5-bensylpyrimidiner anvaendbar n-substituerad beta-amino-alfa-bensylakrylnitril vilken aer vaesentligen fri fraon foeroreningar foerorsakade av beta-amino-alfa-bensylidenpropionitril-isomeren och foerfarande foer dess framstaellning - Google Patents
Saosom utgaongsaemne vid framstaellning av terapeutiskt vaerdefulla 2 4-diamino-5-bensylpyrimidiner anvaendbar n-substituerad beta-amino-alfa-bensylakrylnitril vilken aer vaesentligen fri fraon foeroreningar foerorsakade av beta-amino-alfa-bensylidenpropionitril-isomeren och foerfarande foer dess framstaellningInfo
- Publication number
- FI53969C FI53969C FI587/70A FI58770A FI53969C FI 53969 C FI53969 C FI 53969C FI 587/70 A FI587/70 A FI 587/70A FI 58770 A FI58770 A FI 58770A FI 53969 C FI53969 C FI 53969C
- Authority
- FI
- Finland
- Prior art keywords
- beta
- alpha
- amino
- framstaellning
- væsentlig
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Steroid Compounds (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI297673A FI55495C (fi) | 1969-05-16 | 1973-09-25 | Foerfarande foer framstaellning av alfa-bensylakrylonitrilderivat vilka aer vaesentligen fria fraon foeroreningar foerorsakade av beta-amino-alfa-bensylidenpropionitril-isomerer |
FI298073A FI59403C (fi) | 1969-03-06 | 1973-09-25 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 2,4-diamino-5-bensylpyrimidiner |
FI297773A FI55496C (fi) | 1969-03-06 | 1973-09-25 | Foerfarande foer framstaellning av beta-anilino-alfa-bensylakrylonitrilderivat |
FI297973A FI55180C (fi) | 1969-03-06 | 1973-09-25 | Foerfarande foer framstaellning av alfa-bensylakrylonitrilderivat |
FI297873A FI55197C (fi) | 1969-03-06 | 1973-09-25 | Foerfarande foer framstaellning av beta-morfolino-alfa-3 4 5-trimetoxibensylakrylonitril |
FI771479A FI66594C (fi) | 1969-03-06 | 1977-05-10 | Foerfarande foer framstaellning av beta-anilino-alfa-benzylakrylonitriler |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1190969 | 1969-03-06 | ||
GB30247/69A GB1261455A (en) | 1969-03-06 | 1969-03-06 | Improvements in or relating to substituted acrylonitriles |
GB2517169 | 1969-05-16 | ||
GB3024769 | 1969-06-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI53969B FI53969B (fi) | 1978-05-31 |
FI53969C true FI53969C (fi) | 1978-09-11 |
Family
ID=27448120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI587/70A FI53969C (fi) | 1969-03-06 | 1970-03-04 | Saosom utgaongsaemne vid framstaellning av terapeutiskt vaerdefulla 2 4-diamino-5-bensylpyrimidiner anvaendbar n-substituerad beta-amino-alfa-bensylakrylnitril vilken aer vaesentligen fri fraon foeroreningar foerorsakade av beta-amino-alfa-bensylidenpropionitril-isomeren och foerfarande foer dess framstaellning |
Country Status (18)
Country | Link |
---|---|
US (1) | US3697512A (fi) |
JP (3) | JPS519747B1 (fi) |
BE (1) | BE746846A (fi) |
CH (3) | CH580082A5 (fi) |
CY (1) | CY695A (fi) |
DE (2) | DE2010166C3 (fi) |
DK (1) | DK134317B (fi) |
FI (1) | FI53969C (fi) |
FR (1) | FR2036674A5 (fi) |
GB (1) | GB1261455A (fi) |
HU (1) | HU162316B (fi) |
IE (1) | IE34044B1 (fi) |
IL (1) | IL34006A (fi) |
IT (1) | IT1008514B (fi) |
LU (1) | LU60471A1 (fi) |
NL (1) | NL171579C (fi) |
NO (1) | NO136148C (fi) |
SE (6) | SE400555B (fi) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3300939A (en) * | 1963-10-17 | 1967-01-31 | Dur O Wal National Inc | Combination adjustable tie and joint reinforcement for wall constructions |
US4052553A (en) * | 1969-03-06 | 1977-10-04 | Burroughs Wellcome Co. | 5-benzyl pyrimidines intermediates therefore, and method |
US3852276A (en) * | 1969-03-06 | 1974-12-03 | Burroughs Wellcome Co | 5-benzyl pyrimidines intermediate therefore, and method |
US3855265A (en) * | 1969-03-06 | 1974-12-17 | Burroughs Wellcome Co | 5-benzyl pyrimidines intermediates therefore, and method |
DE2051871A1 (en) * | 1969-05-16 | 1971-11-18 | The Wellcome Foundation Ltd., London | Beta-amino-alpha-aryloxymethylacrylonitrile - and 2,4-diamino-5-benzylpyrimidine derivs. useful as antibacterial agents |
BR6915082D0 (pt) | 1969-05-16 | 1973-03-08 | Wellcome Found | Processo de preparacao de benzil-pirimidinas |
GB1407971A (en) * | 1971-04-16 | 1975-10-01 | Wellcome Found | 2,4-diamino -4-3,4,5-triethoxybenzyl pyrimidine and methods of preparation therefor |
US4033962A (en) * | 1975-06-26 | 1977-07-05 | Hoffman-La Roche Inc. | 2,4-Diamino-pyrimidine derivatives and processes |
EP0001633A1 (en) * | 1977-10-18 | 1979-05-02 | The Wellcome Foundation Limited | Processes for preparing tri-heterocyclic substituted methanes and their conversion into further intermediates useful in the preparation of pharmacologically active compounds |
CH644111A5 (de) * | 1981-05-15 | 1984-07-13 | Siegfried Ag | Verfahren zur herstellung eines substituierten pyrimidins. |
FI65991C (fi) * | 1981-05-28 | 1984-08-10 | Farmos Oy | Foerfarande foer framstaellning av terapeutiskt vaerdefull 5((3,4,5-trimetoxifenyl)metyl)-2,4-pyrimidindiamin |
JPS5921346U (ja) * | 1982-08-02 | 1984-02-09 | 清水建設株式会社 | 耐火被覆吹付け装置 |
DE3603577A1 (de) * | 1986-02-06 | 1987-08-13 | Joachim K Prof Dr Seydel | Neue substituierte 2,4-diamino-5-benzylpyrimidine, deren herstellung und deren verwendung als arzneimittel mit antibakterieller wirksamkeit |
WO2005095359A1 (en) * | 2004-03-05 | 2005-10-13 | F. Hoffmann-La Roche Ag | Diaminopyrimidines as p2x3 and p2x2/3 antagonists |
FR2929239B1 (fr) † | 2008-03-31 | 2010-04-16 | Aker Yards Sa | Navire pourvu de moyens de recuperation d'energie thermique et procede correspondant |
CN101575303B (zh) * | 2008-05-05 | 2012-07-18 | 华东理工大学 | 一种3-苯胺基-2-(3,4,5-三甲氧基苄基)丙烯腈的制备方法 |
CN101328138B (zh) * | 2008-08-04 | 2013-09-18 | 寿光富康制药有限公司 | 甲氧苄啶的制备方法 |
AR090100A1 (es) * | 2012-02-21 | 2014-10-22 | Celgene Corp | Procesos para la preparacion de la (s)-1-(3-etoxi-4-metoxifenil)-2-metanosulfoniletilamina |
CN105294574B (zh) * | 2015-11-25 | 2018-06-29 | 湖南湘易康制药有限公司 | 一种甲氧苄啶的合成方法 |
CN112480012A (zh) * | 2020-12-30 | 2021-03-12 | 寿光富康制药有限公司 | 一种5-[(3,4,5-三甲氧基苯基)-甲基]-2,4-嘧啶二胺的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3049544A (en) * | 1962-08-14 | Method for the preparation of | ||
DE1303727B (de) * | 1959-09-03 | 1976-02-05 | Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London | Alpha-Arylidensubstituierte Propioni-Irile |
NL122146C (fi) * | 1960-09-02 | |||
US3485840A (en) * | 1964-11-12 | 1969-12-23 | Hoffmann La Roche | 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes |
DE1620729A1 (de) * | 1965-07-08 | 1970-08-20 | Wellcome Found | Verfahren zur Herstellung von substituierten Benzylpyrimidinen |
GB1142654A (en) * | 1965-10-28 | 1969-02-12 | Wellcome Found | Cyano-acetals and their use in benzylpyrimidine synthesis |
-
1969
- 1969-03-06 GB GB30247/69A patent/GB1261455A/en not_active Expired
-
1970
- 1970-03-04 US US16606A patent/US3697512A/en not_active Expired - Lifetime
- 1970-03-04 SE SE7002842A patent/SE400555B/xx unknown
- 1970-03-04 DE DE2010166A patent/DE2010166C3/de not_active Expired
- 1970-03-04 DE DE2066039A patent/DE2066039B2/de not_active Withdrawn
- 1970-03-04 DK DK107770AA patent/DK134317B/da not_active IP Right Cessation
- 1970-03-04 BE BE746846A patent/BE746846A/xx not_active IP Right Cessation
- 1970-03-04 FI FI587/70A patent/FI53969C/fi active
- 1970-03-04 IL IL34006A patent/IL34006A/en unknown
- 1970-03-05 IT IT49027/70A patent/IT1008514B/it active
- 1970-03-05 NO NO781/70A patent/NO136148C/no unknown
- 1970-03-05 LU LU60471D patent/LU60471A1/xx unknown
- 1970-03-05 JP JP45019010A patent/JPS519747B1/ja active Pending
- 1970-03-05 IE IE292/70A patent/IE34044B1/xx unknown
- 1970-03-06 CH CH115476A patent/CH580082A5/xx not_active IP Right Cessation
- 1970-03-06 FR FR7008182A patent/FR2036674A5/fr not_active Expired
- 1970-03-06 CH CH336770A patent/CH574399A5/xx not_active IP Right Cessation
- 1970-03-06 CH CH706281A patent/CH645884A5/de not_active IP Right Cessation
- 1970-03-06 HU HUWE438A patent/HU162316B/hu unknown
- 1970-03-06 NL NLAANVRAGE7003240,A patent/NL171579C/xx active
-
1973
- 1973-05-25 SE SE7307399A patent/SE409030B/sv unknown
- 1973-05-25 SE SE7307401A patent/SE399427B/xx unknown
- 1973-05-25 SE SE7307398A patent/SE408551B/xx unknown
- 1973-05-25 SE SE7307400A patent/SE409031B/sv unknown
- 1973-08-10 CY CY69573A patent/CY695A/xx unknown
-
1975
- 1975-03-12 JP JP50030006A patent/JPS511716B1/ja active Pending
- 1975-07-02 JP JP50081765A patent/JPS5245704B1/ja active Pending
-
1977
- 1977-09-14 SE SE7710288A patent/SE409708B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SE409708B (sv) | 1979-09-03 |
IE34044B1 (en) | 1975-01-08 |
IL34006A (en) | 1972-02-29 |
CH580082A5 (de) | 1976-09-30 |
NO136148B (no) | 1977-04-18 |
NL7003240A (fi) | 1970-09-08 |
IE34044L (en) | 1970-09-06 |
NO136148C (no) | 1977-07-27 |
CH645884A5 (de) | 1984-10-31 |
US3697512A (en) | 1972-10-10 |
DE2010166C3 (de) | 1987-01-22 |
DE2010166A1 (de) | 1970-09-17 |
SE399427B (sv) | 1978-02-13 |
CY695A (en) | 1973-08-10 |
SE408551B (sv) | 1979-06-18 |
DK134317C (fi) | 1977-03-21 |
SE409031B (sv) | 1979-07-23 |
JPS511716B1 (fi) | 1976-01-20 |
SE7710288L (sv) | 1977-09-14 |
NL171579C (nl) | 1983-04-18 |
DE2010166B2 (de) | 1978-04-27 |
BE746846A (fr) | 1970-09-04 |
GB1261455A (en) | 1972-01-26 |
HU162316B (fi) | 1973-01-29 |
JPS519747B1 (fi) | 1976-03-30 |
CH574399A5 (fi) | 1976-04-15 |
FI53969B (fi) | 1978-05-31 |
DK134317B (da) | 1976-10-18 |
SE400555B (sv) | 1978-04-03 |
LU60471A1 (fi) | 1970-09-11 |
IT1008514B (it) | 1976-11-30 |
DE2066039B2 (de) | 1979-01-11 |
JPS5245704B1 (fi) | 1977-11-17 |
FR2036674A5 (fi) | 1970-12-24 |
SE409030B (sv) | 1979-07-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI53969C (fi) | Saosom utgaongsaemne vid framstaellning av terapeutiskt vaerdefulla 2 4-diamino-5-bensylpyrimidiner anvaendbar n-substituerad beta-amino-alfa-bensylakrylnitril vilken aer vaesentligen fri fraon foeroreningar foerorsakade av beta-amino-alfa-bensylidenpropionitril-isomeren och foerfarande foer dess framstaellning | |
FI56859B (fi) | Foerfarande foer framstaellning av en elektrod foer anvaendning vid elektrolys | |
FI53923B (fi) | Isotaktisk polypropylen-monofilamentsutur och foerfarande foer framstaellning av densamma | |
FI53673C (fi) | Foerfarande foer framstaellning av kompoundstycken | |
FI53909C (fi) | Foerfarande foer behandling av mjoelk och mejeribiprodukter | |
FI53810B (fi) | Foerfarande foer avfaergning av avloppsvaetska fraon cellulosablekning | |
FI54287C (fi) | Foerfarande foer rening av raoaceton | |
FI55861C (fi) | Foerfarande foer konvertering av kolvaeten och katalytisk komposition foer utfoerande av foerfarandet | |
CH519943A (fr) | Séparateur | |
FI55915C (fi) | Anordning foer provning av relaeskydd och automatikutrustningar | |
FI53669C (fi) | Skaerhuvud foer profilspaonskaerning av rundvirke | |
FI54140B (fi) | Foerfarande foer katalytisk krackning av flera gasoljor | |
FI53941C (fi) | Anordning foer resning av kartonger | |
FI54601C (fi) | Foerfarande foer framstaellning av terapeutiskt verksamma 6-amidinopenicillansyraderivat | |
FI54038C (fi) | Anordning foer beskiktning av en fiberslang | |
FI54494C (fi) | Fraktionering av tallolja | |
FI54039C (fi) | Foerfarande och anordning foer belaeggning av fiberslang | |
FI46520B (fi) | Foerfarande foer attenuering av kalvdiarre-virus | |
FI55648B (fi) | Analogifoerfarande foer framstaellning av foerening foer behandling av bronkospastiska tillstaond | |
FI54243B (fi) | Apparat foer vaessning av slipskivor | |
FI53467C (fi) | Foerfarande foer framstaellning av bundna fiberskivor | |
FI54107B (fi) | Foerfarande foer framstaellning av butyrofenonderivat | |
FI54820C (fi) | Foerfarande foer oxidering av sulfidsvavel till polysulfidsvavel och tillvaratagande av oxidationsmedlet vid alkalisk kokning av traemassa | |
BE758266R (fr) | 2-thio-pyrimidine-nucleosides et leur | |
FI54002B (fi) | Foerfarande foer framstaellning av bestruket papper |