FI120343B - Menetelmä retrovirusproteaasi-inhibiittoreina käyttökelpoisten sulfonyylialkanoyyliaminohydroksietyyliaminojohdannaisten valmistamiseksi - Google Patents

Menetelmä retrovirusproteaasi-inhibiittoreina käyttökelpoisten sulfonyylialkanoyyliaminohydroksietyyliaminojohdannaisten valmistamiseksi Download PDF

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Publication number
FI120343B
FI120343B FI950651A FI950651A FI120343B FI 120343 B FI120343 B FI 120343B FI 950651 A FI950651 A FI 950651A FI 950651 A FI950651 A FI 950651A FI 120343 B FI120343 B FI 120343B
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FI
Finland
Prior art keywords
solution
methyl
mmol
amino
formula
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Application number
FI950651A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI950651A0 (fi
FI950651A (fi
Inventor
John J Talley
Michael L Vazquez
Gary A Decrescenzo
Richard A Mueller
Daniel Getman
John N Freskos
Original Assignee
Searle & Co
Monsanto Co
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Publication date
Application filed by Searle & Co, Monsanto Co filed Critical Searle & Co
Publication of FI950651A0 publication Critical patent/FI950651A0/fi
Publication of FI950651A publication Critical patent/FI950651A/fi
Application granted granted Critical
Publication of FI120343B publication Critical patent/FI120343B/fi

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI950651A 1992-08-25 1995-02-14 Menetelmä retrovirusproteaasi-inhibiittoreina käyttökelpoisten sulfonyylialkanoyyliaminohydroksietyyliaminojohdannaisten valmistamiseksi FI120343B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93507192A 1992-08-25 1992-08-25
US93507192 1992-08-25
PCT/US1993/007816 WO1994004493A1 (fr) 1992-08-25 1993-08-24 Sulfonylalcanoylamino hydroxyethylamino sulfamides utiles comme inhibiteurs de proteases retrovirales
US9307816 1993-08-24

Publications (3)

Publication Number Publication Date
FI950651A0 FI950651A0 (fi) 1995-02-14
FI950651A FI950651A (fi) 1995-02-14
FI120343B true FI120343B (fi) 2009-09-30

Family

ID=25466549

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950651A FI120343B (fi) 1992-08-25 1995-02-14 Menetelmä retrovirusproteaasi-inhibiittoreina käyttökelpoisten sulfonyylialkanoyyliaminohydroksietyyliaminojohdannaisten valmistamiseksi

Country Status (15)

Country Link
US (7) US5521219A (fr)
EP (1) EP0656888B1 (fr)
JP (1) JP4091654B2 (fr)
KR (1) KR100296462B1 (fr)
AT (1) ATE161828T1 (fr)
AU (1) AU669223B2 (fr)
CA (1) CA2140928C (fr)
DE (1) DE69316223T2 (fr)
DK (1) DK0656888T3 (fr)
ES (1) ES2112430T3 (fr)
FI (1) FI120343B (fr)
GR (1) GR3025958T3 (fr)
NO (1) NO303540B1 (fr)
RU (1) RU2146668C1 (fr)
WO (1) WO1994004493A1 (fr)

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US6743929B1 (en) 1992-08-25 2004-06-01 G. D. Searle & Co. Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
US7141609B2 (en) 1992-08-25 2006-11-28 G.D. Searle & Co. α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
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Also Published As

Publication number Publication date
NO303540B1 (no) 1998-07-27
WO1994004493A1 (fr) 1994-03-03
DK0656888T3 (da) 1998-02-09
AU5082093A (en) 1994-03-15
US5965588A (en) 1999-10-12
EP0656888A1 (fr) 1995-06-14
FI950651A0 (fi) 1995-02-14
US5521219A (en) 1996-05-28
ATE161828T1 (de) 1998-01-15
AU669223B2 (en) 1996-05-30
EP0656888B1 (fr) 1998-01-07
DE69316223D1 (de) 1998-02-12
KR100296462B1 (ko) 2001-10-24
CA2140928C (fr) 2008-01-29
KR950702961A (ko) 1995-08-23
CA2140928A1 (fr) 1994-02-26
US5508294A (en) 1996-04-16
US5510388A (en) 1996-04-23
US6147117A (en) 2000-11-14
GR3025958T3 (en) 1998-04-30
RU2146668C1 (ru) 2000-03-20
JP4091654B2 (ja) 2008-05-28
NO950550D0 (no) 1995-02-14
FI950651A (fi) 1995-02-14
RU95106996A (ru) 1996-11-20
ES2112430T3 (es) 1998-04-01
JPH08500825A (ja) 1996-01-30
US5760064A (en) 1998-06-02
DE69316223T2 (de) 1998-05-28
US5639769A (en) 1997-06-17
NO950550L (no) 1995-02-14

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