FI108862B - 4(p-fluorifenyyli)-3-[[3,4-(metyleenidioksi)fenoksi]metyyli]-piperidiinin N-p-halogeenibentsoyylimetyylijohdannaiset - Google Patents

4(p-fluorifenyyli)-3-[[3,4-(metyleenidioksi)fenoksi]metyyli]-piperidiinin N-p-halogeenibentsoyylimetyylijohdannaiset Download PDF

Info

Publication number
FI108862B
FI108862B FI955387A FI955387A FI108862B FI 108862 B FI108862 B FI 108862B FI 955387 A FI955387 A FI 955387A FI 955387 A FI955387 A FI 955387A FI 108862 B FI108862 B FI 108862B
Authority
FI
Finland
Prior art keywords
fluorophenyl
phenoxy
piperidines
compound
benzoylmethyl
Prior art date
Application number
FI955387A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI955387A (fi
FI955387A0 (fi
Inventor
Rafael Foguet
Santiago Gubert
Aurelio Sacristan
Jose A Ortiz
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of FI955387A publication Critical patent/FI955387A/fi
Publication of FI955387A0 publication Critical patent/FI955387A0/fi
Application granted granted Critical
Publication of FI108862B publication Critical patent/FI108862B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI955387A 1994-03-18 1995-11-08 4(p-fluorifenyyli)-3-[[3,4-(metyleenidioksi)fenoksi]metyyli]-piperidiinin N-p-halogeenibentsoyylimetyylijohdannaiset FI108862B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES9400582 1994-03-18
ES09400582A ES2102295B1 (es) 1994-03-18 1994-03-18 Nuevos compuestos derivados de la n-benzoilmetil-piperidina.
PCT/EP1995/001007 WO1995025732A1 (en) 1994-03-18 1995-03-17 N-p-HALOBENZOYLMETHYL DERIVATIVES OF 4-(p-FLUOROPHENYL)-3-((3,4-METHYLENE-DIOXY)PHENOXY)METHYL)PIPERIDINE
EP9501007 1995-03-17

Publications (3)

Publication Number Publication Date
FI955387A FI955387A (fi) 1995-11-08
FI955387A0 FI955387A0 (fi) 1995-11-08
FI108862B true FI108862B (fi) 2002-04-15

Family

ID=8285616

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955387A FI108862B (fi) 1994-03-18 1995-11-08 4(p-fluorifenyyli)-3-[[3,4-(metyleenidioksi)fenoksi]metyyli]-piperidiinin N-p-halogeenibentsoyylimetyylijohdannaiset

Country Status (19)

Country Link
US (1) US5665736A (es)
EP (1) EP0699198B1 (es)
JP (1) JP3213324B2 (es)
KR (1) KR0182093B1 (es)
AT (1) ATE181734T1 (es)
AU (1) AU678320B2 (es)
CA (1) CA2163253C (es)
DE (1) DE69510510T2 (es)
DK (1) DK0699198T3 (es)
ES (1) ES2102295B1 (es)
FI (1) FI108862B (es)
GR (1) GR3031282T3 (es)
IL (1) IL112763A (es)
NO (1) NO308002B1 (es)
NZ (1) NZ283130A (es)
PH (1) PH31388A (es)
TW (1) TW416956B (es)
WO (1) WO1995025732A1 (es)
ZA (1) ZA951963B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2117557B1 (es) * 1996-02-29 1999-07-01 Ferrer Int Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina.
EP1384720A1 (en) 1996-06-13 2004-01-28 SUMIKA FINE CHEMICALS Co., Ltd. Process for drying paroxetine hydrochloride
GB9623359D0 (en) * 1996-11-09 1997-01-08 Smithkline Beecham Plc Novel process
GB9700690D0 (en) 1997-01-15 1997-03-05 Smithkline Beecham Plc Novel process
HUP0003958A3 (en) 1997-05-29 2001-06-28 Smithkline Beecham Plc Process for preparation of 4-aryl-piperidines and intermediates
GB9826175D0 (en) * 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
US7294637B2 (en) 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
JP2004509103A (ja) 2000-09-11 2004-03-25 セプレイコー　インコーポレイテッド モノアミン受容体及び輸送体のリガンドならびにその使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
EP0190496A3 (en) * 1984-12-13 1987-05-27 Beecham Group Plc Piperidine derivatives having a gastro-intestinal activity
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
DK231088D0 (da) * 1988-04-28 1988-04-28 Ferrosan As Piperidinforbindelser, deres fremstilling og anvendelse
IE66332B1 (en) * 1986-11-03 1995-12-27 Novo Nordisk As Piperidine compounds and their preparation and use
US5017585A (en) * 1986-11-03 1991-05-21 Novo Nordisk A/S Method of treating calcium overload

Also Published As

Publication number Publication date
GR3031282T3 (en) 1999-12-31
CA2163253A1 (en) 1995-09-28
JP3213324B2 (ja) 2001-10-02
WO1995025732A1 (en) 1995-09-28
AU2109495A (en) 1995-10-09
US5665736A (en) 1997-09-09
DE69510510T2 (de) 1999-11-18
FI955387A (fi) 1995-11-08
TW416956B (en) 2001-01-01
KR960702456A (ko) 1996-04-27
AU678320B2 (en) 1997-05-22
PH31388A (en) 1998-10-29
ZA951963B (en) 1996-03-11
EP0699198A1 (en) 1996-03-06
FI955387A0 (fi) 1995-11-08
DK0699198T3 (da) 1999-11-22
KR0182093B1 (ko) 1999-05-01
IL112763A0 (en) 1995-05-26
JPH08510477A (ja) 1996-11-05
ATE181734T1 (de) 1999-07-15
NZ283130A (en) 1996-11-26
ES2102295B1 (es) 1998-04-01
DE69510510D1 (de) 1999-08-05
NO308002B1 (no) 2000-07-03
CA2163253C (en) 2004-08-10
ES2102295A1 (es) 1997-07-16
IL112763A (en) 1998-03-10
EP0699198B1 (en) 1999-06-30
NO954538D0 (no) 1995-11-10
NO954538L (no) 1995-11-10

Similar Documents

Publication Publication Date Title
US6498168B2 (en) Muscarinic antagonists
KR100322415B1 (ko) 1-[(4-클로로페닐)페닐메틸]-4-[(4-메틸페닐)술포닐]피페라진의거울상이성체
KR920005113B1 (ko) 정신병치료제 1-플루오로페닐부틸-4-(2-피리미디닐)피페라진 유도체의 제조방법.
HU230189B1 (hu) Szerotonin újrafelvételt gátló fenilpiperazin-származékok
KR20010043032A (ko) 1-[(1-치환-4-피페리디닐)메틸]-4-피페리딘 유도체, 그의제조방법, 그것을 함유하는의약조성물 및 이 화합물의중간체
SK50192004A3 (sk) Spôsob prípravy (S)-4-amino-5-chlór-2-metoxy-N-[1-[1-(2- tetrahydrofurylkarbonyl)-4-piperidinylmethyl]-4- piperidinyl]benzamidu, farmaceutický prostriedok obsahujúci tento derivát a opis medziproduktu tohto derivátu
FI108862B (fi) 4(p-fluorifenyyli)-3-[[3,4-(metyleenidioksi)fenoksi]metyyli]-piperidiinin N-p-halogeenibentsoyylimetyylijohdannaiset
US6355642B1 (en) Tetrahydrobenzindole compounds
JPH0710853B2 (ja) チアジン（又はオキサジン）誘導体、その製法及びその合成中間体
HU176533B (en) Process for preparing o-alkylated hydroxylamines
EP2417124B1 (en) Serotonin and norepinephrine reuptake inhibitor
JPH05509311A (ja) １，４―二置換ピペラジン
KR100924405B1 (ko) 뉴로키닌 수용체 길항제로서의 신규한ｎ-트리아졸일메틸-피페라진 유도체
WO1998031669A1 (fr) Nouvelles arylpiperazines derivees de piperidine comme medicaments antidepresseurs
WO2005094896A2 (en) Targeted serotonin reuptake inhibitors
Biasotti et al. Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase
FR2862967A1 (fr) Derives de (4-phenylpiperazin-1-yl)acylpiperidine, leur preparation et leur application en therapeutique
KR20010006587A (ko) 시아노-인돌 세로토닌 재흡수 억제 화합물, 이의 제조방법 및 이를 함유하는 약제학적 조성물
RU2123001C1 (ru) N - оксиды 4-фенилпиперазинов и 4-фенилпиперидинов, композиция на их основе и способ ингибирования допамин-2 рецепторов
TW444012B (en) Chromene derivatives and salts thereof, and pharmaceuticals containing the same
KR101651994B1 (ko) 아릴옥시 아제티딘 화합물, 및 이를 포함하는 약학 조성물
MX2011001846A (es) Nuevos derivados de piperidina-4-acetamida y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina.
KR101561992B1 (ko) 3-아미노메틸 아제티딘 화합물, 이를 포함하는 우울증, 정신 질환, 조루증, 또는 신경병증성 통증의 예방 또는 치료용 약학 조성물, 및 상기 약학 조성물을 포함하는 제제
MX2011001847A (es) Nuevos derivados de piperidina-propionamida y su uso como inhibidores de la reabsorcion del neurotransmisor de monoamina.
KR101426408B1 (ko) 4각 고리 질소 화합물, 이를 포함하는 우울증, 정신 질환, 조루증, 또는 신경병증성 통증의 예방 또는 치료용 약학 조성물, 및 상기 약학 조성물을 포함하는 제제

Legal Events

Date Code Title Description
MA Patent expired