FI108539B - Parannettu menetelmä (4R-cis)-1,1-dimetyylietyyli-6-syanometyyli-2,2-dimetyyli-1,3-dioksaani-4-asetaatin syntetisoimiseksi - Google Patents

Parannettu menetelmä (4R-cis)-1,1-dimetyylietyyli-6-syanometyyli-2,2-dimetyyli-1,3-dioksaani-4-asetaatin syntetisoimiseksi Download PDF

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Publication number
FI108539B
FI108539B FI931680A FI931680A FI108539B FI 108539 B FI108539 B FI 108539B FI 931680 A FI931680 A FI 931680A FI 931680 A FI931680 A FI 931680A FI 108539 B FI108539 B FI 108539B
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Finland
Prior art keywords
formula
dimethyl
acetate
cis
compound
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FI931680A
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English (en)
Finnish (fi)
Swedish (sv)
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FI931680A0 (fi
FI931680A (fi
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Donald Eugene Butler
Alan Millar
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Warner Lambert Co
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Publication of FI931680A publication Critical patent/FI931680A/fi
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Publication of FI108539B publication Critical patent/FI108539B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FI931680A 1990-10-17 1993-04-14 Parannettu menetelmä (4R-cis)-1,1-dimetyylietyyli-6-syanometyyli-2,2-dimetyyli-1,3-dioksaani-4-asetaatin syntetisoimiseksi FI108539B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US59952190 1990-10-17
US07/599,521 US5103024A (en) 1990-10-17 1990-10-17 Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
US9106697 1991-09-11
PCT/US1991/006697 WO1992006968A1 (en) 1990-10-17 1991-09-11 Process for the synthesis of (4r-cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate

Publications (3)

Publication Number Publication Date
FI931680A0 FI931680A0 (fi) 1993-04-14
FI931680A FI931680A (fi) 1993-04-14
FI108539B true FI108539B (fi) 2002-02-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
FI931680A FI108539B (fi) 1990-10-17 1993-04-14 Parannettu menetelmä (4R-cis)-1,1-dimetyylietyyli-6-syanometyyli-2,2-dimetyyli-1,3-dioksaani-4-asetaatin syntetisoimiseksi

Country Status (20)

Country Link
US (1) US5103024A (cs)
EP (1) EP0553213B1 (cs)
JP (1) JP3105923B2 (cs)
KR (1) KR0166385B1 (cs)
AT (1) ATE118772T1 (cs)
AU (1) AU646311B2 (cs)
CA (1) CA2092997C (cs)
CZ (5) CZ282992B6 (cs)
DE (1) DE69107622T2 (cs)
DK (1) DK0553213T3 (cs)
ES (1) ES2070519T3 (cs)
FI (1) FI108539B (cs)
HK (1) HK1005026A1 (cs)
HU (2) HU213731B (cs)
IE (1) IE62940B1 (cs)
NO (1) NO301588B1 (cs)
PT (1) PT99244B (cs)
RU (1) RU2067580C1 (cs)
SK (5) SK280942B6 (cs)
WO (1) WO1992006968A1 (cs)

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HU227124B1 (en) * 2001-09-14 2010-07-28 Egis Gyogyszergyar Nyilvanosan Polymorphs of 1-pyrrole derivative, intermediate for the preparation of atorvastatin
UA77990C2 (en) * 2001-12-12 2007-02-15 Crystalline calcium salt of (2:1) [r-(r*,r*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrroleheptanic acid
CZ296967B6 (cs) * 2002-02-01 2006-08-16 Zentiva, A.S. Zpusob výroby amorfní formy hemivápenaté soli (3R,5R) 7-[3-fenyl-4-fenylkarbamoyl-2-(4-fluorfenyl)-5-isopropylpyrrol-1-yl]-3,5-dihydroxyheptanové kyseliny (atorvastatinu)
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KR100529703B1 (ko) * 2002-09-23 2005-11-17 임광민 키랄 중간체의 제조방법 및 그를 이용한 아토바스타틴의제조방법
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CN1774421A (zh) * 2003-04-14 2006-05-17 沃尼尔·朗伯有限责任公司 制备5－(4－氟苯基)－1－[2－((2r,4r)－4－羟基－6－氧代－四氢－吡喃－2－基)乙基]－2－异丙基－4－苯基－1h－吡咯－3－羧酸苯基酰胺的方法
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Also Published As

Publication number Publication date
PT99244A (pt) 1992-09-30
US5103024A (en) 1992-04-07
CZ124797A3 (en) 1997-12-17
HUT64049A (en) 1993-11-29
NO931421D0 (no) 1993-04-16
PT99244B (pt) 1999-04-30
SK280942B6 (sk) 2000-09-12
CZ61493A3 (en) 1994-02-16
JP3105923B2 (ja) 2000-11-06
WO1992006968A1 (en) 1992-04-30
EP0553213A1 (en) 1993-08-04
CZ282993B6 (cs) 1997-12-17
FI931680A0 (fi) 1993-04-14
CZ124597A3 (en) 1997-12-17
HU219237B (en) 2001-03-28
IE913629A1 (en) 1992-04-22
SK280939B6 (sk) 2000-09-12
HU9701183D0 (en) 1997-09-29
CZ124697A3 (en) 1997-12-17
AU8848091A (en) 1992-05-20
CZ282994B6 (cs) 1997-12-17
SK280940B6 (sk) 2000-09-12
CA2092997A1 (en) 1992-04-18
FI931680A (fi) 1993-04-14
KR0166385B1 (en) 1999-01-15
SK280938B6 (sk) 2000-09-12
DK0553213T3 (da) 1995-07-17
KR930702328A (ko) 1993-09-08
RU2067580C1 (ru) 1996-10-10
DE69107622T2 (de) 1995-07-06
IE62940B1 (en) 1995-03-08
ATE118772T1 (de) 1995-03-15
SK280941B6 (sk) 2000-09-12
AU646311B2 (en) 1994-02-17
HK1005026A1 (en) 1998-12-18
CZ282922B6 (cs) 1997-11-12
DE69107622D1 (de) 1995-03-30
ES2070519T3 (es) 1995-06-01
HU213731B (en) 1997-09-29
JPH06502162A (ja) 1994-03-10
CZ282992B6 (cs) 1997-12-17
SK33993A3 (en) 1993-10-06
EP0553213B1 (en) 1995-02-22
NO301588B1 (no) 1997-11-17
CZ283003B6 (cs) 1997-12-17
NO931421L (no) 1993-06-16
CZ209495A3 (en) 1997-12-17
HU9301122D0 (en) 1993-08-30
CA2092997C (en) 2002-05-14

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