AU2003251523A1 - Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid - Google Patents
Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acidInfo
- Publication number
- AU2003251523A1 AU2003251523A1 AU2003251523A AU2003251523A AU2003251523A1 AU 2003251523 A1 AU2003251523 A1 AU 2003251523A1 AU 2003251523 A AU2003251523 A AU 2003251523A AU 2003251523 A AU2003251523 A AU 2003251523A AU 2003251523 A1 AU2003251523 A1 AU 2003251523A1
- Authority
- AU
- Australia
- Prior art keywords
- cyano
- ethyl
- processes
- making
- hydroxybutyric acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
- C12P13/004—Cyanohydrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38931702P | 2002-06-13 | 2002-06-13 | |
US60/389,317 | 2002-06-13 | ||
US39294402P | 2002-06-28 | 2002-06-28 | |
US60/392,944 | 2002-06-28 | ||
PCT/US2003/018840 WO2003106415A2 (en) | 2002-06-13 | 2003-06-13 | Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2003251523A1 true AU2003251523A1 (en) | 2003-12-31 |
AU2003251523A8 AU2003251523A8 (en) | 2003-12-31 |
Family
ID=29740129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2003251523A Abandoned AU2003251523A1 (en) | 2002-06-13 | 2003-06-13 | Processes for making (r)-ethyl 4-cyano-3-hydroxybutyric acid |
Country Status (3)
Country | Link |
---|---|
US (3) | US7932064B2 (en) |
AU (1) | AU2003251523A1 (en) |
WO (1) | WO2003106415A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602004021778D1 (en) | 2003-02-27 | 2009-08-13 | Basf Se | MODIFIED NITRILASES AND THEIR USE IN PROCEDURES FOR THE PREPARATION OF CARBOXYLIC ACIDS |
US20100267100A1 (en) * | 2007-03-21 | 2010-10-21 | Ling Hua | Enzymatic synthesis of optically pure beta-hydroxy carboxylic acids and their derivatives |
US20090004720A1 (en) * | 2007-06-26 | 2009-01-01 | Ling Hua | Smart Biocatalysts For Organic Synthesis |
CN101875907B (en) * | 2009-04-28 | 2013-07-10 | 上海市农药研究所 | Microbial strain capable of hydrolyzing 3-hydroxybutyronitrile |
CN113195727A (en) * | 2018-10-18 | 2021-07-30 | 巴斯夫欧洲公司 | Process for producing acrylic acid or a salt thereof |
CN115093497A (en) * | 2019-09-05 | 2022-09-23 | 大连合元医疗器械有限公司 | Poly (2-cyanoacrylate) and application thereof in embolization microspheres |
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US4611067A (en) | 1985-01-31 | 1986-09-09 | Merck & Co., Inc. | Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein |
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US5206158A (en) | 1986-07-02 | 1993-04-27 | Gist-Brocades N.V. | Process for the preparation of difluorobenzamide |
US5124482A (en) | 1988-02-22 | 1992-06-23 | Warner-Lambert Company | Process for trans-6-(2-substituted-pyrrol-1-yl)alkyl)pyran-2-one inhibitors of cholesterol synthesis |
US5003080A (en) | 1988-02-22 | 1991-03-26 | Warner-Lambert Company | Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis |
US5216174A (en) | 1988-02-22 | 1993-06-01 | Warner-Lambert Co. | Process for trans-6-[12-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
US5245047A (en) | 1988-02-22 | 1993-09-14 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
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US5149837A (en) | 1988-02-22 | 1992-09-22 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
JP2670838B2 (en) | 1988-03-08 | 1997-10-29 | 株式会社ジャパンエナジー | Method for producing L-α-amino acids |
JPH0479894A (en) | 1990-07-19 | 1992-03-13 | Nikko Kyodo Co Ltd | Production of d-alanine |
DE68926922T2 (en) | 1988-03-08 | 1996-12-19 | Japan Energy Corp | Process for the production of L-alpha amino acids |
US5587303A (en) | 1988-03-08 | 1996-12-24 | Nippon Mining Company, Ltd. | Production process of L-amino acids with bacteria |
DE69031711T2 (en) | 1989-08-09 | 1998-04-09 | Dekalb Genetics Corp | METHODS AND COMPOSITIONS FOR THE PRODUCTION OF STABLY TRANSFORMED, FERTILIZABLE CORN PLANTS AND CELLS THEREFOR |
DK589389D0 (en) | 1989-11-23 | 1989-11-23 | Novo Nordisk As | IMMOBILIZED ENZYME PREPARATION |
BR9007089A (en) | 1989-11-27 | 1991-11-26 | Geobiotics Inc | PROCESSES TO RECOVER AND RECONCENTRATE GOLD FROM ITS ORES |
EP0449648B1 (en) | 1990-03-30 | 1999-05-12 | Nitto Chemical Industry Co., Ltd. | Process for producing R(-)-mandelic acid and derivatives thereof |
JP2696424B2 (en) | 1990-08-16 | 1998-01-14 | 日東化学工業株式会社 | Method for producing R (-)-mandelic acid |
US5103024A (en) | 1990-10-17 | 1992-04-07 | Warner-Lambert Company | Process for the synthesis of (4r-cis)-1,1-dimethylethyl 6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate |
US5248793A (en) | 1990-10-17 | 1993-09-28 | Warner-Lambert Company | Process for the synthesis of (4R-cis)-1,1-dimethylethyl 6-iodomethyl or 6-(phenyl-substituted)sulfonyloxymethyl-2,2-dimethyl-1,3-dioxane-4-acetate |
EP0502476B1 (en) | 1991-03-04 | 2001-07-18 | Mitsubishi Rayon Co., Ltd. | Hybrid plasmid vectors containing genes encoding nitrile degrading enzymes and methods of producing amides and acids |
JP3171931B2 (en) * | 1992-06-02 | 2001-06-04 | 高砂香料工業株式会社 | (R)-(-)-4-cyano-3-hydroxybutyric acid t-butyl ester and method for producing the same |
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JP3218133B2 (en) | 1993-02-03 | 2001-10-15 | 三菱レイヨン株式会社 | Method for producing optically active α-hydroxycarboxylic acid having phenyl group |
JP2720140B2 (en) | 1993-02-03 | 1998-02-25 | 日東化学工業株式会社 | Method for producing optically active α-hydroxycarboxylic acid having phenyl group |
US5298627A (en) | 1993-03-03 | 1994-03-29 | Warner-Lambert Company | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis |
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JP3119468B2 (en) | 1994-11-09 | 2000-12-18 | 三菱レイヨン株式会社 | Method for producing optically active α-hydroxy acid or α-hydroxyamide |
NL1000360C2 (en) * | 1995-05-15 | 1996-11-18 | Akzo Nobel Nv | Process for the preparation of pyridine-2,6-diamines |
US5811515A (en) | 1995-06-12 | 1998-09-22 | California Institute Of Technology | Synthesis of conformationally restricted amino acids, peptides, and peptidomimetics by catalytic ring closing metathesis |
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US5756306A (en) | 1995-11-10 | 1998-05-26 | Nitto Chemical Industry Co., Ltd. | Process for producing a-hydroxy acid or a-hydroxyamide by microorganism |
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US5932212A (en) | 1996-05-24 | 1999-08-03 | Altus Biologics, Inc. | Crosslinked protein crystal formulations and their use as catalysts in organic solvents |
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US6492578B1 (en) | 1998-07-10 | 2002-12-10 | Calgene Llc | Expression of herbicide tolerance genes in plant plastids |
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US20040014195A1 (en) * | 1999-12-29 | 2004-01-22 | Diversa Corporation | Nitrilases, nucleic acids encoding them and methods for making and using them |
US7300775B2 (en) * | 1999-12-29 | 2007-11-27 | Verenium Corporation | Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents |
US20040002147A1 (en) | 1999-12-29 | 2004-01-01 | Desantis Grace | Nitrilases |
EP1320749A2 (en) | 2000-09-05 | 2003-06-25 | The Althexis Company | Drug discover employing calorimetric target triage |
AU2001296653A1 (en) | 2000-10-04 | 2002-04-15 | Maxygen, Inc. | Enantioselective production of amino carboxylic acids |
US20020127609A1 (en) | 2001-02-23 | 2002-09-12 | Maxygen, Inc. | Screening for enzyme stereoselectivity utilizing mass spectrometry |
EP1578910A4 (en) | 2001-06-21 | 2008-06-04 | Verenium Corp | Nitrilases |
WO2003004456A1 (en) | 2001-07-06 | 2003-01-16 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of 7-amino syn 3,5-dihydroxy heptanoic acid derivatives via 6-cyano syn 3,5-dihydroxy hexanoic acid derivatives |
WO2004096988A2 (en) | 2003-04-25 | 2004-11-11 | Dow Global Technologies Inc | Discovery of biocatalysts and biocatalytic activities using nuclear magnetic resonance |
-
2003
- 2003-06-13 AU AU2003251523A patent/AU2003251523A1/en not_active Abandoned
- 2003-06-13 US US10/461,925 patent/US7932064B2/en not_active Expired - Fee Related
- 2003-06-13 WO PCT/US2003/018840 patent/WO2003106415A2/en not_active Application Discontinuation
-
2011
- 2011-03-22 US US13/053,404 patent/US8372608B2/en not_active Expired - Fee Related
-
2013
- 2013-01-25 US US13/750,122 patent/US20130130333A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7932064B2 (en) | 2011-04-26 |
WO2003106415A3 (en) | 2004-07-01 |
WO2003106415A2 (en) | 2003-12-24 |
AU2003251523A8 (en) | 2003-12-31 |
US20110250657A1 (en) | 2011-10-13 |
US20040053378A1 (en) | 2004-03-18 |
US8372608B2 (en) | 2013-02-12 |
US20130130333A1 (en) | 2013-05-23 |
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