ES8704486A1 - Procedimiento de preparar derivados rodaninicos. - Google Patents
Procedimiento de preparar derivados rodaninicos.Info
- Publication number
- ES8704486A1 ES8704486A1 ES551410A ES551410A ES8704486A1 ES 8704486 A1 ES8704486 A1 ES 8704486A1 ES 551410 A ES551410 A ES 551410A ES 551410 A ES551410 A ES 551410A ES 8704486 A1 ES8704486 A1 ES 8704486A1
- Authority
- ES
- Spain
- Prior art keywords
- preparing same
- formula
- rhodanine derivatives
- chem
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS RODANINICOS, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I), EN LA QUE R1 ES ALQUILO INFERIOR; Y B ES UN RADICAL, CON UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R2 ES HIDROGENO. EL PRODUCTO OBTENIDO SE SOMETE A UNA REACCION DE REDUCCION Y, SI SE DESEA, EL PRODUCTO OBTENIDO SE HACE REACCIONAR CON UNA BASE. DE APLICACION EN EL TRATAMIENTO DE LAS COMPLICACIONES DEBIDAS A LA REDUCTASA ALDOSA, PRODUCIDAS EN EL TRATAMIENTO DE LA DIABETES.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60152632A JPS6212776A (ja) | 1985-07-10 | 1985-07-10 | ロ−ダニン誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES551410A0 ES551410A0 (es) | 1987-04-16 |
ES8704486A1 true ES8704486A1 (es) | 1987-04-16 |
Family
ID=15544630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES551410A Expired ES8704486A1 (es) | 1985-07-10 | 1986-01-15 | Procedimiento de preparar derivados rodaninicos. |
Country Status (8)
Country | Link |
---|---|
US (2) | US4714765A (es) |
EP (2) | EP0208040B1 (es) |
JP (1) | JPS6212776A (es) |
KR (1) | KR910006638B1 (es) |
AU (1) | AU556518B1 (es) |
CA (1) | CA1264758A1 (es) |
DE (1) | DE3583803D1 (es) |
ES (1) | ES8704486A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI91869C (fi) * | 1987-03-18 | 1994-08-25 | Tanabe Seiyaku Co | Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi |
US4897406A (en) * | 1987-11-13 | 1990-01-30 | Nisshin Flour Milling Co., Ltd. | Rhodanine derivatives and pharmaceutical compositions |
JP2835545B2 (ja) * | 1990-11-27 | 1998-12-14 | 株式会社大塚製薬工場 | 白内障予防及び治療剤 |
JP2835547B2 (ja) * | 1991-12-25 | 1998-12-14 | 株式会社大塚製薬工場 | 糖尿病治療剤 |
EP0587377A3 (en) * | 1992-09-10 | 1994-09-21 | Lilly Co Eli | Thiazolidinone derivatives as hypoglycemic agents and for treating alzheimer's disease |
US6251928B1 (en) | 1994-03-16 | 2001-06-26 | Eli Lilly And Company | Treatment of alzheimer's disease employing inhibitors of cathepsin D |
BR9609744A (pt) * | 1995-07-31 | 1999-03-02 | Shionogi & Co | Derivados de pirrolidina tendo atividade inibitória de fosfolipase a2 |
WO2000018747A1 (en) * | 1998-09-30 | 2000-04-06 | Roche Diagnostics Gmbh | Rhodanine carboxylic acid derivatives for the treatment and prevention of metabolic bone disorders |
AU2002215218A1 (en) | 2000-11-17 | 2002-05-27 | Takeda Chemical Industries Ltd. | Isoxazole derivatives |
KR101095734B1 (ko) | 2009-01-23 | 2011-12-21 | 숙명여자대학교산학협력단 | 신규한 로다닌 유도체와 이의 의약적 용도 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB489335A (en) * | 1937-01-22 | 1938-07-22 | Douglas James Fry | Improvements in or relating to the manufacture and use of dyestuffs suitable for sensitising photographic emulsions |
SU467058A1 (ru) * | 1973-09-20 | 1975-04-15 | Московский Ордена Трудового Красного Знамени Институт Нефтехимической И Газовой Промышленности Им.И.М.Губкина | Способ получени смеси бисфенолов |
JPS5430171A (en) * | 1977-08-10 | 1979-03-06 | Taiho Pharmaceutical Co Ltd | Isooxazole derivative and production |
JPS5728074A (en) | 1980-07-28 | 1982-02-15 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation, and inhibitor for aldose reducing enzyme consisting essentially of it |
JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
JPS6127984A (ja) * | 1984-07-16 | 1986-02-07 | Taiho Yakuhin Kogyo Kk | ロ−ダニン酢酸誘導体 |
JPH0638665B2 (ja) * | 1985-07-08 | 1994-05-18 | 松下電器産業株式会社 | リニア信号処理回路 |
-
1985
- 1985-07-10 JP JP60152632A patent/JPS6212776A/ja active Granted
- 1985-12-19 US US06/810,594 patent/US4714765A/en not_active Expired - Fee Related
- 1985-12-23 AU AU51598/85A patent/AU556518B1/en not_active Ceased
- 1985-12-23 EP EP85309401A patent/EP0208040B1/en not_active Expired - Lifetime
- 1985-12-23 EP EP87201399A patent/EP0258914A3/en not_active Withdrawn
- 1985-12-23 DE DE8585309401T patent/DE3583803D1/de not_active Expired - Fee Related
- 1985-12-31 KR KR1019850010103A patent/KR910006638B1/ko not_active IP Right Cessation
-
1986
- 1986-01-06 CA CA000499002A patent/CA1264758A1/en active Granted
- 1986-01-15 ES ES551410A patent/ES8704486A1/es not_active Expired
-
1987
- 1987-04-27 US US07/043,217 patent/US4777259A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES551410A0 (es) | 1987-04-16 |
EP0258914A2 (en) | 1988-03-09 |
CA1266273C (es) | 1990-02-27 |
JPH0574591B2 (es) | 1993-10-18 |
EP0208040B1 (en) | 1991-08-14 |
US4714765A (en) | 1987-12-22 |
AU556518B1 (en) | 1986-11-06 |
CA1264758A1 (en) | 1990-01-23 |
US4777259A (en) | 1988-10-11 |
EP0208040A2 (en) | 1987-01-14 |
KR910006638B1 (ko) | 1991-08-29 |
JPS6212776A (ja) | 1987-01-21 |
EP0258914A3 (en) | 1988-11-17 |
DE3583803D1 (de) | 1991-09-19 |
KR870001204A (ko) | 1987-03-12 |
EP0208040A3 (en) | 1988-03-16 |
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