ES8701143A1 - Un procedimiento para la preparacion de nuevos aminas terciarias. - Google Patents
Un procedimiento para la preparacion de nuevos aminas terciarias.Info
- Publication number
- ES8701143A1 ES8701143A1 ES545365A ES545365A ES8701143A1 ES 8701143 A1 ES8701143 A1 ES 8701143A1 ES 545365 A ES545365 A ES 545365A ES 545365 A ES545365 A ES 545365A ES 8701143 A1 ES8701143 A1 ES 8701143A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy
- aryloxypropyl
- substituted
- hyperglycaemic
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Detergent Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS AMINAS TERCIARIAS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III) PARA OBTENER AMINAS TERCIARIAS DE FORMULA (I) O UNA DE SUS SALES FARMACEUTICAMENTE ACEPTABLES; DONDE R1 ES UN GRUPO 2-HIDROXI-2-(BENZOFURAN-2-IL)ETILO Y OTROS; R2 ES UN GRUPO DE HIDROGENO O UN GRUPO METILO; D ES UN RADICAL BENZOFURAN-2-ILO Y OTROS; R4 ES UN RADICAL -(CH2)ACOOH, -O(CH2)BCOOH Y OTROS; R4K ES UN ATOMO DE HIDROGENO O DE HALOGENO O UN RADICAL ALQUILO INFERIOR O ALCOXI INFERIOR Y OTROS; N ES 1 O 2; M ES 0 O 1, CON LA CONDICION DE QUE NBM ES 1 O 2; Q1 ES UN ATOMO DE HIDROGENO; Y Q2 ES UN GRUPO HIDROXI O UN ESTER HIDROLIZABLE IN-VIVO. TIENEN APLICACION EN MEDICINA Y AGRICULTURA POR SU ACTIVIDAD ANTI-HIPERGLICEMICA Y/O ANTI-OBESIDAD.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848418472A GB8418472D0 (en) | 1984-07-19 | 1984-07-19 | Compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8701143A1 true ES8701143A1 (es) | 1986-11-16 |
ES545365A0 ES545365A0 (es) | 1986-11-16 |
Family
ID=10564149
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES545365A Expired ES8701143A1 (es) | 1984-07-19 | 1985-07-18 | Un procedimiento para la preparacion de nuevos aminas terciarias. |
ES552860A Expired ES8705362A1 (es) | 1984-07-19 | 1986-03-10 | Un procedimiento para la preparacion de nuevas aminas terciarias |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552860A Expired ES8705362A1 (es) | 1984-07-19 | 1986-03-10 | Un procedimiento para la preparacion de nuevas aminas terciarias |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0170121B1 (es) |
JP (1) | JPS6176446A (es) |
AT (1) | ATE64590T1 (es) |
AU (1) | AU4517385A (es) |
DE (1) | DE3583261D1 (es) |
DK (1) | DK325385A (es) |
ES (2) | ES8701143A1 (es) |
GB (1) | GB8418472D0 (es) |
GR (1) | GR851779B (es) |
PT (1) | PT80835B (es) |
ZA (1) | ZA855400B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5166218A (en) * | 1983-10-19 | 1992-11-24 | Hoffmann-La Roche Inc. | Phenoxypropanolamines and pharmaceutical compositions thereof |
CA1262729A (en) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
CA1337429C (en) * | 1983-12-05 | 1995-10-24 | Guy Rosalia Eugene Van Lommen | Derivatives of 2,2'-iminobisethanol |
GB8620951D0 (en) * | 1986-08-29 | 1986-10-08 | Beecham Group Plc | Compounds |
DE3866984D1 (en) * | 1987-07-21 | 1992-01-30 | Hoffmann La Roche | Phenoxypropanolamine. |
US5321036A (en) * | 1993-02-10 | 1994-06-14 | Bristol-Myers Squibb Company | Thiazole and oxazole-based β3 adrenergic receptor agonists |
US5578638A (en) * | 1993-11-05 | 1996-11-26 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists |
US5563171A (en) * | 1993-11-05 | 1996-10-08 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists |
AU4320297A (en) * | 1996-09-26 | 1998-04-17 | Kissei Pharmaceutical Co. Ltd. | 2-amino-1-(4-hydroxy-2-methylphenyl)propanol derivatives |
MY126489A (en) * | 1998-07-08 | 2006-10-31 | Kissei Pharmaceutical | Phenoxyacetic acid derivatives and medicinal compositions containing the same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
DE3368258D1 (en) * | 1982-07-16 | 1987-01-22 | Beecham Group Plc | 2-aminoethyl ether derivatives, processes for their preparation and pharmaceutical compositions containing them |
CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
CA1262729A (en) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
-
1984
- 1984-07-19 GB GB848418472A patent/GB8418472D0/en active Pending
-
1985
- 1985-07-10 DE DE8585108609T patent/DE3583261D1/de not_active Expired - Fee Related
- 1985-07-10 EP EP85108609A patent/EP0170121B1/en not_active Expired - Lifetime
- 1985-07-10 AT AT85108609T patent/ATE64590T1/de active
- 1985-07-17 DK DK325385A patent/DK325385A/da not_active Application Discontinuation
- 1985-07-17 GR GR851779A patent/GR851779B/el unknown
- 1985-07-17 ZA ZA855400A patent/ZA855400B/xx unknown
- 1985-07-18 PT PT80835A patent/PT80835B/pt unknown
- 1985-07-18 JP JP60157137A patent/JPS6176446A/ja active Pending
- 1985-07-18 ES ES545365A patent/ES8701143A1/es not_active Expired
- 1985-07-19 AU AU45173/85A patent/AU4517385A/en not_active Abandoned
-
1986
- 1986-03-10 ES ES552860A patent/ES8705362A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0170121B1 (en) | 1991-06-19 |
PT80835A (en) | 1985-08-01 |
DK325385A (da) | 1986-01-20 |
PT80835B (en) | 1987-03-23 |
JPS6176446A (ja) | 1986-04-18 |
GR851779B (es) | 1985-11-26 |
ES8705362A1 (es) | 1987-05-01 |
DK325385D0 (da) | 1985-07-17 |
EP0170121A1 (en) | 1986-02-05 |
ES545365A0 (es) | 1986-11-16 |
ZA855400B (en) | 1986-05-28 |
AU4517385A (en) | 1986-01-23 |
ES552860A0 (es) | 1987-05-01 |
GB8418472D0 (en) | 1984-08-22 |
ATE64590T1 (de) | 1991-07-15 |
DE3583261D1 (de) | 1991-07-25 |
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