ES8605286A1 - Procedimiento para la fabricacion de nuevos sulfatos de xi- lanos de bajo peso molecular - Google Patents

Procedimiento para la fabricacion de nuevos sulfatos de xi- lanos de bajo peso molecular

Info

Publication number
ES8605286A1
ES8605286A1 ES548577A ES548577A ES8605286A1 ES 8605286 A1 ES8605286 A1 ES 8605286A1 ES 548577 A ES548577 A ES 548577A ES 548577 A ES548577 A ES 548577A ES 8605286 A1 ES8605286 A1 ES 8605286A1
Authority
ES
Spain
Prior art keywords
molecular weight
xylanes
sulphated
preparation
low molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548577A
Other languages
English (en)
Other versions
ES548577A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Sclavo SpA
Original Assignee
Sanofi SA
Sclavo SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA, Sclavo SpA filed Critical Sanofi SA
Publication of ES548577A0 publication Critical patent/ES548577A0/es
Publication of ES8605286A1 publication Critical patent/ES8605286A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

METODO DE PRODUCCION DE SULFATOS DE XILANOS DE BAJO PESO MOLECULAR CON UN GRADO DE SULFATACION MEDIO COMPRENDIDO ENTRE 1,5 Y 2, UN PORCENTAJE DE ACIDOS URONICOS COMPRENDIDO ENTRE 0 Y 10 Y UN PORCENTAJE DE PENTOSAS COMPRENDIDO ENTRE 30 Y 40. CONSISTE EN SOMETER EL POLISULFATO DE XILANO SP54 DIRECTAMENTE A UN FRACCIONAMIENTO POR ULTRAFILTRACION SOBRE MEMBRANAS O FIBRAS HUECAS DE DIFERENTES PEROSIDADES, A UNA PRESION MEDIA DE TRABAJO MAS ARRIBA DEL CARTUCHO DE 1,5 BARES Y UN GASTO MEDIO DE ULTRAFILTRADO DEL ORDEN DE 130 ML/MIN. LA DISOLUCION DE ULTRAFILTRADO SE CONCENTRA A LA MISMA PRESION DE 15 BARES Y A CONTINUACION SE LIOFILIZA. LA MASA MEDIA APARENTE DEL PRODUCTO ESTA COMPRENDIDA ENTRE 2.000 Y 5.000 DALTONS. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTITROMBOTICA E HIPOLIPEMICA.
ES548577A 1984-11-07 1985-11-06 Procedimiento para la fabricacion de nuevos sulfatos de xi- lanos de bajo peso molecular Expired ES8605286A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8417460A FR2572731B1 (fr) 1984-11-07 1984-11-07 Nouveaux sulfates de xylanes de bas poids moleculaires, leur procede de preparation et leur activite antithrombotique et hypolipemiante par voie orale

Publications (2)

Publication Number Publication Date
ES548577A0 ES548577A0 (es) 1986-03-16
ES8605286A1 true ES8605286A1 (es) 1986-03-16

Family

ID=9309636

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548577A Expired ES8605286A1 (es) 1984-11-07 1985-11-06 Procedimiento para la fabricacion de nuevos sulfatos de xi- lanos de bajo peso molecular

Country Status (14)

Country Link
US (1) US4713373A (es)
EP (1) EP0184480A1 (es)
JP (1) JPS61197601A (es)
KR (1) KR860004082A (es)
AU (1) AU4984585A (es)
CA (1) CA1247091A (es)
DK (1) DK510585A (es)
ES (1) ES8605286A1 (es)
FR (1) FR2572731B1 (es)
GR (1) GR852681B (es)
IL (1) IL76886A0 (es)
NZ (1) NZ214094A (es)
PT (1) PT81440B (es)
ZA (1) ZA858532B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820693A (en) * 1986-05-22 1989-04-11 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
US4966890A (en) * 1986-04-04 1990-10-30 Angiogenics, Ltd. Method and composition for arresting angiogenesis and capillary, cell or membrane leakage
WO1988007060A1 (en) * 1987-03-19 1988-09-22 Arthropharm Pty. Limited Anti-inflammatory compounds and compositions
US5668116A (en) * 1987-03-19 1997-09-16 Anthropharm Pty. Limited Anti-inflammatory compounds and compositions
US5484777A (en) * 1989-04-20 1996-01-16 Lange, Iii; Louis G. Pancreatic cholesterol esterase inhibitor
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
US5017565A (en) * 1989-04-20 1991-05-21 Lange Iii Louis G Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase
US5141928B1 (en) * 1989-12-20 1995-11-14 Brujo Inc Ophthalmic medication
US5382570A (en) * 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
US5378829A (en) * 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
US5668274A (en) * 1991-04-23 1997-09-16 Akzo Nobel N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
US5639469A (en) * 1994-06-15 1997-06-17 Minnesota Mining And Manufacturing Company Transmucosal delivery system
US6255295B1 (en) 1996-12-23 2001-07-03 Nutramax Laboratories, Inc. Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
US6797289B2 (en) 1998-02-13 2004-09-28 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US6451771B1 (en) 1999-02-12 2002-09-17 Nutramax Laboratories, Inc. Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals
US20070141181A1 (en) * 1998-02-13 2007-06-21 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
FR2797768B1 (fr) * 1999-09-01 2003-06-13 Ifremer Utilisation d'un polysaccharide sulfate de bas poids moleculaire pour l'obtention d'un medicament actif contre la thrombose vasculaire
WO2008107906A1 (en) * 2007-03-06 2008-09-12 Alembic Limited Process for the preparation of pentosan polysulfate or salts thereof
AU2008255565B2 (en) * 2007-05-31 2013-10-24 Paradigm Biopharmaceuticals Ltd Sulphated xylans for treatment or prophylaxis of respiratory diseases
FI121811B (fi) * 2007-06-01 2011-04-29 Upm Kymmene Corp Uudet dispersiot ja menetelmä niiden valmistamiseksi
WO2009047699A1 (en) * 2007-10-10 2009-04-16 Alembic Limited An improved process for the preparation of an amorphous form of pentosan polysulfate or salts thereof
WO2009087581A1 (en) * 2008-01-04 2009-07-16 Alembic Limited An improved process for the preparation of pentosan polysulfate or salts thereof
AU2008100725B4 (en) * 2008-07-04 2008-10-02 Parnell Technologies Pty Ltd A sulfated polysaccharide compound for clinical use
AU2013202633B2 (en) * 2008-07-04 2015-10-22 Parnell Technologies Pty Ltd A sulfated polysaccharide compound and the preparation and use thereof
WO2012101544A1 (en) 2011-01-29 2012-08-02 Alembic Pharmaceuticals Limited An improved process for the preparation of pentosan polysulfate or salts thereof
WO2012114349A1 (en) 2011-02-23 2012-08-30 Cadila Healthcare Limited An improved process for the preparation of pentosan polysulfate sodium
EP3415153A1 (en) * 2012-01-30 2018-12-19 Baxalta GmbH Non-anticoagulant sulfated or sulfonated polysaccharides
ITMI20130112A1 (it) 2013-01-24 2014-07-25 Chemi Spa Metodo di qualificazione di preparazioni di pentosan polifosfato, sue materie prime e processi di produzione
SG11202001824RA (en) 2016-08-31 2020-04-29 Oji Holdings Corp Production method for acidic xylooligosaccharide, and acidic xylooligosaccharide
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
JP6281659B1 (ja) * 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
CA3065747A1 (en) 2017-05-31 2018-12-06 Oji Holdings Corporation Moisturizing composition comprising pentosan polysulfate
CA3075485A1 (en) * 2017-09-12 2019-03-21 Oji Holdings Corporation Pentosan polysulfate and method for producing pentosan polysulfate
KR102533822B1 (ko) * 2017-12-20 2023-05-17 오지 홀딩스 가부시키가이샤 폴리황산펜토산 및 폴리황산펜토산을 포함하는 의약
EP3666798A1 (de) * 2018-12-11 2020-06-17 Lenzing Aktiengesellschaft Xylan aufweisende zusammensetzung und verfahren zur herstellung einer xylan aufweisenden zusammensetzung
CN115991798B (zh) * 2023-02-16 2024-02-06 南京工业大学 一种生物基半纤维素薄膜材料及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118588C2 (de) * 1981-05-11 1983-07-07 Luitpold-Werk, Chemisch-Pharmazeutische Fabrik, 8000 München Verfahren zur Herstellung eines injizierbaren hochreinen Chondroitinpolysulfates, hiernach erhältliches Produkt und pharmazeutische Zusammensetzung
FR2543145B1 (fr) * 1983-03-24 1986-10-17 Sanofi Sa Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante

Also Published As

Publication number Publication date
IL76886A0 (en) 1986-02-28
CA1247091A (fr) 1988-12-20
AU4984585A (en) 1986-05-15
NZ214094A (en) 1988-01-08
FR2572731B1 (fr) 1987-03-06
KR860004082A (ko) 1986-06-16
ES548577A0 (es) 1986-03-16
JPS61197601A (ja) 1986-09-01
PT81440B (fr) 1987-04-09
DK510585A (da) 1986-05-08
FR2572731A1 (fr) 1986-05-09
DK510585D0 (da) 1985-11-05
US4713373A (en) 1987-12-15
EP0184480A1 (fr) 1986-06-11
ZA858532B (en) 1986-07-30
GR852681B (es) 1986-03-10
PT81440A (fr) 1985-12-01

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