ES8602841A1 - Un procedimiento para preparar un compuesto antibiotico - Google Patents

Un procedimiento para preparar un compuesto antibiotico

Info

Publication number
ES8602841A1
ES8602841A1 ES84534249A ES534249A ES8602841A1 ES 8602841 A1 ES8602841 A1 ES 8602841A1 ES 84534249 A ES84534249 A ES 84534249A ES 534249 A ES534249 A ES 534249A ES 8602841 A1 ES8602841 A1 ES 8602841A1
Authority
ES
Spain
Prior art keywords
aad
aglycone
pseudo
antibiotics
aglycones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES84534249A
Other languages
English (en)
Other versions
ES534249A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES534249A0 publication Critical patent/ES534249A0/es
Publication of ES8602841A1 publication Critical patent/ES8602841A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN COMPUESTO ANTIBIOTICO A PARTIR DE UN COMPLEJO ANTIBIOTICO DE VANCOMICINA. CONSISTE EN HIDROLIZAR UN COMPLEJO ANTIBIOTICO PRODUCIDO POR CULTIVO DE KIBDELOSPORANGIUM ARIDIUM DE FORMULA (I), DONDE R1 ES HIDROGENO O RADICAL MANOSILO Y R2 HIDROGENO O RADICAL GLICOLIPIDO, COMPRENDIENDO LAS OPERACIONES DE DESMANOSILAR POR HIDROLISIS DANDO LUGAR AL COMPUESTO (I) DONDE R1 ES HIDROGENO Y R2 UN RADICAL GLICOLIPIDO Y OPCIONALMENTE DESPUES DE SEPARAR POR HIDROLISIS EL RADICAL GLICOLIPIDO PARA PREPARAR EL COMPUESTO (I) DONDE R1 Y R2 SON HIDROGENO, O COMO VIA ALTERNATIVA, ELIMINAR PRIMERO EL RADICAL GLICOLIPIDO Y DESMANOSILAR DESPUES, REALIZANDOSE EL PROCEDIMIENTO EN AMBOS CASOS EN DISOLVENTE ORGANICO POLAR Y ACIDO DILUIDO. DE APLICACION EN EL TRATAMIENTO DE LA MASTITIS BOVINA Y COMO FACTOR ESTIMULANTE DEL CRECIMIENTO.
ES84534249A 1983-07-13 1984-07-12 Un procedimiento para preparar un compuesto antibiotico Expired ES8602841A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51351483A 1983-07-13 1983-07-13
US06/611,070 US4521335A (en) 1983-07-13 1984-05-17 Aglycone and pseudo-aglycones of the AAD 216 antibiotics

Publications (2)

Publication Number Publication Date
ES534249A0 ES534249A0 (es) 1985-12-01
ES8602841A1 true ES8602841A1 (es) 1985-12-01

Family

ID=27057900

Family Applications (2)

Application Number Title Priority Date Filing Date
ES84534249A Expired ES8602841A1 (es) 1983-07-13 1984-07-12 Un procedimiento para preparar un compuesto antibiotico
ES545185A Expired ES8604231A1 (es) 1983-07-13 1985-07-15 Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES545185A Expired ES8604231A1 (es) 1983-07-13 1985-07-15 Un procedimiento para preparar un compuesto antibiotico de la clase de vancomicina

Country Status (11)

Country Link
US (1) US4521335A (es)
EP (1) EP0132116B1 (es)
JP (1) JP2551550B2 (es)
AU (1) AU565151B2 (es)
CA (1) CA1238316A (es)
DE (1) DE3481307D1 (es)
DK (1) DK162772C (es)
ES (2) ES8602841A1 (es)
GR (1) GR81499B (es)
HK (1) HK50093A (es)
IE (1) IE57869B1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
US4548974A (en) * 1983-07-13 1985-10-22 Smithkline Beckman Corporation Antibiotics produced by Kibdelosporangium aridum shearer
GB8333624D0 (en) * 1983-12-16 1984-01-25 Lepetit Spa Antibiotics l 17054 and l 17392
AU579120B2 (en) * 1983-12-16 1988-11-17 Gruppo Lepetit S.P.A. Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8415092D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Ester derivatives
GB8415093D0 (en) * 1984-06-13 1984-07-18 Lepetit Spa Antibiotic l 17392
ATE72818T1 (de) * 1985-06-20 1992-03-15 Smithkline Beecham Corp Vancomycintyp-antibiotika.
US4694069A (en) * 1985-09-30 1987-09-15 Smithkline Beckman Corporation Kibdelosporangium aridum SK&F-AAD-609
GB8531846D0 (en) * 1985-12-30 1986-02-05 Lepetit Spa Antibiotic a 40926 mannosyl aglycon
GB8608809D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Antibiotic
DK363587A (da) * 1986-07-30 1988-01-31 Smithkline Beckman Corp Antibiotika og fremstilling heraf under anvendelseaf actinomadura parvosata
EP0273727A3 (en) * 1986-12-30 1990-01-17 Smithkline Beecham Corporation Glycosylated glycopeptides
GB8701872D0 (en) * 1987-01-28 1987-03-04 Lepetit Spa N15-alkyl & n15,n15-dialkyl derivatives
US4882313A (en) * 1987-07-31 1989-11-21 Smithkline Beckman Corporation Carboxamide derivatives of glycopeptides
DE68925951T2 (de) * 1988-12-27 1996-07-25 Lepetit Spa Chemisches Verfahren zur Herstellung des Antibiotikums L 17392 (Deglukoteicoplanin) und dessen Salze
AU701463B2 (en) * 1995-07-05 1999-01-28 Sanofi Aventis S.P.A. Purification of dalbaheptide antibiotics by isoelectric focusing
JP4159110B2 (ja) * 1996-04-12 2008-10-01 イーライ・リリー・アンド・カンパニー グリコペプチド化合物
US6037447A (en) * 1996-04-12 2000-03-14 Eli Lilly And Company Glycopeptide compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322343A (en) * 1980-12-18 1982-03-30 Eli Lilly And Company Pseudo-aglycone of actaplanin
RO86375B1 (ro) * 1982-03-24 1985-04-01 Eli Lilly And Company Procedeu pentru prepararea antibioticului a 41030
US4456593A (en) * 1982-06-22 1984-06-26 Abbott Laboratories Ristocetin ψ-aglycone as an antibacterial agent

Also Published As

Publication number Publication date
HK50093A (en) 1993-05-27
US4521335A (en) 1985-06-04
IE57869B1 (en) 1993-05-05
DK340884D0 (da) 1984-07-11
AU3041084A (en) 1985-01-17
ES8604231A1 (es) 1986-01-16
IE841761L (en) 1985-01-13
JPS6069097A (ja) 1985-04-19
ES545185A0 (es) 1986-01-16
GR81499B (es) 1984-12-11
DK340884A (da) 1985-01-14
CA1238316A (en) 1988-06-21
EP0132116A3 (en) 1986-12-10
DE3481307D1 (de) 1990-03-15
EP0132116B1 (en) 1990-02-07
AU565151B2 (en) 1987-09-03
ES534249A0 (es) 1985-12-01
DK162772C (da) 1992-04-27
JP2551550B2 (ja) 1996-11-06
DK162772B (da) 1991-12-09
EP0132116A2 (en) 1985-01-23

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Legal Events

Date Code Title Description
PC2A Transfer of patent

Owner name: PFIZER INC.

FD1A Patent lapsed

Effective date: 20050914