DE3878340D1 - Kristalliner l-carnosin-zink-komplex und dessen herstellung. - Google Patents
Kristalliner l-carnosin-zink-komplex und dessen herstellung.Info
- Publication number
- DE3878340D1 DE3878340D1 DE8888307090T DE3878340T DE3878340D1 DE 3878340 D1 DE3878340 D1 DE 3878340D1 DE 8888307090 T DE8888307090 T DE 8888307090T DE 3878340 T DE3878340 T DE 3878340T DE 3878340 D1 DE3878340 D1 DE 3878340D1
- Authority
- DE
- Germany
- Prior art keywords
- carnosine
- crystalline
- production
- zinc complex
- zinc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- MORUQNQGRSLTCD-FJXQXJEOSA-N (2s)-2-(3-aminopropanoylamino)-3-(1h-imidazol-5-yl)propanoic acid;zinc Chemical compound [Zn].NCCC(=O)N[C@H](C(O)=O)CC1=CNC=N1 MORUQNQGRSLTCD-FJXQXJEOSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62200698A JPH07116160B2 (ja) | 1987-08-10 | 1987-08-10 | 結晶性l−カルノシン亜鉛錯体およびその製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3878340D1 true DE3878340D1 (de) | 1993-03-25 |
DE3878340T2 DE3878340T2 (de) | 1993-05-27 |
Family
ID=16428747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888307090T Expired - Fee Related DE3878340T2 (de) | 1987-08-10 | 1988-08-01 | Kristalliner l-carnosin-zink-komplex und dessen herstellung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4981846A (de) |
EP (1) | EP0303380B1 (de) |
JP (1) | JPH07116160B2 (de) |
KR (1) | KR0128514B1 (de) |
CA (1) | CA1313725C (de) |
DE (1) | DE3878340T2 (de) |
ES (1) | ES2053744T3 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2010057A6 (es) * | 1988-12-26 | 1989-10-16 | Vinas Lab | Procedimiento para la preparacion de un derivado del acido acexamico. |
JP2811353B2 (ja) * | 1990-07-06 | 1998-10-15 | ゼリア新薬工業株式会社 | 炎症性腸疾患予防・治療剤 |
JPH04193022A (ja) * | 1990-11-27 | 1992-07-13 | Takaoka Electric Mfg Co Ltd | 無停電ワンタッチ式点検試験装置 |
US5795859A (en) * | 1991-07-05 | 1998-08-18 | Peptide Technology Limited | Peptide which abrogates TNF and/or LPS toxicity |
WO1993004690A1 (en) * | 1991-09-09 | 1993-03-18 | Peptide Technology Limited | Method for the treatment of the complications and pathology of diabetes |
AU660047B2 (en) * | 1991-09-09 | 1995-06-08 | King's College London | Method for the treatment of the complications and pathology of diabetes |
JP3877807B2 (ja) * | 1996-07-03 | 2007-02-07 | ゼリア新薬工業株式会社 | 口内炎治療・予防剤 |
JPH11322617A (ja) * | 1998-05-07 | 1999-11-24 | Tokiwa Yakuhin Kogyo Kk | チキンまたはカキ抽出物を含有する胃潰瘍予防用または治療用の医薬組成物 |
US8354438B2 (en) * | 2001-08-08 | 2013-01-15 | Michael Chez | Neurological functions |
US20040057974A1 (en) * | 2002-08-06 | 2004-03-25 | Naina Sachdev | Antiwrinkle composition and age reversal complex |
JP4802470B2 (ja) * | 2004-09-27 | 2011-10-26 | ゼリア新薬工業株式会社 | 肝線維化抑制剤 |
PL1976532T3 (pl) | 2006-01-27 | 2016-05-31 | Univ Yale | Szybko działający inhibitor wydzielania kwasu żołądkowego |
US8512761B2 (en) | 2006-01-27 | 2013-08-20 | Yale University | Fast acting inhibitor of gastric acid secretion |
JP4936737B2 (ja) * | 2006-01-31 | 2012-05-23 | 株式会社トクヤマ | 結晶性l−カルノシン亜鉛錯体の製造方法 |
JP4758786B2 (ja) * | 2006-03-01 | 2011-08-31 | 株式会社トクヤマ | アミノ酸類−亜鉛錯体に含まれるアミノ酸類の定量方法 |
JP4880332B2 (ja) * | 2006-03-13 | 2012-02-22 | 株式会社トクヤマ | 結晶性l−カルノシン亜鉛錯体の製造方法 |
EA026964B1 (ru) * | 2010-11-24 | 2017-06-30 | Дьюрект Корпорейшн | Биоразлагаемая композиция для доставки лекарственного средства (варианты) |
KR102286357B1 (ko) * | 2014-02-10 | 2021-08-05 | 가부시끼가이샤 도꾸야마 | 결정성 l-카르노신아연 착체를 함유하는 정제체의 제조 방법 |
SI3551209T1 (sl) | 2016-12-09 | 2021-10-29 | Akston Biosciences Corp | Inzulin-FC fuzije in postopki uporabe |
CN107602661B (zh) * | 2017-08-24 | 2020-03-17 | 烟台万润药业有限公司 | 一种聚普瑞锌的制备方法 |
KR20200050946A (ko) * | 2017-09-05 | 2020-05-12 | 가부시끼가이샤 도꾸야마 | 보호 l-카르노신 유도체, l-카르노신, 및 결정성 l-카르노신 아연착체의 제조 방법 |
KR102191913B1 (ko) | 2019-05-27 | 2020-12-16 | 주식회사 한서켐 | 결정질 폴라프레징크의 제조방법 |
KR102212260B1 (ko) | 2019-06-17 | 2021-02-04 | 주식회사 한서켐 | 수용액을 이용한 결정성 폴라프레징크의 제조방법 |
US11186623B2 (en) | 2019-12-24 | 2021-11-30 | Akston Bioscience Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
US11192930B2 (en) | 2020-04-10 | 2021-12-07 | Askton Bioscences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
CN114149452A (zh) * | 2021-12-08 | 2022-03-08 | 江苏诚信药业有限公司 | 一种l-肌肽锌络合物的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5933720A (ja) * | 1982-08-17 | 1984-02-23 | 富士電機株式会社 | 真空遮断器 |
JPS5933270A (ja) * | 1982-08-19 | 1984-02-23 | Hamari Yakuhin Kogyo Kk | 抗潰瘍剤 |
JPS604172A (ja) * | 1983-06-21 | 1985-01-10 | Hamari Yakuhin Kogyo Kk | カルノシン水酸化亜鉛塩およびその製造法 |
CA1261850A (en) * | 1985-01-19 | 1989-09-26 | Masahiro Takaya | Homocarnosine or acylhomocarnosine salts |
-
1987
- 1987-08-10 JP JP62200698A patent/JPH07116160B2/ja not_active Expired - Lifetime
-
1988
- 1988-07-19 CA CA000572465A patent/CA1313725C/en not_active Expired - Lifetime
- 1988-07-20 US US07/221,749 patent/US4981846A/en not_active Expired - Lifetime
- 1988-08-01 EP EP88307090A patent/EP0303380B1/de not_active Expired - Lifetime
- 1988-08-01 DE DE8888307090T patent/DE3878340T2/de not_active Expired - Fee Related
- 1988-08-01 ES ES88307090T patent/ES2053744T3/es not_active Expired - Lifetime
- 1988-08-09 KR KR1019880010153A patent/KR0128514B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA1313725C (en) | 1993-02-16 |
EP0303380A2 (de) | 1989-02-15 |
KR0128514B1 (ko) | 1998-04-04 |
US4981846A (en) | 1991-01-01 |
EP0303380B1 (de) | 1993-02-10 |
JPS6442471A (en) | 1989-02-14 |
ES2053744T3 (es) | 1994-08-01 |
JPH07116160B2 (ja) | 1995-12-13 |
DE3878340T2 (de) | 1993-05-27 |
KR890003673A (ko) | 1989-04-17 |
EP0303380A3 (en) | 1990-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |