DE3878340D1 - Kristalliner l-carnosin-zink-komplex und dessen herstellung. - Google Patents

Kristalliner l-carnosin-zink-komplex und dessen herstellung.

Info

Publication number
DE3878340D1
DE3878340D1 DE8888307090T DE3878340T DE3878340D1 DE 3878340 D1 DE3878340 D1 DE 3878340D1 DE 8888307090 T DE8888307090 T DE 8888307090T DE 3878340 T DE3878340 T DE 3878340T DE 3878340 D1 DE3878340 D1 DE 3878340D1
Authority
DE
Germany
Prior art keywords
carnosine
crystalline
production
zinc complex
zinc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888307090T
Other languages
English (en)
Other versions
DE3878340T2 (de
Inventor
Takefumi Matsukura
Tamiko Takahashi
Yasuhiro Nishimura
Masahiro Takaya
Hajime Fujimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hamari Chemicals Ltd
Original Assignee
Hamari Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hamari Chemicals Ltd filed Critical Hamari Chemicals Ltd
Publication of DE3878340D1 publication Critical patent/DE3878340D1/de
Application granted granted Critical
Publication of DE3878340T2 publication Critical patent/DE3878340T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/003—Compounds containing elements of Groups 2 or 12 of the Periodic Table without C-Metal linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8888307090T 1987-08-10 1988-08-01 Kristalliner l-carnosin-zink-komplex und dessen herstellung. Expired - Fee Related DE3878340T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62200698A JPH07116160B2 (ja) 1987-08-10 1987-08-10 結晶性ｌ−カルノシン亜鉛錯体およびその製造法

Publications (2)

Publication Number Publication Date
DE3878340D1 true DE3878340D1 (de) 1993-03-25
DE3878340T2 DE3878340T2 (de) 1993-05-27

Family

ID=16428747

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888307090T Expired - Fee Related DE3878340T2 (de) 1987-08-10 1988-08-01 Kristalliner l-carnosin-zink-komplex und dessen herstellung.

Country Status (7)

Country Link
US (1) US4981846A (de)
EP (1) EP0303380B1 (de)
JP (1) JPH07116160B2 (de)
KR (1) KR0128514B1 (de)
CA (1) CA1313725C (de)
DE (1) DE3878340T2 (de)
ES (1) ES2053744T3 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2010057A6 (es) * 1988-12-26 1989-10-16 Vinas Lab Procedimiento para la preparacion de un derivado del acido acexamico.
JP2811353B2 (ja) * 1990-07-06 1998-10-15 ゼリア新薬工業株式会社 炎症性腸疾患予防・治療剤
JPH04193022A (ja) * 1990-11-27 1992-07-13 Takaoka Electric Mfg Co Ltd 無停電ワンタッチ式点検試験装置
US5795859A (en) * 1991-07-05 1998-08-18 Peptide Technology Limited Peptide which abrogates TNF and/or LPS toxicity
WO1993004690A1 (en) * 1991-09-09 1993-03-18 Peptide Technology Limited Method for the treatment of the complications and pathology of diabetes
AU660047B2 (en) * 1991-09-09 1995-06-08 King's College London Method for the treatment of the complications and pathology of diabetes
JP3877807B2 (ja) * 1996-07-03 2007-02-07 ゼリア新薬工業株式会社 口内炎治療・予防剤
JPH11322617A (ja) * 1998-05-07 1999-11-24 Tokiwa Yakuhin Kogyo Kk チキンまたはカキ抽出物を含有する胃潰瘍予防用または治療用の医薬組成物
US8354438B2 (en) * 2001-08-08 2013-01-15 Michael Chez Neurological functions
US20040057974A1 (en) * 2002-08-06 2004-03-25 Naina Sachdev Antiwrinkle composition and age reversal complex
JP4802470B2 (ja) * 2004-09-27 2011-10-26 ゼリア新薬工業株式会社 肝線維化抑制剤
PL1976532T3 (pl) 2006-01-27 2016-05-31 Univ Yale Szybko działający inhibitor wydzielania kwasu żołądkowego
US8512761B2 (en) 2006-01-27 2013-08-20 Yale University Fast acting inhibitor of gastric acid secretion
JP4936737B2 (ja) * 2006-01-31 2012-05-23 株式会社トクヤマ 結晶性ｌ−カルノシン亜鉛錯体の製造方法
JP4758786B2 (ja) * 2006-03-01 2011-08-31 株式会社トクヤマ アミノ酸類−亜鉛錯体に含まれるアミノ酸類の定量方法
JP4880332B2 (ja) * 2006-03-13 2012-02-22 株式会社トクヤマ 結晶性ｌ−カルノシン亜鉛錯体の製造方法
EA026964B1 (ru) * 2010-11-24 2017-06-30 Дьюрект Корпорейшн Биоразлагаемая композиция для доставки лекарственного средства (варианты)
KR102286357B1 (ko) * 2014-02-10 2021-08-05 가부시끼가이샤 도꾸야마 결정성 l-카르노신아연 착체를 함유하는 정제체의 제조 방법
SI3551209T1 (sl) 2016-12-09 2021-10-29 Akston Biosciences Corp Inzulin-FC fuzije in postopki uporabe
CN107602661B (zh) * 2017-08-24 2020-03-17 烟台万润药业有限公司 一种聚普瑞锌的制备方法
KR20200050946A (ko) * 2017-09-05 2020-05-12 가부시끼가이샤 도꾸야마 보호 l-카르노신 유도체, l-카르노신, 및 결정성 l-카르노신 아연착체의 제조 방법
KR102191913B1 (ko) 2019-05-27 2020-12-16 주식회사 한서켐 결정질 폴라프레징크의 제조방법
KR102212260B1 (ko) 2019-06-17 2021-02-04 주식회사 한서켐 수용액을 이용한 결정성 폴라프레징크의 제조방법
US11186623B2 (en) 2019-12-24 2021-11-30 Akston Bioscience Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
US11192930B2 (en) 2020-04-10 2021-12-07 Askton Bioscences Corporation Ultra-long acting insulin-Fc fusion protein and methods of use
CN114149452A (zh) * 2021-12-08 2022-03-08 江苏诚信药业有限公司 一种l-肌肽锌络合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5933720A (ja) * 1982-08-17 1984-02-23 富士電機株式会社 真空遮断器
JPS5933270A (ja) * 1982-08-19 1984-02-23 Hamari Yakuhin Kogyo Kk 抗潰瘍剤
JPS604172A (ja) * 1983-06-21 1985-01-10 Hamari Yakuhin Kogyo Kk カルノシン水酸化亜鉛塩およびその製造法
CA1261850A (en) * 1985-01-19 1989-09-26 Masahiro Takaya Homocarnosine or acylhomocarnosine salts

Also Published As

Publication number Publication date
CA1313725C (en) 1993-02-16
EP0303380A2 (de) 1989-02-15
KR0128514B1 (ko) 1998-04-04
US4981846A (en) 1991-01-01
EP0303380B1 (de) 1993-02-10
JPS6442471A (en) 1989-02-14
ES2053744T3 (es) 1994-08-01
JPH07116160B2 (ja) 1995-12-13
DE3878340T2 (de) 1993-05-27
KR890003673A (ko) 1989-04-17
EP0303380A3 (en) 1990-01-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee