ES8600765A1 - Procedimiento de preparar derivados de penicilina - Google Patents
Procedimiento de preparar derivados de penicilinaInfo
- Publication number
- ES8600765A1 ES8600765A1 ES538020A ES538020A ES8600765A1 ES 8600765 A1 ES8600765 A1 ES 8600765A1 ES 538020 A ES538020 A ES 538020A ES 538020 A ES538020 A ES 538020A ES 8600765 A1 ES8600765 A1 ES 8600765A1
- Authority
- ES
- Spain
- Prior art keywords
- same
- carboxyl group
- preparation
- penicillin derivatives
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002960 penicillins Chemical class 0.000 title abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000003781 beta lactamase inhibitor Substances 0.000 abstract 1
- 229940126813 beta-lactamase inhibitor Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
- 229940126085 β‑Lactamase Inhibitor Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
- C07F7/0814—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring said ring is substituted at a C ring atom by Si
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARAR DERIVADOS DE PENICILINA.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II), EN EL QUE R3 REPRESENTA UN GRUPO PROTECTOR (METILO, ETILO), CON UN DERIVADO DE VINILO DE FORMULA (III), DONDE R6 SIGNIFICA UN GRUPO ACILOXI, PARA OBTENER COMPUESTOS DE FORMULA (I), Y SUS SALES O ESTERES.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57107171A JPS58225091A (ja) | 1982-06-21 | 1982-06-21 | ペニシリン誘導体及びその製造法 |
JP57233967A JPS59118790A (ja) | 1982-12-24 | 1982-12-24 | ペニシリン誘導体 |
JP58021200A JPS59148788A (ja) | 1983-02-10 | 1983-02-10 | ペニシリン誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8600765A1 true ES8600765A1 (es) | 1985-11-01 |
ES538020A0 ES538020A0 (es) | 1985-11-01 |
Family
ID=27283331
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES523701A Granted ES523701A0 (es) | 1982-06-21 | 1983-06-20 | Procedimiento de preparar derivados de penicilina. |
ES538020A Granted ES538020A0 (es) | 1982-06-21 | 1984-11-27 | Procedimiento de preparar derivados de penicilina |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES523701A Granted ES523701A0 (es) | 1982-06-21 | 1983-06-20 | Procedimiento de preparar derivados de penicilina. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0097446B1 (es) |
AU (1) | AU541028B2 (es) |
DE (1) | DE3362277D1 (es) |
ES (2) | ES523701A0 (es) |
NL (1) | NL930140I2 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1239392A (en) * | 1983-10-13 | 1988-07-19 | Shigeru Yamabe | Penicillin derivatives and process for preparing the same |
JPS60214792A (ja) * | 1984-04-06 | 1985-10-28 | Taiho Yakuhin Kogyo Kk | ペナム酸エステル誘導体 |
US4891369A (en) * | 1986-12-03 | 1990-01-02 | Taiho Pharmaceutical Company, Limited | 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof |
JP2603082B2 (ja) * | 1987-09-07 | 1997-04-23 | 大塚化学株式会社 | ペニシラン酸誘導体の製造法 |
US4958020A (en) * | 1989-05-12 | 1990-09-18 | American Cyanamid Company | Process for producing β-lactamase inhibitor |
AU679800B2 (en) * | 1993-11-06 | 1997-07-10 | Taiho Pharmaceutical Co., Ltd. | Crystalline penicillin derivative, and its production and use |
ES2274978T3 (es) | 2002-06-07 | 2007-06-01 | Orchid Chemicals And Pharmaceuticals Limited | Procedimiento para la reparacion de derivados de penam a partir de derivados de cefam. |
US7249826B2 (en) * | 2004-09-23 | 2007-07-31 | Fujifilm Dimatix, Inc. | Soldering a flexible circuit |
US20060173177A1 (en) * | 2005-01-28 | 2006-08-03 | Gego Csaba L | Process for preparation of penam derivatives |
DK2046802T3 (da) * | 2006-07-12 | 2013-09-16 | Allecra Therapeutics Gmbh | 2-substituerede methylpenamderivater |
CN102382123A (zh) * | 2011-03-10 | 2012-03-21 | 海南美好西林生物制药有限公司 | 一种他唑巴坦钠的制备方法 |
CN102952148B (zh) * | 2011-08-26 | 2014-11-05 | 秦引林 | 一种他唑巴坦钠的精制方法 |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
CA2906151A1 (en) | 2013-03-15 | 2014-09-18 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
US20140274997A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Cephalosporin pharmaceutical compositions |
CN103254214B (zh) * | 2013-05-29 | 2015-06-10 | 齐鲁天和惠世制药有限公司 | 一种2β-叠氮甲基青霉烷酸二苯甲酯的制备方法 |
WO2015035376A2 (en) | 2013-09-09 | 2015-03-12 | Calixa Therapeutics, Inc. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6019315B2 (ja) * | 1976-01-23 | 1985-05-15 | 塩野義製薬株式会社 | アゼチジノン化合物 |
EP0013067A1 (en) * | 1978-12-22 | 1980-07-09 | Beecham Group Plc | Bicyclic beta-lactam antibacterial agents, their use in pharmaceutical compositions, processes for their preparation and intermediates for use in such processes |
-
1983
- 1983-06-06 AU AU15403/83A patent/AU541028B2/en not_active Expired
- 1983-06-07 EP EP19830303268 patent/EP0097446B1/en not_active Expired
- 1983-06-07 DE DE8383303268T patent/DE3362277D1/de not_active Expired
- 1983-06-20 ES ES523701A patent/ES523701A0/es active Granted
-
1984
- 1984-11-27 ES ES538020A patent/ES538020A0/es active Granted
-
1993
- 1993-09-23 NL NL930140C patent/NL930140I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
DE3362277D1 (en) | 1986-04-03 |
ES8503686A1 (es) | 1985-03-16 |
ES523701A0 (es) | 1985-03-16 |
ES538020A0 (es) | 1985-11-01 |
NL930140I1 (nl) | 1993-12-01 |
NL930140I2 (nl) | 1998-01-05 |
EP0097446A1 (en) | 1984-01-04 |
AU541028B2 (en) | 1984-12-13 |
AU1540383A (en) | 1984-01-05 |
EP0097446B1 (en) | 1986-02-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8600765A1 (es) | Procedimiento de preparar derivados de penicilina | |
CA1258859A (en) | CARBOSTYRILE DERIVATIVE, AND ITS PREPARATION | |
ES8607287A1 (es) | Un procedimiento para preparar derivados de 1,8-naftiridina | |
MY131501A (en) | Process for the prepration of clavulanic acid | |
HUT52059A (en) | Process for producing pharmaceutical compositions and new quinoline derivatives as a group of active components | |
ES450881A1 (es) | Un procedimiento de preparacion de acidos heteroarilbenzoxe-pin-aceticos y sus derivados. | |
PT83104A (en) | Novel guanidinomethylbenzoic acid derivatives | |
ES8707541A1 (es) | Un procedimiento para la preparacion de derivados de cefalosporina | |
IL113744A0 (en) | 3-Cephem derivatives and their preparation | |
ES8502118A1 (es) | Procedimiento de preparar derivados de penicilina. | |
GR1002384B (el) | Μεθοδος παρασκευης παραγωγων υποκατεστημενου στυρολιου. | |
ES454063A1 (es) | Un procedimiento para la preparacion de nuevos derivados delalcohol bencilico. | |
ES474367A1 (es) | Procedimiento de preparacion de nuevos derivados del benzo- (d)tiazol. | |
MY101993A (en) | Cephalosporin ester derivatives their production and use. | |
ES8303393A1 (es) | Un procedimiento para preparar derivados del acido ascorbico. | |
EP0189916A3 (en) | 3-(pyrrolidinio)methyl-3-cephem derivatives, pharmaceutical composition and process for the production thereof | |
DE3480542D1 (en) | Cephem compounds | |
ES8704163A1 (es) | Un procedimiento para preparar derivados de cefem. | |
GB1263782A (en) | Esters of phenylacetic acids and their production and compositions containing them | |
ES483303A1 (es) | Un procedimiento para la preparacion de derivados de benzo- diacepina | |
ES8305703A1 (es) | Un derivado de 2-benzoilamino-bencilamina. | |
ES8104198A1 (es) | Un procedimiento para la preparacion de un derivado de mo- noamida del acido tereftalico | |
JPS5283393A (en) | Synthesis of novel penicillin derivatives | |
JPS51136698A (en) | Process for preparing new pyridone carboxylic acid derivatives | |
JPS53127490A (en) | Novel nitrogen-containing heterocyclic compound |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20050528 |