ES8505668A1 - Un procedimiento para preparar un derivado de imidazolinona - Google Patents

Un procedimiento para preparar un derivado de imidazolinona

Info

Publication number
ES8505668A1
ES8505668A1 ES531933A ES531933A ES8505668A1 ES 8505668 A1 ES8505668 A1 ES 8505668A1 ES 531933 A ES531933 A ES 531933A ES 531933 A ES531933 A ES 531933A ES 8505668 A1 ES8505668 A1 ES 8505668A1
Authority
ES
Spain
Prior art keywords
alkyl
phenyl
histamine
antagonists
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531933A
Other languages
English (en)
Other versions
ES531933A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of ES8505668A1 publication Critical patent/ES8505668A1/es
Publication of ES531933A0 publication Critical patent/ES531933A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE IMIDAZOLINONA.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN UN DISOLVENTE ORGANICO COMO ETANOL, PIRIDINA Y A UNA TEMPERATURA ENTRE 120 Y 170JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES. SIENDO: R Y R, H, ALQUILO DE C 1 A 6, ARIL-ALQUILO DE C 1 A 6 Y OTROS; R, H O ALQUILO DE C 1 A 6 SUSTITUIDO CON GRUPOS FENILO HIDROXI Y OTROS; R Y R, H, ALQUILO DE C 1 A 6 SUSTITUIDO CON FENILO O FENILO; R, R R N (CH2)NZ-, FURAN-2-ILO Y OTROS; Y, O, S O METILENO; Z PIRIDILO O FENILO; M, 1; N DE 1 A 6 Y P 2, 3 O 4.SE UTILIZAN COMO ANTAGONISTAS H2 DE LA HISTAMINA.
ES531933A 1983-04-27 1984-04-26 Un procedimiento para preparar un derivado de imidazolinona Granted ES531933A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838311443A GB8311443D0 (en) 1983-04-27 1983-04-27 Chemical compounds

Publications (2)

Publication Number Publication Date
ES8505668A1 true ES8505668A1 (es) 1985-06-01
ES531933A0 ES531933A0 (es) 1985-06-01

Family

ID=10541762

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531933A Granted ES531933A0 (es) 1983-04-27 1984-04-26 Un procedimiento para preparar un derivado de imidazolinona

Country Status (17)

Country Link
US (1) US4567176A (es)
EP (1) EP0132914B1 (es)
JP (1) JPS60501207A (es)
KR (1) KR840008330A (es)
AT (1) ATE34978T1 (es)
DE (1) DE3471929D1 (es)
ES (1) ES531933A0 (es)
FI (1) FI845095L (es)
GB (1) GB8311443D0 (es)
GR (1) GR81941B (es)
HU (1) HUT34744A (es)
IL (1) IL71639A0 (es)
NO (1) NO845172L (es)
PT (1) PT78498B (es)
WO (1) WO1984004304A1 (es)
ZA (1) ZA843088B (es)
ZW (1) ZW6784A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
TW221689B (es) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
GB9611046D0 (en) * 1996-05-25 1996-07-31 Wivenhoe Techn Ltd Pharmacological compounds
WO2005097751A2 (en) 2004-03-31 2005-10-20 Janssen Pharmaceutica, N.V. Non-imidazole heterocyclic compounds as histamine h3-receptor ligands
MX2008015365A (es) 2006-05-30 2008-12-16 Janssen Pharmaceutica Nv Compuestos de piridil amida sustituidos como moduladores del receptor h3 de la histamina.
AU2008326561B2 (en) 2007-11-20 2013-12-05 Janssen Pharmaceutica N.V. Cycloalkyloxy-and heterocycloalky-loxypyridine compounds as modulators of the histamine H3 receptor
US20230349922A1 (en) 2020-08-11 2023-11-02 Université De Strasbourg H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968216A (en) * 1969-10-29 1976-07-06 Smith Kline & French Laboratories Limited Method of inhibiting histamine activity with guanidine compounds
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
IN151188B (es) * 1978-02-13 1983-03-05 Smith Kline French Lab
ZA793443B (en) * 1978-07-26 1980-12-31 Glaxo Group Ltd Heterocyclic derivatives
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
GR79384B (es) * 1982-08-20 1984-10-22 Hoechst Uk Ltd

Also Published As

Publication number Publication date
ZA843088B (en) 1985-02-27
EP0132914A3 (en) 1985-12-27
EP0132914A2 (en) 1985-02-13
GB8311443D0 (en) 1983-06-02
PT78498A (en) 1984-05-01
FI845095A0 (fi) 1984-12-21
ZW6784A1 (en) 1985-04-17
FI845095L (fi) 1984-12-21
GR81941B (es) 1984-12-12
NO845172L (no) 1984-12-21
DE3471929D1 (de) 1988-07-14
ATE34978T1 (de) 1988-06-15
US4567176A (en) 1986-01-28
WO1984004304A1 (en) 1984-11-08
IL71639A0 (en) 1984-07-31
KR840008330A (ko) 1984-12-14
EP0132914B1 (en) 1988-06-08
JPS60501207A (ja) 1985-08-01
ES531933A0 (es) 1985-06-01
PT78498B (en) 1986-06-02
HUT34744A (en) 1985-04-28

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