ES8505668A1 - Un procedimiento para preparar un derivado de imidazolinona - Google Patents
Un procedimiento para preparar un derivado de imidazolinonaInfo
- Publication number
- ES8505668A1 ES8505668A1 ES531933A ES531933A ES8505668A1 ES 8505668 A1 ES8505668 A1 ES 8505668A1 ES 531933 A ES531933 A ES 531933A ES 531933 A ES531933 A ES 531933A ES 8505668 A1 ES8505668 A1 ES 8505668A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- phenyl
- histamine
- antagonists
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/86—Oxygen and sulfur atoms, e.g. thiohydantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UN DERIVADO DE IMIDAZOLINONA.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN UN DISOLVENTE ORGANICO COMO ETANOL, PIRIDINA Y A UNA TEMPERATURA ENTRE 120 Y 170JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES. SIENDO: R Y R, H, ALQUILO DE C 1 A 6, ARIL-ALQUILO DE C 1 A 6 Y OTROS; R, H O ALQUILO DE C 1 A 6 SUSTITUIDO CON GRUPOS FENILO HIDROXI Y OTROS; R Y R, H, ALQUILO DE C 1 A 6 SUSTITUIDO CON FENILO O FENILO; R, R R N (CH2)NZ-, FURAN-2-ILO Y OTROS; Y, O, S O METILENO; Z PIRIDILO O FENILO; M, 1; N DE 1 A 6 Y P 2, 3 O 4.SE UTILIZAN COMO ANTAGONISTAS H2 DE LA HISTAMINA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838311443A GB8311443D0 (en) | 1983-04-27 | 1983-04-27 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8505668A1 true ES8505668A1 (es) | 1985-06-01 |
ES531933A0 ES531933A0 (es) | 1985-06-01 |
Family
ID=10541762
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES531933A Granted ES531933A0 (es) | 1983-04-27 | 1984-04-26 | Un procedimiento para preparar un derivado de imidazolinona |
Country Status (17)
Country | Link |
---|---|
US (1) | US4567176A (es) |
EP (1) | EP0132914B1 (es) |
JP (1) | JPS60501207A (es) |
KR (1) | KR840008330A (es) |
AT (1) | ATE34978T1 (es) |
DE (1) | DE3471929D1 (es) |
ES (1) | ES531933A0 (es) |
FI (1) | FI845095L (es) |
GB (1) | GB8311443D0 (es) |
GR (1) | GR81941B (es) |
HU (1) | HUT34744A (es) |
IL (1) | IL71639A0 (es) |
NO (1) | NO845172L (es) |
PT (1) | PT78498B (es) |
WO (1) | WO1984004304A1 (es) |
ZA (1) | ZA843088B (es) |
ZW (1) | ZW6784A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8417194D0 (en) * | 1984-07-05 | 1984-08-08 | Boots Co Plc | Therapeutic agents |
TW221689B (es) * | 1991-08-27 | 1994-03-11 | Otsuka Pharma Co Ltd | |
GB9611046D0 (en) * | 1996-05-25 | 1996-07-31 | Wivenhoe Techn Ltd | Pharmacological compounds |
WO2005097751A2 (en) | 2004-03-31 | 2005-10-20 | Janssen Pharmaceutica, N.V. | Non-imidazole heterocyclic compounds as histamine h3-receptor ligands |
MX2008015365A (es) | 2006-05-30 | 2008-12-16 | Janssen Pharmaceutica Nv | Compuestos de piridil amida sustituidos como moduladores del receptor h3 de la histamina. |
AU2008326561B2 (en) | 2007-11-20 | 2013-12-05 | Janssen Pharmaceutica N.V. | Cycloalkyloxy-and heterocycloalky-loxypyridine compounds as modulators of the histamine H3 receptor |
US20230349922A1 (en) | 2020-08-11 | 2023-11-02 | Université De Strasbourg | H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3968216A (en) * | 1969-10-29 | 1976-07-06 | Smith Kline & French Laboratories Limited | Method of inhibiting histamine activity with guanidine compounds |
GB1419994A (en) * | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
IN151188B (es) * | 1978-02-13 | 1983-03-05 | Smith Kline French Lab | |
ZA793443B (en) * | 1978-07-26 | 1980-12-31 | Glaxo Group Ltd | Heterocyclic derivatives |
ZW21281A1 (en) * | 1980-10-01 | 1981-11-18 | Smith Kline French Lab | Amine derivatives |
GR79384B (es) * | 1982-08-20 | 1984-10-22 | Hoechst Uk Ltd |
-
1983
- 1983-04-27 GB GB838311443A patent/GB8311443D0/en active Pending
-
1984
- 1984-04-13 DE DE8484302550T patent/DE3471929D1/de not_active Expired
- 1984-04-13 JP JP59501699A patent/JPS60501207A/ja active Pending
- 1984-04-13 HU HU842253A patent/HUT34744A/hu unknown
- 1984-04-13 EP EP84302550A patent/EP0132914B1/en not_active Expired
- 1984-04-13 WO PCT/GB1984/000127 patent/WO1984004304A1/en active Application Filing
- 1984-04-13 AT AT84302550T patent/ATE34978T1/de active
- 1984-04-18 US US06/601,527 patent/US4567176A/en not_active Expired - Fee Related
- 1984-04-24 GR GR74486A patent/GR81941B/el unknown
- 1984-04-25 IL IL71639A patent/IL71639A0/xx unknown
- 1984-04-26 KR KR1019840002229A patent/KR840008330A/ko not_active Application Discontinuation
- 1984-04-26 ZA ZA843088A patent/ZA843088B/xx unknown
- 1984-04-26 ES ES531933A patent/ES531933A0/es active Granted
- 1984-04-26 PT PT78498A patent/PT78498B/pt unknown
- 1984-04-26 ZW ZW67/84A patent/ZW6784A1/xx unknown
- 1984-12-21 NO NO845172A patent/NO845172L/no unknown
- 1984-12-21 FI FI845095A patent/FI845095L/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA843088B (en) | 1985-02-27 |
EP0132914A3 (en) | 1985-12-27 |
EP0132914A2 (en) | 1985-02-13 |
GB8311443D0 (en) | 1983-06-02 |
PT78498A (en) | 1984-05-01 |
FI845095A0 (fi) | 1984-12-21 |
ZW6784A1 (en) | 1985-04-17 |
FI845095L (fi) | 1984-12-21 |
GR81941B (es) | 1984-12-12 |
NO845172L (no) | 1984-12-21 |
DE3471929D1 (de) | 1988-07-14 |
ATE34978T1 (de) | 1988-06-15 |
US4567176A (en) | 1986-01-28 |
WO1984004304A1 (en) | 1984-11-08 |
IL71639A0 (en) | 1984-07-31 |
KR840008330A (ko) | 1984-12-14 |
EP0132914B1 (en) | 1988-06-08 |
JPS60501207A (ja) | 1985-08-01 |
ES531933A0 (es) | 1985-06-01 |
PT78498B (en) | 1986-06-02 |
HUT34744A (en) | 1985-04-28 |
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