ES8502979A1 - Procedimiento para preparar (2-((aminopiridinil)-amino)-fenil)-arilmetanonas y analogos - Google Patents
Procedimiento para preparar (2-((aminopiridinil)-amino)-fenil)-arilmetanonas y analogosInfo
- Publication number
- ES8502979A1 ES8502979A1 ES524877A ES524877A ES8502979A1 ES 8502979 A1 ES8502979 A1 ES 8502979A1 ES 524877 A ES524877 A ES 524877A ES 524877 A ES524877 A ES 524877A ES 8502979 A1 ES8502979 A1 ES 8502979A1
- Authority
- ES
- Spain
- Prior art keywords
- arylmethanones
- phenyl
- amino
- nitropyridinyl
- benzodiazepines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Combination Of More Than One Step In Electrophotography (AREA)
- Paper (AREA)
- Luminescent Compositions (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR 2-(AMINOPIRIDINIL)-AMINO-FENIL-ARILMETANONAS Y ANALOGOS.COMPRENDE: 1) HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UNA HALONITROPIRIDINA DE FORMULA (III) PARA OBTENER UN COMPUESTO DE FORMULA (IV); 2) HACER REACCIONAR EL COMPUESTO OBTENIDO EN LA FASE ANTERIOR DONDE R ES H, CON UN REACTIVO DE FORMULA (V) PARA PRODUCIR UN COMPUESTO DE FORMULA (I), DONDE R SE ELIGE ENTRE EL GRUPO QUE CONSTA DE H O -ALC-Q; Q SE ELIGE DEL GRUPO QUE CONSTA DE H, NRR O HALOGENO; R Y R SE ELIGEN ENTRE UN GRUPO QUE CONSTA DE ALCOHILO INFERIOR, C(O)-O- ALCOHILO INFERIOR, O CONSIDERADOS CONJUNTAMENTE CON EL ATOMO DE NITROGENO ADYACENTE PUEDEN FORMAR UN RESTO HETEROCICLICO; ALC ES UNA CADENA DE HIDROCARBURO; Y AR SE ELIGE ENTRE EL GRUPO QUE CONSTA DE 2 O 3-TIENILO, 2, 3 O 4 PIRIDINILO Y OTROS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/431,997 US4480100A (en) | 1982-09-30 | 1982-09-30 | [2-[(Nitropyridinyl)amino]phenyl]arymethanones |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8502979A1 true ES8502979A1 (es) | 1985-02-01 |
ES524877A0 ES524877A0 (es) | 1985-02-01 |
Family
ID=23714311
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES518377A Granted ES518377A0 (es) | 1982-09-30 | 1982-12-20 | Procedimiento para la preparacion de pirido (1,4) benzodiazepinas. |
ES524877A Granted ES524877A0 (es) | 1982-09-30 | 1983-08-11 | Procedimiento para preparar (2-((aminopiridinil)-amino)-fenil)-arilmetanonas y analogos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES518377A Granted ES518377A0 (es) | 1982-09-30 | 1982-12-20 | Procedimiento para la preparacion de pirido (1,4) benzodiazepinas. |
Country Status (24)
Country | Link |
---|---|
US (1) | US4480100A (es) |
EP (1) | EP0107261B1 (es) |
JP (1) | JPS5970669A (es) |
KR (1) | KR870000279B1 (es) |
AT (1) | ATE37359T1 (es) |
AU (1) | AU550964B2 (es) |
CA (1) | CA1194869A (es) |
DE (1) | DE3378047D1 (es) |
DK (1) | DK547682A (es) |
EG (1) | EG16124A (es) |
ES (2) | ES518377A0 (es) |
FI (1) | FI77032C (es) |
GR (1) | GR77821B (es) |
HU (2) | HU190448B (es) |
IE (1) | IE54331B1 (es) |
IL (1) | IL67499A (es) |
IN (1) | IN156482B (es) |
NO (1) | NO160366C (es) |
NZ (1) | NZ202799A (es) |
PH (1) | PH20696A (es) |
PL (2) | PL145081B1 (es) |
PT (1) | PT76094B (es) |
YU (1) | YU125083A (es) |
ZA (1) | ZA829154B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668675A (en) * | 1981-09-24 | 1987-05-26 | A. H. Robins Company, Incorporated | 2-[(amino-pyridinyl)amine]phenyl]aryl methanones, their thioxomethyl, ketal or thioketal analogs |
US4560510A (en) * | 1984-04-06 | 1985-12-24 | A. H. Robins Company, Incorporated | Process and intermediates for the preparation of aryl substituted pyrido[1,4]benzodiazepines |
US4628100A (en) * | 1984-04-06 | 1986-12-09 | A. H. Robins Company, Incorporated | Intermediates for the preparation of aryl substituted pyrido[1,4]benzodiazepines |
US4749788A (en) * | 1987-04-13 | 1988-06-07 | A. H. Robins Company, Incorporated | Process for the preparation of aryl-pyrido(1,4) benzodiazepines |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT327200B (de) * | 1972-09-06 | 1976-01-26 | Degussa | Verfahren zur herstellung von neuen aza-10,11-dihydro-5h-dibenzo (b,e)-(1,4) diazepinen sowie deren salzen |
SE7605398L (sv) * | 1975-05-28 | 1976-11-29 | Merck & Co Inc | 3h-1,2,3-trizol(4,5-b)pyridiner |
-
1982
- 1982-09-30 US US06/431,997 patent/US4480100A/en not_active Expired - Lifetime
- 1982-12-07 NO NO824116A patent/NO160366C/no unknown
- 1982-12-09 DK DK547682A patent/DK547682A/da not_active Application Discontinuation
- 1982-12-10 FI FI824248A patent/FI77032C/fi not_active IP Right Cessation
- 1982-12-13 ZA ZA829154A patent/ZA829154B/xx unknown
- 1982-12-14 IN IN1443/CAL/82A patent/IN156482B/en unknown
- 1982-12-14 NZ NZ202799A patent/NZ202799A/en unknown
- 1982-12-14 PH PH28277A patent/PH20696A/en unknown
- 1982-12-16 IL IL67499A patent/IL67499A/xx unknown
- 1982-12-17 IE IE3009/82A patent/IE54331B1/en unknown
- 1982-12-20 ES ES518377A patent/ES518377A0/es active Granted
- 1982-12-22 AU AU91779/82A patent/AU550964B2/en not_active Ceased
- 1982-12-29 GR GR70180A patent/GR77821B/el unknown
- 1982-12-31 KR KR8205903A patent/KR870000279B1/ko active
-
1983
- 1983-01-07 DE DE8383300097T patent/DE3378047D1/de not_active Expired
- 1983-01-07 EP EP83300097A patent/EP0107261B1/en not_active Expired
- 1983-01-07 AT AT83300097T patent/ATE37359T1/de not_active IP Right Cessation
- 1983-01-14 PT PT76094A patent/PT76094B/pt unknown
- 1983-01-15 EG EG28/83A patent/EG16124A/xx active
- 1983-02-08 JP JP58019545A patent/JPS5970669A/ja active Pending
- 1983-05-12 HU HU831646A patent/HU190448B/hu not_active IP Right Cessation
- 1983-05-12 HU HU86500A patent/HU193360B/hu not_active IP Right Cessation
- 1983-05-13 PL PL1983252857A patent/PL145081B1/pl unknown
- 1983-05-13 PL PL1983241970A patent/PL139382B1/pl unknown
- 1983-05-30 CA CA000429140A patent/CA1194869A/en not_active Expired
- 1983-06-06 YU YU01250/83A patent/YU125083A/xx unknown
- 1983-08-11 ES ES524877A patent/ES524877A0/es active Granted
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