ES8502696A1 - Procedimiento para preparar derivados de 4-oxo-tiazolidin-2-iliden-acetamida - Google Patents

Procedimiento para preparar derivados de 4-oxo-tiazolidin-2-iliden-acetamida

Info

Publication number
ES8502696A1
ES8502696A1 ES532331A ES532331A ES8502696A1 ES 8502696 A1 ES8502696 A1 ES 8502696A1 ES 532331 A ES532331 A ES 532331A ES 532331 A ES532331 A ES 532331A ES 8502696 A1 ES8502696 A1 ES 8502696A1
Authority
ES
Spain
Prior art keywords
preparation
nervous system
central nervous
yliden
thiazolidin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532331A
Other languages
English (en)
Other versions
ES532331A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Goedecke GmbH
Original Assignee
Goedecke GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke GmbH filed Critical Goedecke GmbH
Publication of ES532331A0 publication Critical patent/ES532331A0/es
Publication of ES8502696A1 publication Critical patent/ES8502696A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 4-OXO-TIAZOLIDIN-2-ILIDENACETAMIDA, DE FORMULA (I), EN LA QUE X ES UN ENLACE O UN ALQUILENO C1-4, Y R-R PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN ESTER DE ACIDO TIOGLICOLICO DE FORMULA (III), EN LAS QUE R ES ALQUILENO INFERIOR C1-5, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I).ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA UNA TERAPIA ANTIEPILEPTICA.
ES532331A 1983-05-10 1984-05-09 Procedimiento para preparar derivados de 4-oxo-tiazolidin-2-iliden-acetamida Expired ES8502696A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3317000A DE3317000C2 (de) 1983-05-10 1983-05-10 4-Oxo-thiazolidin-2-yliden-acetamid-derivate, Verfahren zu deren Herstellung und deren Verwendung bei der Bekämpfung von durch das Zentralnervensystem bedingten Konvulsionen

Publications (2)

Publication Number Publication Date
ES532331A0 ES532331A0 (es) 1985-01-16
ES8502696A1 true ES8502696A1 (es) 1985-01-16

Family

ID=6198604

Family Applications (2)

Application Number Title Priority Date Filing Date
ES532322A Granted ES532322A0 (es) 1983-05-10 1984-05-09 Procedimiento para preparar derivados de 4-oxo-tiazolidin-2-iliden-acetamida.
ES532331A Expired ES8502696A1 (es) 1983-05-10 1984-05-09 Procedimiento para preparar derivados de 4-oxo-tiazolidin-2-iliden-acetamida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES532322A Granted ES532322A0 (es) 1983-05-10 1984-05-09 Procedimiento para preparar derivados de 4-oxo-tiazolidin-2-iliden-acetamida.

Country Status (19)

Country Link
US (1) US4563471A (es)
EP (1) EP0124911B1 (es)
JP (1) JPS59206372A (es)
AT (1) ATE65778T1 (es)
AU (1) AU565799B2 (es)
BG (2) BG40143A3 (es)
CA (1) CA1237436A (es)
CS (1) CS244814B2 (es)
DD (1) DD224319A5 (es)
DE (2) DE3317000C2 (es)
DK (1) DK162048C (es)
ES (2) ES532322A0 (es)
GR (1) GR82086B (es)
HU (1) HU190566B (es)
IE (1) IE57372B1 (es)
PL (2) PL142398B1 (es)
SU (2) SU1251803A3 (es)
YU (2) YU45183B (es)
ZA (1) ZA843489B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0269024A3 (en) * 1986-11-21 1990-05-09 Godecke Aktiengesellschaft Use of 3-methyl-4-oxothiazolidin-2-ylidene-acetamide derivatives in the treatment of aids
EP0494405B2 (en) * 1991-01-10 2000-04-19 Transcend Therapeutics, Inc. Use of L-2-oxo thiazolidine-4-carboxylate for the treatment of pulmonary diseases
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
US6133299A (en) * 1993-02-25 2000-10-17 Warner-Lambert Company Methods for treating neurodegenerative diseases and disorders using N-(2,6-disubstituted aromatic)-N'-pyridinyl ureas and other anticonvulsant compounds
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
KR100329808B1 (ko) * 2000-01-14 2002-03-25 박호군 2-펜아실리덴-3,5-알킬치환된-1,3-티아졸리딘-4-온의 효율적 제조 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1150985B (de) * 1961-03-06 1963-07-04 Warner Lambert Pharmaceutical Verfahren zur Herstellung von Thiazolidin-4-on-Derivaten
FR2726M (fr) * 1962-12-04 1964-08-17 Warner Lambert Pharmaceutical Amides de thiazolidinones substituées.
DE2423725C2 (de) * 1974-05-16 1982-12-30 Gödecke AG, 1000 Berlin 5-Phenyl-4-oxo-Delta 2,ALPHA-thiazolidinessigsäureester

Also Published As

Publication number Publication date
DE3317000C2 (de) 1986-09-25
SU1272985A3 (ru) 1986-11-23
YU79284A (es) 1986-10-31
GR82086B (es) 1984-12-13
DK229984D0 (da) 1984-05-09
AU565799B2 (en) 1987-10-01
CA1237436A (en) 1988-05-31
DD224319A5 (de) 1985-07-03
DK162048B (da) 1991-09-09
ES8502430A1 (es) 1985-01-01
IE57372B1 (en) 1992-08-12
SU1251803A3 (ru) 1986-08-15
HUT34174A (en) 1985-02-28
BG40143A3 (en) 1986-10-15
PL142365B1 (en) 1987-10-31
JPS59206372A (ja) 1984-11-22
EP0124911B1 (de) 1991-07-31
HU190566B (en) 1986-09-29
IE841150L (en) 1984-11-10
BG41129A3 (en) 1987-04-15
PL252100A1 (en) 1985-11-05
YU45183B (en) 1992-05-28
ATE65778T1 (de) 1991-08-15
DK162048C (da) 1992-02-10
EP0124911A3 (en) 1987-02-04
YU63586A (en) 1986-10-31
EP0124911A2 (de) 1984-11-14
ES532331A0 (es) 1985-01-16
DE3484859D1 (de) 1991-09-05
DE3317000A1 (de) 1984-11-15
DK229984A (da) 1984-11-11
AU2788984A (en) 1984-11-15
ZA843489B (en) 1984-12-24
PL247581A1 (en) 1985-07-16
US4563471A (en) 1986-01-07
CS244814B2 (en) 1986-08-14
PL142398B1 (en) 1987-10-31
JPS6316386B2 (es) 1988-04-08
ES532322A0 (es) 1985-01-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519