ES8800198A1 - Procedimiento para preparar derivados de acidos aziridin-2- carboxilicos substituidos en n - Google Patents
Procedimiento para preparar derivados de acidos aziridin-2- carboxilicos substituidos en nInfo
- Publication number
- ES8800198A1 ES8800198A1 ES550285A ES550285A ES8800198A1 ES 8800198 A1 ES8800198 A1 ES 8800198A1 ES 550285 A ES550285 A ES 550285A ES 550285 A ES550285 A ES 550285A ES 8800198 A1 ES8800198 A1 ES 8800198A1
- Authority
- ES
- Spain
- Prior art keywords
- carboxylic acid
- acid derivatives
- substances
- preparation
- well
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyridine Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE ACIDOS AZIRIDIN-2-CARBOXILICOS SUSTITUIDOS EN N. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA (III), EN DIOXANO, ENTRE 0 Y 80GC Y DURANTE 3 HORAS A 10 DIAS, PARA OBTENER UN COMPUESTO DE FORMULA (I), SUS SALES Y N-OXIDOS. SIENDO: L, H; HAL Y HAL2, CL O BR; R1, HIDROXI O ALCOXI; R2, HIDROXIMETILO, CARBOXILO Y OTROS; Y X, NITRILO, CARBOXILO Y OTROS. SE UTILIZAN PARA TRATAR LA ARTRITIS REUMATOIDE Y COMBATIR ENFERMEDADES QUE DEBILITAN EL SISTEMA DE INMUNIDAD. *FORMULA*
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843446713 DE3446713A1 (de) | 1984-12-21 | 1984-12-21 | N-substituierte aziridin-2-carbonsaeurederivate, verfahren zu deren herstellung sowie diese substanzen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8800198A1 true ES8800198A1 (es) | 1987-11-01 |
| ES550285A0 ES550285A0 (es) | 1987-11-01 |
Family
ID=6253432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES550285A Expired ES8800198A1 (es) | 1984-12-21 | 1985-12-20 | Procedimiento para preparar derivados de acidos aziridin-2- carboxilicos substituidos en n |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4826858A (es) |
| EP (1) | EP0186049B1 (es) |
| JP (1) | JPS61152678A (es) |
| CN (1) | CN85108698B (es) |
| AT (1) | ATE54315T1 (es) |
| AU (2) | AU578335B2 (es) |
| CS (1) | CS256395B2 (es) |
| DD (1) | DD246299A5 (es) |
| DE (2) | DE3446713A1 (es) |
| DK (1) | DK591685A (es) |
| ES (1) | ES8800198A1 (es) |
| FI (1) | FI854985A (es) |
| GR (1) | GR853057B (es) |
| HU (1) | HU194869B (es) |
| IL (1) | IL77357A (es) |
| NO (1) | NO855210L (es) |
| NZ (1) | NZ214596A (es) |
| PH (1) | PH23039A (es) |
| PL (1) | PL148867B1 (es) |
| PT (1) | PT81702B (es) |
| SU (1) | SU1431676A3 (es) |
| YU (1) | YU199985A (es) |
| ZA (1) | ZA859592B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100738229B1 (ko) * | 2001-12-31 | 2007-07-12 | 한국화학연구원 | 신규한 피롤리디닐피리딘 유도체 |
| CA2547600A1 (en) * | 2003-12-12 | 2005-06-30 | Syngenta Participations Ag | Novel herbicides |
| AU2009259493A1 (en) | 2008-06-16 | 2009-12-23 | F. Hoffmann-La Roche Ag | Pyrrolidine derivatives as NK2 receptor antagonists |
| CN105272896A (zh) * | 2015-10-19 | 2016-01-27 | 山东国润生物医药有限公司 | (（2s）-2-氮丙啶基)二苯基甲醇的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2833986A1 (de) * | 1978-08-03 | 1980-02-21 | Boehringer Mannheim Gmbh | Immunstimulierende n-substituierte aziridin-2-carbonsaeurederivate, verfahren zu ihrer herstellung sowie arzneimittel, die diese substanzen enthalten |
| DE3211254A1 (de) * | 1982-03-26 | 1983-09-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zum nachweis des vorliegens einer allergie und zum spezifischen nachweis des fuer die allergie verantwortlichen allergens |
-
1984
- 1984-12-21 DE DE19843446713 patent/DE3446713A1/de not_active Withdrawn
-
1985
- 1985-12-11 AT AT85115785T patent/ATE54315T1/de not_active IP Right Cessation
- 1985-12-11 EP EP85115785A patent/EP0186049B1/de not_active Expired - Lifetime
- 1985-12-11 DE DE8585115785T patent/DE3578563D1/de not_active Expired - Lifetime
- 1985-12-16 FI FI854985A patent/FI854985A/fi not_active Application Discontinuation
- 1985-12-16 AU AU51265/85A patent/AU578335B2/en not_active Ceased
- 1985-12-16 DD DD85284394A patent/DD246299A5/de unknown
- 1985-12-16 PH PH33180A patent/PH23039A/en unknown
- 1985-12-16 IL IL77357A patent/IL77357A/xx unknown
- 1985-12-17 ZA ZA859592A patent/ZA859592B/xx unknown
- 1985-12-17 JP JP60282177A patent/JPS61152678A/ja active Pending
- 1985-12-17 NZ NZ214596A patent/NZ214596A/xx unknown
- 1985-12-18 GR GR853057A patent/GR853057B/el unknown
- 1985-12-18 PT PT81702A patent/PT81702B/pt unknown
- 1985-12-18 DK DK591685A patent/DK591685A/da not_active Application Discontinuation
- 1985-12-19 PL PL1985256941A patent/PL148867B1/pl unknown
- 1985-12-19 YU YU01999/85A patent/YU199985A/xx unknown
- 1985-12-19 CS CS859547A patent/CS256395B2/cs unknown
- 1985-12-20 SU SU853991691A patent/SU1431676A3/ru active
- 1985-12-20 NO NO855210A patent/NO855210L/no unknown
- 1985-12-20 HU HU854938A patent/HU194869B/hu unknown
- 1985-12-20 ES ES550285A patent/ES8800198A1/es not_active Expired
- 1985-12-21 CN CN85108698A patent/CN85108698B/zh not_active Expired
-
1987
- 1987-11-25 US US07/125,353 patent/US4826858A/en not_active Expired - Fee Related
-
1990
- 1990-02-01 AU AU49015/90A patent/AU625355B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ZA859592B (en) | 1986-09-24 |
| JPS61152678A (ja) | 1986-07-11 |
| DE3578563D1 (de) | 1990-08-09 |
| DK591685D0 (da) | 1985-12-18 |
| FI854985A (fi) | 1986-06-22 |
| PT81702A (de) | 1986-01-02 |
| CS954785A2 (en) | 1987-08-13 |
| FI854985A0 (fi) | 1985-12-16 |
| AU4901590A (en) | 1990-08-02 |
| CN85108698A (zh) | 1986-07-23 |
| CN85108698B (zh) | 1988-09-07 |
| ES550285A0 (es) | 1987-11-01 |
| GR853057B (es) | 1986-04-15 |
| IL77357A (en) | 1989-08-15 |
| SU1431676A3 (ru) | 1988-10-15 |
| ATE54315T1 (de) | 1990-07-15 |
| CS256395B2 (en) | 1988-04-15 |
| YU199985A (en) | 1987-12-31 |
| PL148867B1 (en) | 1989-12-30 |
| EP0186049A1 (de) | 1986-07-02 |
| AU5126585A (en) | 1986-06-26 |
| US4826858A (en) | 1989-05-02 |
| NZ214596A (en) | 1988-10-28 |
| EP0186049B1 (de) | 1990-07-04 |
| DE3446713A1 (de) | 1986-06-26 |
| PH23039A (en) | 1989-03-10 |
| PT81702B (de) | 1987-08-10 |
| DD246299A5 (de) | 1987-06-03 |
| AU625355B2 (en) | 1992-07-09 |
| HU194869B (en) | 1988-03-28 |
| HUT40107A (en) | 1986-11-28 |
| AU578335B2 (en) | 1988-10-20 |
| DK591685A (da) | 1986-06-22 |
| PL256941A1 (en) | 1986-10-07 |
| NO855210L (no) | 1986-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3072122D1 (en) | 7-acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation | |
| TW272195B (es) | ||
| MY103850A (en) | Phenol substituted gem-diphosphonate derivatives, process for their preparation and pharmaceutical compositions containing them. | |
| HUT43843A (en) | Process for production of derivatives of benzimidasole and medical compounds containing thereof | |
| DE3571982D1 (en) | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | |
| YU211087A (en) | Process for obtaining new n-substituted benzimidazolic derivatives | |
| IL94433A0 (en) | Aminophenol derivatives,their preparation and pharmaceutical compositions containing them | |
| IL59425A (en) | Pharmaceutical compositions comprising n-substituted aziridine-2-carboxylic acid derivatives,certain such compounds and their preparation | |
| JO1406B1 (en) | Chemical compounds | |
| PT84923A (en) | Process for the preparation of 1-(hydroxystyrul)-5h-2,3-benzodiapezine derivatives and pharmaceutical compositions containing the same | |
| ES479059A1 (es) | Procedimiento para preparar derivados del naftaleno. | |
| IL57939A (en) | Pharmaceutical compositions containing n-substituted aziridine-2-carboxylic acid derivatives,some such novel compounds and processes for the preparation of said n-substituted aziridine-2-carboxylic acid derivatives | |
| ES8800198A1 (es) | Procedimiento para preparar derivados de acidos aziridin-2- carboxilicos substituidos en n | |
| DE2860777D1 (en) | N-substituted 2-hydrazono-propionic acid derivatives, process for their preparation and pharmaceutical compositions containing them | |
| DE3372772D1 (en) | Quinazolinone derivatives, process for their preparation and their use in medicaments | |
| EP0280627A3 (en) | Derivatives of n-substituted alpha-mercaptomethyl-benzene-propanamide, process for their preparation, their use as medicines and compositions containing them | |
| ES8704148A1 (es) | Un procedimiento para preparar derivados de antraciclina |