ES8502439A1 - Un metodo de preparar una forma solida, estable y soluble en agua de 3-desazaguanina - Google Patents

Un metodo de preparar una forma solida, estable y soluble en agua de 3-desazaguanina

Info

Publication number
ES8502439A1
ES8502439A1 ES525010A ES525010A ES8502439A1 ES 8502439 A1 ES8502439 A1 ES 8502439A1 ES 525010 A ES525010 A ES 525010A ES 525010 A ES525010 A ES 525010A ES 8502439 A1 ES8502439 A1 ES 8502439A1
Authority
ES
Spain
Prior art keywords
deazaguanine
sulphonic acid
acid salts
salts
imidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525010A
Other languages
English (en)
Other versions
ES525010A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES525010A0 publication Critical patent/ES525010A0/es
Publication of ES8502439A1 publication Critical patent/ES8502439A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

METODO PARA PREPARAR UNA FORMA SOLIDA, ESTABLE Y SOLUBLE EN AGUA DE 3-DESAZAGUANINA.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE HACE REACCIONAR EN UN DISOLVENTE ADECUADO, CANTIDADES ESENCIALMENTE EQUIVALENTES DE 3-DESAZAGUANINA BASE Y UN ACIDO SULFONICO DE FORMULA: RSO3H, PARA FORMAR UNA SAL DE FORMULA ESTRUCTURAL (I); SEGUNDA, SE SEPARA EL DISOLVENTE PARA FORMAR UN RESIDUO SOLIDO; Y POR ULTIMO, SE PURIFICA ADICIONALMENTE EL RESIDUO SOLIDO MEDIANTE RECRISTALIZACION.
ES525010A 1982-08-19 1983-08-18 Un metodo de preparar una forma solida, estable y soluble en agua de 3-desazaguanina Expired ES8502439A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40938982A 1982-08-19 1982-08-19

Publications (2)

Publication Number Publication Date
ES525010A0 ES525010A0 (es) 1985-01-01
ES8502439A1 true ES8502439A1 (es) 1985-01-01

Family

ID=23620279

Family Applications (1)

Application Number Title Priority Date Filing Date
ES525010A Expired ES8502439A1 (es) 1982-08-19 1983-08-18 Un metodo de preparar una forma solida, estable y soluble en agua de 3-desazaguanina

Country Status (10)

Country Link
EP (1) EP0103417B1 (es)
JP (1) JPS5953486A (es)
AT (1) ATE23161T1 (es)
AU (1) AU555803B2 (es)
CA (1) CA1254569A (es)
DE (1) DE3367216D1 (es)
DK (1) DK361083D0 (es)
ES (1) ES8502439A1 (es)
GR (1) GR78670B (es)
IE (1) IE55646B1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043880A1 (es) * 2003-04-22 2005-08-17 Solvay Pharm Gmbh Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896135A (en) * 1973-07-06 1975-07-22 Icn Pharmaceuticals 3-deazaguanine
DD124251A5 (es) * 1975-11-10 1977-02-09
US4322411A (en) * 1980-04-25 1982-03-30 Burroughs Wellcome Co. Anti-inflammatory nucleosides
DE3150486A1 (de) * 1981-12-19 1983-08-25 Merck Patent Gmbh, 6100 Darmstadt Imidazo(4,5-c)pyridine, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IE831779L (en) 1984-02-19
EP0103417A1 (en) 1984-03-21
JPS5953486A (ja) 1984-03-28
GR78670B (es) 1984-09-27
CA1254569A (en) 1989-05-23
ES525010A0 (es) 1985-01-01
AU1741983A (en) 1984-02-23
DK361083D0 (da) 1983-08-08
DE3367216D1 (de) 1986-12-04
EP0103417B1 (en) 1986-10-29
IE55646B1 (en) 1990-12-05
JPH0556351B2 (es) 1993-08-19
AU555803B2 (en) 1986-10-09
ATE23161T1 (de) 1986-11-15

Similar Documents

Publication Publication Date Title
ES541521A0 (es) Un procedimiento para la preparacion de piridazinaminas.
HUT67398A (en) 1h-imidazo(4,5-c)quinolin-4-amin derivatives, pharmaceutical compositions containing them
ATE192153T1 (de) Amino-imidazo (4,5-c) chinoline
EP0221041A3 (en) Benzimidazole derivatives, process for their preparation and their pharmaceutical use
JO1552B1 (en) New pyridizinamine derivatives
NO863061D0 (no) Fremgangsmaate for fremstilling av fysiologisk aktive fenoksyeddiksyrederivater.
IT1213379B (it) Tiazolo [4,5-c]chinoline, procedimento per la loro preparazione e composizioni farmaceutiche che le contengono.
NO860332L (no) Fremgangsmaate for fremstilling av terapeutisk aktive alfa-(2-okso-2,4,5,6,7,7a-heksahydro-tieno(3,2-c)-5-pyridyl)-fenyl-eddiksyre-derivater.
PT86186A (en) Process for the preparation of benzimidazol derivatives and of pharmaceutical compositions containing the same
NO871295D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO870049D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
ES8502439A1 (es) Un metodo de preparar una forma solida, estable y soluble en agua de 3-desazaguanina
NO860091L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 12-amino-pyridazino(4[,5[:3,4)pyrrolo(2,1-a)isokinolin-derivater.
IE813100L (en) Naphthyridine derivatives
EP0204254A3 (en) Substituted hexahydro arylquinolizines, processes for their preparation and pharmaceutical compositions containing them
ES8407478A1 (es) Un procedimiento para la preparacion de nuevos derivados de tetrahidroquinolina.
GB1246727A (en) Therapeutic hypotensive compositions comprising 5-alkylpicolinic acids
ES8304924A1 (es) Un procedimiento para la preparacion de nuevos derivados del acido glutamil-diaminopimelico que contiene una b-lactama.
IL75166A (en) 2-substituted spiro(1,3-oxathiolane-5,3-quinuclidine)derivatives,their preparation and pharmaceutical compositions containing them and 3-hydroxy-3-mercaptomethylquinuclidine as intermidiate therefor
PT82808A (en) Process for the preparation of 1,6-dimethyl-2-halogen-10-alpha-metoxy-ergoline-8beta-methanol 5-bromonicotinate (2-halonicergoline) derivatives and their acid addition salts
IT8522275A0 (it) Uso farmaceutico dellhacido (1-fenilmetil-5-idrossi-1h-indazol3-il)-ossiacetico e dei suoi sali di addizione basica farmaceuticamente accettabili, composizioni farmaceutiche che licontengono.
ES8304925A1 (es) Un procedimiento para la preparacion de nuevos derivados del acido &-glutamil-diaminopimelilo.
CS330884A2 (en) Zpusob vyroby 2-alkythio-1-aminoalkyl-5-oxo-2-pyrrolin-3-karbonitrilu