ES8405776A1 - Procedimiento de preparacion de las polimetileno diaminas n,n'-sustituidas. - Google Patents

Procedimiento de preparacion de las polimetileno diaminas n,n'-sustituidas.

Info

Publication number
ES8405776A1
ES8405776A1 ES521721A ES521721A ES8405776A1 ES 8405776 A1 ES8405776 A1 ES 8405776A1 ES 521721 A ES521721 A ES 521721A ES 521721 A ES521721 A ES 521721A ES 8405776 A1 ES8405776 A1 ES 8405776A1
Authority
ES
Spain
Prior art keywords
chlorine
fluorine
alkyl
substituted
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521721A
Other languages
English (en)
Other versions
ES521721A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of ES8405776A1 publication Critical patent/ES8405776A1/es
Publication of ES521721A0 publication Critical patent/ES521721A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Lubricants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Detergent Compositions (AREA)
  • Furan Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE POLIMETILENO DIAMINAS, N,N-SUSTITUIDAS, DE FORMULA GENERAL (I), EN LA QUE A REPRESENTA UN RADICAL HIDROCARBONADO, QUE TIENE DE TRES A CINTO ATOMOS DE CARBONO EN CADENA RECTA O RAMIFICADA; X REPRESENTA EL GRUPO -CH- O UN ATOMO DE NITROGENO; N REPRESENTA UN NUMERO ENTERO DE 2 A 6; R1 REPRESENTA UN ATOMO DE HIDROGENO O UN RADICAL ALCOHILO CON 1 A 5 ATOMOS DE CARBONO; R2 REPRESENTA UN ATOMO DE HIDROGENO O UN RADICAL ALCOHILO CON 1 A 5 ATOMOS DE CARBONO; Y B REPRESENTA UN RADICAL FENILO, NAFTILO O BENZOFURANILO,Y SUS SALES DE ADICION CON ACIDOS APROPIADOS.CONSISTE EN CONDENSAR UNA DIAMINA DE FORMULA GENERAL (II), EN LA QUE A, X, N Y R1 TIENEN LOS SIGNIFICADOS YA INDICADOS, CON UN DERIVADO HALOGENADO DE FORMULA GENERAL (III), EN LA QUE R2 Y B TIENEN LOS SIGNIFICADOS YA INDICADOS; Y HAL REPRESENTA UN ATOMO DE HALOGENO TAL COMO CLORO O BROMO.DE APLICACION EN EL TRATAMIENTO DE CUALQUIER TIPO DE HIPOXIA TISULAR.
ES521721A 1982-04-21 1983-04-21 Procedimiento de preparacion de las polimetileno diaminas n,n'-sustituidas. Granted ES521721A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8206813A FR2525597B1 (fr) 1982-04-21 1982-04-21 Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
ES8405776A1 true ES8405776A1 (es) 1984-06-16
ES521721A0 ES521721A0 (es) 1984-06-16

Family

ID=9273200

Family Applications (1)

Application Number Title Priority Date Filing Date
ES521721A Granted ES521721A0 (es) 1982-04-21 1983-04-21 Procedimiento de preparacion de las polimetileno diaminas n,n'-sustituidas.

Country Status (13)

Country Link
US (1) US4514399A (es)
EP (1) EP0092479B1 (es)
JP (1) JPS58189168A (es)
AT (1) ATE17724T1 (es)
AU (1) AU555980B2 (es)
CA (1) CA1203803A (es)
DE (1) DE3361972D1 (es)
ES (1) ES521721A0 (es)
FR (1) FR2525597B1 (es)
NZ (1) NZ203954A (es)
OA (1) OA07400A (es)
PT (1) PT76575B (es)
ZA (1) ZA832778B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0145660B1 (de) * 1983-12-02 1990-04-18 Ciba-Geigy Ag Schädlingsbekämpfungsmittel
DE3401675A1 (de) * 1984-01-19 1985-07-25 Bayer Ag, 5090 Leverkusen Neue polyamine und ein verfahren zu ihrer herstellung
GB8421555D0 (en) * 1984-08-24 1984-09-26 Ici Plc Water-soluble dye
DE3438694A1 (de) * 1984-10-23 1986-04-24 Basf Ag, 6700 Ludwigshafen Neue amidoalkylmelamine und aminoalkylmelamine und verfahren zu ihrer herstellung
JPH01121755U (es) * 1988-02-15 1989-08-17
FR2667243B1 (fr) * 1990-09-27 1994-11-04 Adir Utilisation de s derives de la triazine et de la pyrimidine pour l'obtention de medicaments reversant la resistance aux agents anticancereux et antimalariques.
FR2673627B1 (fr) * 1991-03-07 1993-05-07 Adir Triazines et pyrimidines trisubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
EP1053230A1 (en) * 1998-01-13 2000-11-22 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US6225378B1 (en) * 1999-07-01 2001-05-01 Industrial Technology Research Institute Triazine hardener and epoxy composition containing the same
US6943161B2 (en) * 1999-12-28 2005-09-13 Pharmacopela Drug Discovery, Inc. Pyrimidine and triazine kinase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE651967A (es) * 1963-01-11
FR1451232A (fr) * 1963-11-19 1966-01-07 Science Union Et Compagnie Nouveaux dérivés de la pyrimidine et leur procédé de préparation
CH441351A (de) * 1964-06-02 1967-08-15 Geigy Ag J R Verfahren zur Herstellung N2-substituierter 2,4,6-Triamino-1,3,5-triazine
DE1620528A1 (de) * 1965-12-31 1970-06-11 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen basisch substituierten s-Triazinen
GB1256513A (es) * 1968-10-02 1971-12-08
NL7103449A (es) * 1971-03-15 1972-09-19
US4261892A (en) * 1978-04-12 1981-04-14 American Cyanamid Company 2,4,6-Tris-(substituted-amino)-s-triazines

Also Published As

Publication number Publication date
AU1381483A (en) 1983-10-27
PT76575A (fr) 1983-05-01
ATE17724T1 (de) 1986-02-15
EP0092479A1 (fr) 1983-10-26
AU555980B2 (en) 1986-10-16
NZ203954A (en) 1986-01-24
FR2525597B1 (fr) 1985-06-07
FR2525597A1 (fr) 1983-10-28
OA07400A (fr) 1984-11-30
PT76575B (fr) 1985-12-10
EP0092479B1 (fr) 1986-01-29
JPS6240357B2 (es) 1987-08-27
DE3361972D1 (en) 1986-03-13
CA1203803A (fr) 1986-04-29
ZA832778B (en) 1983-12-28
ES521721A0 (es) 1984-06-16
US4514399A (en) 1985-04-30
JPS58189168A (ja) 1983-11-04

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