ES8404325A1 - "procedimiento de obtencion de acidos alfa-n-pirrolil-derivados". - Google Patents
"procedimiento de obtencion de acidos alfa-n-pirrolil-derivados".Info
- Publication number
- ES8404325A1 ES8404325A1 ES512268A ES512268A ES8404325A1 ES 8404325 A1 ES8404325 A1 ES 8404325A1 ES 512268 A ES512268 A ES 512268A ES 512268 A ES512268 A ES 512268A ES 8404325 A1 ES8404325 A1 ES 8404325A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrrolyl
- alpha
- esters
- compositions containing
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ACIDOS DE A -N-PIRROLIL-DERIVADOS, DE FORMULA (I), EN LA QUE X, R, R1, R2, R3 Y R4 PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE UN AMINOESTER DE FORMULA RCHNH2COOR, EN LA QUE R ES UN RADICAL ORGANICO Y R TIENE EL MISMO RIGNIFICADO QUE EN LA FORMULA (I), CON UN DIALCOXITETRAHIDROFURANO O UNO DE SUS DERIVADOS. LA REACCION SE LLEVA A CABO EN MEDIO ACIDO ACETICO, EN PRESENCIA DE EXCESO DE ACETATO SODICO A LA TEMPERATURA DE EBULLICION DE LA MEZCLA DE REACCION.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES512268A ES512268A0 (es) | 1982-05-17 | 1982-05-17 | "procedimiento de obtencion de acidos alfa-n-pirrolil-derivados". |
GB08312804A GB2122189B (en) | 1982-05-17 | 1983-05-10 | Alpha-(n-pyrrolyl)-phenylacetic acids esters thereof their preparation pharmaceutical compositions containing them and therapeutical applications thereof |
US06/494,382 US4563477A (en) | 1982-05-17 | 1983-05-13 | Process for the preparation of alpha-(N-pyrrolyl)-derivative acids, the salts and esters thereof; alpha-(N-pyrrolyl)-phenylacetic acids, the esters thereof, pharmaceutical compositions containing them and therapeutical applications thereof |
FR8307986A FR2526793B1 (fr) | 1982-05-17 | 1983-05-13 | Nouveaux a-(n-pyrrolyl)-acides et leurs sels et esters, utiles comme medicaments et procede de la preparation de tels composes |
DE3317666A DE3317666A1 (de) | 1982-05-17 | 1983-05-14 | Verfahren zur herstellung von (alpha)-(n-pyrrolyl)-substituierten saeuren, deren salzen und estern, sowie dieselben enthaltende pharmazeutische zusammensetzungen |
BE0/210793A BE896769A (fr) | 1982-05-17 | 1983-05-17 | Nouveaux & (n pyrrolyl)-acides et leurs sels et esters, utiles comme medicaments et procede pour la preparation de tels composes. |
JP58085166A JPS5910563A (ja) | 1982-05-17 | 1983-05-17 | α−(N−ピロリル)−フエニル酢酸誘導体およびその製造方法 |
CH2667/83A CH658786A5 (fr) | 1982-05-17 | 1983-05-17 | Medicaments qui contiennent d'alpha-(n-pyrrolyl)-acides ou de leurs sels ou esters. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES512268A ES512268A0 (es) | 1982-05-17 | 1982-05-17 | "procedimiento de obtencion de acidos alfa-n-pirrolil-derivados". |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8404325A1 true ES8404325A1 (es) | 1984-05-16 |
ES512268A0 ES512268A0 (es) | 1984-05-16 |
Family
ID=8484145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES512268A Granted ES512268A0 (es) | 1982-05-17 | 1982-05-17 | "procedimiento de obtencion de acidos alfa-n-pirrolil-derivados". |
Country Status (8)
Country | Link |
---|---|
US (1) | US4563477A (es) |
JP (1) | JPS5910563A (es) |
BE (1) | BE896769A (es) |
CH (1) | CH658786A5 (es) |
DE (1) | DE3317666A1 (es) |
ES (1) | ES512268A0 (es) |
FR (1) | FR2526793B1 (es) |
GB (1) | GB2122189B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3727114A1 (de) * | 1987-08-14 | 1989-02-23 | Basf Ag | Verfahren zur herstellung von pyrrolen |
FR2647674B1 (fr) * | 1989-06-06 | 1994-06-03 | Centre Nat Rech Scient | Derives de pyrrole utilisables notamment comme intercepteurs d'especes activees du dioxygene - leur procede de preparation - compositions les contenant |
EP0442448A3 (en) | 1990-02-13 | 1992-08-12 | Bristol-Myers Squibb Company | Heterocyclic carboxylic acids and esters |
US5034409A (en) * | 1990-02-13 | 1991-07-23 | Bristol-Myers Squibb Company | Pyrrole carboxylic acids and esters for blood platelet aggregation inhibition |
KR101044880B1 (ko) * | 2008-06-12 | 2011-06-28 | 일양약품주식회사 | 항궤양제 화합물의 합성에 유용한 중간체의 제조방법 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50130756A (es) * | 1974-03-30 | 1975-10-16 | ||
DE2647368A1 (de) * | 1975-10-23 | 1977-05-05 | Ciba Geigy Ag | Alpha-(1-pyrrolyl)-carbonsaeure-3- phenoxy-benzylester, verfahren zu ihrer herstellung und ihre verwendung |
JPS52128369A (en) * | 1976-04-17 | 1977-10-27 | Nissan Chem Ind Ltd | Alpha-isopropyl-substituted pyrrole-1-acetic acid ester |
JPS5326322A (en) * | 1976-08-20 | 1978-03-11 | Nissan Chem Ind Ltd | Insecticidal composition |
-
1982
- 1982-05-17 ES ES512268A patent/ES512268A0/es active Granted
-
1983
- 1983-05-10 GB GB08312804A patent/GB2122189B/en not_active Expired
- 1983-05-13 US US06/494,382 patent/US4563477A/en not_active Expired - Fee Related
- 1983-05-13 FR FR8307986A patent/FR2526793B1/fr not_active Expired
- 1983-05-14 DE DE3317666A patent/DE3317666A1/de active Granted
- 1983-05-17 BE BE0/210793A patent/BE896769A/fr not_active IP Right Cessation
- 1983-05-17 JP JP58085166A patent/JPS5910563A/ja active Pending
- 1983-05-17 CH CH2667/83A patent/CH658786A5/fr not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB2122189A (en) | 1984-01-11 |
JPS5910563A (ja) | 1984-01-20 |
FR2526793B1 (fr) | 1985-09-06 |
GB8312804D0 (en) | 1983-06-15 |
DE3317666C2 (es) | 1990-10-25 |
GB2122189B (en) | 1986-04-16 |
US4563477A (en) | 1986-01-07 |
BE896769A (fr) | 1983-09-16 |
DE3317666A1 (de) | 1983-11-17 |
CH658786A5 (fr) | 1986-12-15 |
FR2526793A1 (fr) | 1983-11-18 |
ES512268A0 (es) | 1984-05-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT76316B (en) | Process for the preparation of esters of substituted pyridino- 3,5-dicarboxylic and/or of pyrano-3,5-dicarboxylic acids having an hypotensive effect and application thereof for the preparation of pharmaceutical compositions having an hypotensive effect | |
SG15689G (en) | Substituted acyl derivatives of 1,2,3,4-tetrahydroiso-quinoline-3-carboxylic acids,salts thereof,pharmaceutical compositions containing the derivatives or salts,and the production of the same | |
IL110216A0 (en) | Valproic acid amide and 2-valproenoic acid amide derivatives, their preparation and pharmaceutical compositions containing them | |
HUT50841A (en) | Process for producing (cycloalkylamino)-methylene-bis(phosphoric acid) derivatives and pharmaceutical compositions comprising such compounds as active ingredient | |
DE3070912D1 (en) | Pharmaceutical heterocyclic compounds, processes for their preparation and compositions containing them | |
PH23607A (en) | Amide derivatives and pharmaceutical composition containing said compounds | |
FI892497A0 (fi) | Menetelmä terapeuttisesti aktiivisten bentsamidijohdannaisten valmistamiseksi | |
ES8301927A1 (es) | Procedimiento de preparacion de acidos azabiciclohexano car-boxilicos y de sus sales | |
ES8702343A1 (es) | Un procedimiento para la produccion de un derivado de diami-das de n-acilaminoacidos | |
ES8507090A1 (es) | Procedimiento para la obtencion de nuevas 1, 5-benzotiacepinas | |
PT87277A (pt) | Process for the preparation of new bicyclic compounds and pharmaceutical compositions comprising same | |
ES8504682A1 (es) | Un procedimiento para la preparacion de compuestos nitro alifaticos | |
ES8404325A1 (es) | "procedimiento de obtencion de acidos alfa-n-pirrolil-derivados". | |
PT91607A (pt) | Process for the preparation of substituted beta-diketones and of pharmaceutical compositions containing them | |
ES8701143A1 (es) | Un procedimiento para la preparacion de nuevos aminas terciarias. | |
HUT60498A (en) | Process for producing 2-(substituted pyrrolidinylthio)-carbapenem derivatives and pharmaceutical compositions comprising such compounds | |
ES8100249A1 (es) | Un metodo para la preparacion de un compuesto de acido hi- droxamico | |
ATE123487T1 (de) | Derivate der kaffeinsäure und sie enthaltende pharmazeutische zusammensetzungen. | |
DE3362846D1 (en) | Derivatives of benzo-1,2-thiazine-1,1-dioxide, a process for their preparation and pharmaceutical compositions containing the same | |
ES8606320A1 (es) | Procedimiento de obtencion de esteres del acido ascorbico | |
ES2006361A6 (es) | Un procedimiento para preparar derivados de insoindolinilo opticamente activos. | |
DE3665593D1 (en) | Peptide immunostimulants | |
DE3462400D1 (en) | Carboxylic acid derivatives, processes for their production and pharmaceutical preparations containing them | |
DE2964141D1 (en) | Alpha-ethinyl-alpha-aminoacids and their esters, and pharmaceutical compositions containing them | |
HUT45016A (en) | Herbicides containing as active substance derivatives of piridil-phenil-ether and process for production of these derivatives |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970612 |